Search results for "PTO"

showing 10 items of 28599 documents

From Country Girl in Southern Finland to Longitudinal Research into Alternatives to Aggression and Violence

2021

Lea Pulkkinen, born in Finland in 1939, is Emerita Professor of Psychology at the University of Jyväskylä (Finland). She is best known for creating the ongoing Jyväskylä Longitudinal Study of Personality and Social Development (JLSPSD). The study was specifically intended to test the hypothesis that the human brain allows for more variation in behavior than the simple ‘fight or flight’ response observed in animal studies of aggression. She further hypothesized that humans’ capacity for cognitive control over emotional behavior was the key factor involved in controlling aggressive behavior. These hypotheses led her to devise an impulse control model to depict behavioral alternatives, which s…

self-regulationLongitudinal studyaggressiivisuusomaelämäkerrallisuushenkilöhistoriamedia_common.quotation_subjectitsesääntelypitkittäistutkimusDevelopmental psychologyFight-or-flight responseemotional behaviormielenterveystunteetmedicinePersonalitycognitive controlsosiaalinen kehitysGirlwork forceelämänhistoriamedia_commonsocial developmenttutkimushistoriaAggressionfight or flightSocial changelongitudinal studytutkijatpersoonallisuusMental healthtyöhönsijoittuminenImpulse controlpersonalitypersoonallisuuden psykologiatyövoimamedicine.symptomPsychologyimpulse controlmental health
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Dynamic interplay of depression, perfectionism and self-regulation on procrastination

2014

WOS: 000335211600007

self-regulationmedia_common.quotation_subjectProcrastinationMetacognitioncognitive and behavioural componentsCognitionAcademic achievementAffect (psychology)affectiveprocrastinationdepressionmedicineAnxietyperfectionismmedicine.symptomBig Five personality traitsPsychologyPath analysis (statistics)Applied PsychologyClinical psychologymedia_commonBritish Journal of Guidance & Counselling
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Low toxicity metal halide semiconductors for optoelectronics and thermoelectrics

2023

Amb la finalitat de lluitar contra el canvi climàtic i donar suport a les energies renovables i no contaminants, l'objectiu principal d'aquesta tesi és la cerca i l'estudi de nous materials amb potencial aplicació en tres grans àrees d'investigació: la fotovoltaica, la termoelèctrica i els díodes emissors de llum (LED). Atés que molts dels materials emprats en aquestes àrees contenen components tòxics i nocius per al medi ambient, els materials desenvolupats en aquesta tesi a més presenten una baixa toxicitat i es poden preparar mitjançant mètodes de síntesis i deposició més sostenibles i ecològics. Concretament, es van utilitzar dos mètodes de síntesis: la mecanosíntesi en sec per molta de…

semiconductoresmaterialesLEDsfotovoltaicaUNESCO::QUÍMICAtermoeléctricaoptoelectrónica
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Cross section for bb¯ production via dielectrons in d + Au collisions at √sNN = 200 GeV

2015

We report a measurement of e+e− pairs from semileptonic heavy-flavor decays in d + Au collisions at √sNN = 200 GeV. By exploring the mass and transverse-momentum dependence of the yield, the bottom decay contribution can be isolated from charm, and quantified by comparison to PYTHIA and MC@NLO simulations. The resulting bb¯-production cross section is σdAu bb¯ = 1.37 ± 0.28 (stat) ± 0.46 (syst) mb, which is equivalent to a nucleon-nucleon cross section of σ NN bb = 3.4 ± 0.8 (stat) ± 1.1 (syst) μb. peerReviewed

semileptonic heavy-flavor decaysHigh Energy Physics::Phenomenologyd+Au collisions at sNN=200 GeVHigh Energy Physics::ExperimentNuclear Experimentmeasurement of e+e- pairs
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"Table 7" of "Cross section for $b\bar{b}$ production via dielectrons in d$+$Au collisions at $\sqrt{s_{_{NN}}}=200$ GeV"

