Search results for "PTH"
showing 10 items of 458 documents
Chemical, biochemical and microbial diversity through a Pachic Humudept profile in a temperate upland grassland
2013
There is great interest in understanding the factors that drive soil microbial activity and community composition in upland grassland ecosystems. We investigated the role of vertical gradients of chemical properties and various soluble C and N pools on soil microbial community structure by using a combination of chemical and biochemical methods coupled with PCR-denaturing gradient gel electrophoresis (DGGE) community fingerprinting and phospholipid fatty acid (PLFA) profiling. Soil samples were collected at increasing depth from a temperate upland grassland. Soil organic matter-related pools (total organic C and total Kjeldahl N) and functionally related active pools (microbial biomass C an…
Phytoplankton assemblages in twenty-one Sicilian reservoirs: relationships between species composition and environmental factors
2000
Data collected in a limnological survey, carried out between 1987 and 1988 on 21 Sicilian reservoirs of varying trophic state, were ordinated using CANOCO 3.1 to generalise the way in which the structure of phytoplankton assemblage is conditioned by both physical and chemical variables. The results showed that in these man-made lakes, characterised by conspicuouswater-level fluctuations, the annual and interannual variability in the abundance and composition of phytoplankton may be strongly influenced by their peculiar hydraulic regimes rather than by nutrient availability. In particular, it was highlighted that, from the early summer, water abstraction often leads to increased circulation …
Expression levels of PTHrP splicing variants and PTHrP promoter methylation states in differentiating mesenchymal stem cells
2012
PTHrP [38-94]-amide is a DNA-binding factor: cytogenetic and molecular evidence and biological effect on normal and neoplastic human breast cells
2004
Il PTHrP [38-94]-amide è un fattore “DNA-binding”: dati citogenetica e molecolari ed effetto biologico su cellule epiteliali mammarie immortalizzate …
2004
Metilazione del DNA in artrite reumatoide
2005
Lo stato di metilazione del DNA genomico e del gene PTHrP è stato valutato con tecniche molecolari e citogenetiche in artrite reumatoide (AR), patologia autoimmune caratterizzata anche da alta incidenza di linfomi e da ipercalcemia per overespressione del gene PTHrP. La metilazione del DNA, infatti, ha un ruolo critico nello sviluppo delle malattie neoplastiche; il gene PTHrP avendo tre promotori uno dei quali contiene un’isola CpG è un buon candidato per la deregolazione da alterato pattern di metilazione locale. Le indagini sulla metilazione genomica, condotte su DNA estratto da sangue periferico di pazienti e di donatori e amplificato in reazioni di Methylation-Sensitive Arbitrarily Prim…
Monitoring tropical forests under a functional perspective with satellite-based vegetation optical depth.
2020
Monitoring ecosystem functions in forests is a priority in a climate change scenario, as climate-induced events may initially alter the functions more than slow-changing attributes, such as biomass. The ecosystem functional properties (EFPs) are quantities that characterize key ecosystem processes. They can be derived by point observations of gas and energy exchanges between the ecosystems and the atmosphere that are collected globally at FLUXNET flux tower sites and upscaled at ecosystem level. The properties here considered describe the ability of ecosystems to optimize the use of resources for carbon uptake. They represent functional forest information, are dependent on environmental dri…
Continuous hand openness detection using a Kinect-like device
2014
This paper presents a novel method to reproduce in real time the opening and closing gestures of a human hand, animating a three-dimensional model of it. In other works, this result can be achieved by mapping a set of significant points of a real hand on the corresponding points of the model to animate. We propose an alternative way to produce the same effect without mapping points, but using a level-based estimation of the degree of opening of the hand. The experiments have been executed using Microsoft KinectTM, but the method would work on any other Kinect-like devices (as defined herein). The results obtained are particularly encouraging and demonstrate real-time performance of the syst…
Treatment adherence and QoL with intermittent PTH therapy: Results from a multicentre Italian study after 6 months
2011
This ongoing multicentre study was carried out to investigate the adherence to intermittent parathyroid hormone treatment and the effect on QoL in a typical Italian population eligible for drug reimbursement (i.e. a new vertebral or hip fracture following at least one year of anti-resorptive therapy or three severe vertebral fractures or two severe and one femur fracture). 204 female patients (mean age: 72.6±8.3) were enrolled between March 2008 and April 2009. These patients were treated with PTH (PTH 1–34 or PTH 1–84) according to Italian legislation. Here, we report the results obtained at month 6.
Severe senile osteoporosis: synergism of action between PTH 1-34 and rehabilitation
2012
An analysis of the data shows that the PTH 1-34 in association with specific rehabilitation treatment is effective in reducing early pain borne by the dorsal-lumbar spine, to avoid the risk of new fractures, improve balance and gait to correct a good quality of life. Even taking into account the small number of patients, we emphasize the absence of new osteoporotic fractures in women who have also physical therapy and therapeutic exercise.