Search results for "Pain"
showing 10 items of 6371 documents
Investigation of the consequences of the modifiable areal unit problem in macroscopic traffic safety analysis: A case study accounting for scale and …
2019
Abstract Traffic safety analysis at the macroscopic level usually relies on previously defined areal traffic analysis zones (TAZs) that are used as the units of investigation. Hence, statistical inference is made on the basis of such units, implying that the consideration of a certain TAZ configuration may influence the results and conclusions achieved. Regarding this, the modifiable areal unit problem (MAUP) is a well-known issue in the field of spatial statistics, which refers to the effects that arise in statistical properties and estimations when there is a change in areal units of analysis. In this paper, the consequences of MAUP have been investigated through a dataset of traffic cras…
The Catholic Nation under Liberalism. Perspectives on Religious Unity in Liberal Spain, 1808-1868
2015
El artículo estudia los significados históricos que tuvo la afirmación de la unidad religiosa de la nación española en el liberalismo decimonónico. A partir de las premisas historiográficas que han renovado las reflexiones en torno a las relaciones entre religión, política y nación, los autores analizan la herencia plural de los ilustrados del último tercio del siglo XVIII y el sentido de la homogeneidad confesional de la nación soberana, esbozada por la Constitución de 1812. La confesionalidad religiosa no impidió las posibilidades de emancipación individual. Por el contrario, el primer liberalismo tendió a un reforzamiento mutuo de las identidades religiosa y nacional, al tiempo que confi…
Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study
2023
Nicotinamide adenine dinucleotide (NAD + ) precursor nicotinamide riboside (NR) has emerged as a promising compound to improve obesity-associated mitochondrial dysfunction and metabolic syndrome in mice. However, most short-term clinical trials conducted so far have not reported positive outcomes. Therefore, we aimed to determine whether long-term NR supplementation boosts mitochondrial biogenesis and metabolic health in humans. Twenty body mass index (BMI)–discordant monozygotic twin pairs were supplemented with an escalating dose of NR (250 to 1000 mg/day) for 5 months. NR improved systemic NAD + metabolism, muscle mitochondrial number, myoblast differentiation, and gut microbiota compos…
Gli affreschi e le tele
2023
The pictorial decoration of the church of Santa Maria La Porta in Geraci Siculo. Critical historical analysis of the canvases and frescoes. Iconographic readings, stylistic analysis and attributions
Synnytysloma isille? : vanhempainvapaat ja sukupuolten tasa-arvo
2020
2020
Strontium isotopes in biogenic apatite, especially enamel, are widely employed to determine provenance and track migration in palaeontology and archaeology. Body tissues record the 87Sr/86Sr of bioavailable Sr of ingested food and water. To identify non-local individuals, knowledge of the 87Sr/86Sr of a non-migratory population is required. However, varying factors such as tissue turnover rates, feeding selectivity, Sr content, digestibility of food, and the ingestion of mineral dust can influence body tissue 87Sr/86Sr. To evaluate the Sr contribution of diet and water to mammalian hard tissues 87Sr/86Sr, controlled feeding studies are necessary. Here we present 87Sr/86Sr from controlled fe…
COVID-19 Infection Process in Italy and Spain: Are the Data Talking?
2020
Background: COVID-19 has spread successfully worldwide in a matter of weeks. After the example of China, all the affected countries are taking hard-confinement measures to control the infection and to gain some time to diminish the big amount of cases that arrive to hospital. Although the measures in China reduced the percentages of new cases, this is not seen in other countries that have taken similar measures, such as Italy and Spain. Now we are in the middle of a battle trying to prevent the healthcare system from collapsing while it effectively responds to the needs of patients who are infected and require hospitalization. Methods: Using China as a mirror of what could happen in our cou…
The need for an independent evaluation of the COVID-19 response in Spain.
2020
Spain has been hit hard by COVID-19, with more than 300 000 cases, 28 498 confirmed deaths,1 and around 44 000 excess deaths, as of Aug 4, 2020.2 More than 50 000 health workers have been infected, and nearly 20 000 deaths were in nursing homes.3 With a population of 47 million, these data place Spain among the worst affected countries. Spain is also reported to have one of the best performing health systems in the world4 and ranks 15th in the Global Health Security index.5 So how is it possible that Spain now finds itself in this position?