2023

$b\bar{b}$ cross section

semileptonic heavy-flavor decaysb ̄b-production cross sectionmc@nloppg156pythia$d$ + Au200.0
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Bcl-xL as a Modulator of Senescence and Aging

2021

Many features of aging result from the incapacity of cells to adapt to stress conditions. When cells are overwhelmed by stress, they can undergo senescence to avoid unrestricted growth of damaged cells. Recent findings have proven that cellular senescence is more than that. A specific grade of senescence promotes embryo development, tissue remodeling and wound healing. However, constant stresses and a weakening immune system can lead to senescence chronicity with aging. The accumulation of senescent cells is directly related to tissue dysfunction and age-related pathologies. Centenarians, the most aged individuals, should accumulate senescent cells and suffer from their deleterious effects,…

senescenceReviewmedicine.disease_causelcsh:Chemistry0302 clinical medicineImmunologic Surveillancelcsh:QH301-705.5SpectroscopyCellular Senescenceimmunosenescence0303 health sciencesapoptosisGeneral MedicineImmunosenescenceComputer Science ApplicationsCell biologyOrgan Specificity030220 oncology & carcinogenesisDisease SusceptibilitycentenariansProtein BindingSignal TransductionSenescencebcl-X ProteinBcl-xLBiologyCatalysisInorganic Chemistry03 medical and health sciencesImmune systemStress PhysiologicalmedicineAnimalsHumansPhysical and Theoretical ChemistrySenolyticMolecular Biology030304 developmental biologyBcl-xLOrganic ChemistryIntrinsic apoptosisagingGene Expression Regulationlcsh:Biology (General)lcsh:QD1-999senolyticsbiology.proteinWound healingOxidative stressBiomarkersDNA DamageInternational Journal of Molecular Sciences
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Serenoa repens, lycopene and selenium versus tamsulosin for the treatment of LUTS/BPH. An Italian multicenter double-blinded randomized study between…

2014

serenoa repensMaleProstatic HyperplasiaAntioxidantsSettore MED/24 - UrologiaSeleniumDouble-Blind MethodDrug TherapyLower Urinary Tract SymptomsSerenoa80 and overHumansBPH; LUTS; lycopene; phytotherapy; selenium; serenoa repens; tamsulosin; Aged; Aged 80 and over; Antioxidants; Carotenoids; Double-Blind Method; Drug Therapy Combination; Humans; Italy; Lower Urinary Tract Symptoms; Male; Middle Aged; Phytotherapy; Prostatic Hyperplasia; Quality of Life; Selenium; Serenoa; Sulfonamides; Treatment Outcome; Urodynamics; Urological AgentsAgedSulfonamidesLUTSphytotherapyMiddle AgedlycopeneCarotenoidsBPH LUTS lycopene phytotherapy selenium serenoa repens tamsulosinUrodynamicsTreatment OutcomeItalyBPHtamsulosinCombinationQuality of LifeUrological Agentsserenoa repens; lycopene; selenium; tamsulosin; LUTS; BPH; phytotherapy
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Comparison of essential oil components and in vitro anticancer activity in wild and cultivated Salvia verbenaca.

2015

The objectives of our research were to study the chemical composition and the in vitro anticancer effect of the essential oil of Salvia verbenaca growing in natural sites in comparison with those of cultivated (Sc) plants. The oil from wild (Sw) S. verbenaca presented hexadecanoic acid (23.1%) as the main constituent, while the oil from Sc plants contained high quantities of hexahydrofarnesyl acetone (9.7%), scarce in the natural oil (0.7%). The growth-inhibitory and proapoptotic effects of the essential oils from Sw and Sc S. verbenaca were evaluated in the human melanoma cell line M14, testing cell vitality, cell membrane integrity, genomic DNA fragmentation and caspase-3 activity. Both t…

sesquiterpenePalmitic AcidApoptosisDNA FragmentationPlant ScienceSalviaPlant OilBiochemistryessential oillaw.inventionAnalytical ChemistryTerpenePalmitic acidchemistry.chemical_compoundfoodlawCell Line TumorBotanymelanomaOils VolatileHumansPlant OilsSalviaFragmentation (cell biology)Essential oilLamiaceaebiologyTraditional medicineSalvia verbenacaTerpenesCaspase 3Medicine (all)Organic ChemistryApoptosibiology.organism_classificationAntineoplastic Agents Phytogenicfood.foodchemistryTerpeneDNA fragmentationSalvia verbenacaLamiaceaeHuman
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Mucin 1 deficiency mediates corticosteroid insensitivity in asthma

