Search results for "PULMONARY-FUNCTION"

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High volume and low concentration of anaesthetic solution in the perivascular interscalene sheath determines quality of block and incidence of compli…

2006

Background and objective: In the perivascular sheath of the brachial plexus, the volume of anaesthetic solution determines the quality of anaesthetic cover. Fibrous septa may divide the perivascular space into compartments, leading to inadequate diffusion of the anaesthetic solution. The aim of our study was to obtain good anaesthesia and less complications using high volume of low concentration anaesthetic solution, overcoming the obstacle of the septa with a double approach to the scalene sheath. Methods: Sixty patients scheduled for shoulder capsuloplasty received both Winnie interscalene brachial plexus block and Pippa proximal cranial needle approach. The patients were randomly assigne…

AdultMalemedicine.medical_specialtyEpinephrineLidocaineBRACHIAL-PLEXUS BLOCK; BEZOLD-JARISCH REFLEX; SITTING POSITION; HEMIDIAPHRAGMATIC PARESIS; SHOULDER ARTHROSCOPY; FUNCTIONAL-ANATOMY; PULMONARY-FUNCTION; ULTRASONOGRAPHY; MEPIVACAINEFUNCTIONAL-ANATOMYMEPIVACAINEULTRASONOGRAPHYSITTING POSITIONAxillary blockBRACHIAL-PLEXUS BLOCKBradycardiaHumansMedicineBrachial PlexusAnesthetics LocalPerivascular spaceBEZOLD-JARISCH REFLEXVolume concentrationAgedBrachial plexus blockBupivacaineShoulder Jointbusiness.industryLidocainePULMONARY-FUNCTIONNerve BlockMiddle AgedAdrenergic AgonistsBupivacaineSurgeryParesisPhrenic NerveAnesthesiology and Pain Medicinemedicine.anatomical_structureAnesthesiaHEMIDIAPHRAGMATIC PARESISFemaleSHOULDER ARTHROSCOPYHypotensionbusinessBrachial plexusmedicine.drug
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Assessing biomarkers in a real-world severe asthma study (ARIETTA)

2016

AbstractThe prognostic value of asthma biomarkers in routine clinical practice is not fully understood. ARIETTA (NCT02537691) is an ongoing, prospective, longitudinal, international, multicentre real-world study designed to assess the relationship between asthma biomarkers and disease-related health outcomes. The trial aims to enrol and follow for 52 weeks approximately 1200 severe asthma patients from approximately 160 sites in more than 20 countries. Severe asthmatics, treated with daily inhaled corticosteroid (≥500 μg of fluticasone propionate or equivalent) and at least 1 second controller medication are to be included. In this real-world study, patients will be treated according to the…

MaleSevere asthmaCardiac & Cardiovascular SystemsExacerbationAIRWAY INFLAMMATIONRespiratory SystemEosinophilSeverity of Illness Indexlaw.inventionDOUBLE-BLIND0302 clinical medicineQuality of lifeRandomized controlled trialAdrenal Cortex HormoneslawForced Expiratory VolumeProspective Studies030212 general & internal medicineProspective cohort studyFluticasoneEPITHELIAL-CELLSExacerbationRANDOMIZED CONTROLLED-TRIALPrognosis3. Good healthTO-SEVERE ASTHMAFemaleLife Sciences & Biomedicinemedicine.drugAdultPulmonary and Respiratory Medicinemedicine.medical_specialtyPHENOTYPESNitric Oxide1102 Cardiovascular Medicine And HaematologyFluticasone propionate03 medical and health sciencesPredictive Value of TestsAdministration InhalationSeverity of illnessmedicineHumansNITRIC-OXIDE SYNTHASEIntensive care medicineCOMBINATIONAsthmaScience & Technologybusiness.industryPULMONARY-FUNCTION1103 Clinical SciencesBiomarkerImmunoglobulin Emedicine.diseaseAsthmarespiratory tract diseasesEosinophilsBiomarker; Eosinophil; Exacerbation; Periostin; Severe asthma; Pulmonary and Respiratory MedicinePeriostin030228 respiratory systemQuality of LifeCardiovascular System & CardiologyFluticasonebusinessCell Adhesion MoleculesBiomarkersRespiratory Medicine
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