2019

BACKGROUND: The loss of corticosteroid efficacy is an important issue in severe asthma management and may lead to poor asthma control and deterioration of airflow. Recent data indicate that Mucin 1 (MUC1) membrane mucin can mediate corticosteroid efficacy in chronic rhinosinusitis, but the role of MUC1 in uncontrolled severe asthma is unknown. The objective was to analyze the previously unexplored role of MUC1 on corticosteroid efficacy in asthma. METHODS: Mucin 1 expression was evaluated by real-time PCR in human bronchial epithelial cells (HBEC) and blood neutrophils from uncontrolled severe asthma (n=27), controlled mild asthma (n=16), and healthy subjects (n=13). IL-8, MMP9, and GM-CSF …

severe asthma0301 basic medicineLipopolysaccharideNeutrophilsmedicine.drug_classcorticosteroid insensitivityImmunologyAnti-Inflammatory AgentsDrug ResistanceMUC1DexamethasoneMice03 medical and health scienceschemistry.chemical_compoundReceptors Glucocorticoid0302 clinical medicineGlucocorticoid receptorAdrenal Cortex Hormonesimmune system diseasesmedicineAnimalsHumansImmunology and AllergyCells CulturedMUC1DexamethasoneAsthmabiologybusiness.industryMucin-1MucinEpithelial Cellsmedicine.diseaseAsthmarespiratory tract diseasesOvalbumin030104 developmental biology030228 respiratory systemchemistryCase-Control StudiesImmunologybiology.proteinCorticosteroidbusinessmedicine.drugAllergy
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Real-world experience with dupilumab in severe asthma: One-year data from an italian named patient program

2021

Raffaele Campisi,1 Claudia Crimi,1 Santi Nolasco,2 Bianca Beghè,3 Leonardo Antonicelli,4 Gabriella Guarnieri,5 Nicola Scichilone,6 Morena Porto,2 Luigi Macchia,7 Giulia Scioscia,8 Maria Pia Foschino Barbaro,8 Alberto Papi,9 Nunzio Crimi1,2 1Respiratory Medicine Unit, A.O.U. Policlinico “G. Rodolico -San Marco”, Catania, Italy; 2Department of Clinical and Experimental Medicine, Section of Respiratory Diseases, University of Catania, Catania, Italy; 3Respiratory Medicine Unit, Department of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 4Allergy Unit, Department of Internal Medicine, Ancona University Hospital, Ancona, Italy; 5Department of Car…

severe asthmaPulmonary and Respiratory MedicineSevere asthmareal-worldmedicine.medical_specialtyTreatment responseSevere asthmaSocio-culturaleDupilumab Named Patient Program Oral corticosteroids Real-world Severe asthmaHypereosinophiliaDupilumaboral corticosteroidsSettore MED/10 - Malattie Dell'Apparato Respiratoriolaw.inventionNamed Patient Program dupilumab oral corticosteroids real-world severe asthma03 medical and health sciences0302 clinical medicineRandomized controlled triallawdupilumabInternal medicineOral corticosteroidsJournal of Asthma and AllergymedicineImmunology and Allergy0601 history and archaeologyOriginal Research060102 archaeologybusiness.industryRetrospective cohort study06 humanities and the artsRC581-607Named Patient ProgramEosinophilDupilumabmedicine.anatomical_structureReal-world030228 respiratory systemCohortImmunologic diseases. Allergymedicine.symptombusinessDupilumab; Named Patient Program; Oral corticosteroids; Real-world; Severe asthma
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