Search results for "Palaeoproteomics"

showing 3 items of 3 documents

'Palaeoshellomics' reveals the use of freshwater mother-of-pearl in prehistory

2019

The extensive use of mollusc shell as a versatile raw material is testament to its importance in prehistoric times. The consistent choice of certain species for different purposes, including the making of ornaments, is a direct representation of how humans viewed and exploited their environment. The necessary taxonomic information, however, is often impossible to obtain from objects that are small, heavily worked or degraded. Here we propose a novel biogeochemical approach to track the biological origin of prehistoric mollusc shell. We conducted an in-depth study of archaeological ornaments using microstructural, geochemical and biomolecular analyses, including ‘palaeoshellomics’, the first…

0301 basic medicine010506 paleontology1300QH301-705.5Science[SDV]Life Sciences [q-bio]Fresh Waterengineering.material01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologypalaeoproteomicsPrehistory03 medical and health sciencesBiochemistry and Chemical BiologyMollusc shelltandem mass spectrometryHumansHuman Activities14. Life underwaterBiology (General)Nacreornaments0105 earth and related environmental sciencesEvolutionary Biology2400General Immunology and MicrobiologyEcologyGeneral NeuroscienceQ2800Rmollusc shellsPaleontologyOrnamentsGeneral MedicinebiomineralizationEurope030104 developmental biologyGeographyengineeringprehistoryMedicineOtherPearlResearch Article
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Middle Pleistocene protein sequences from the rhinoceros genus Stephanorhinus and the phylogeny of extant and extinct Middle/Late Pleistocene Rhinoce…

2017

BackgroundAncient protein sequences are increasingly used to elucidate the phylogenetic relationships between extinct and extant mammalian taxa. Here, we apply these recent developments to Middle Pleistocene bone specimens of the rhinoceros genusStephanorhinus. No biomolecular sequence data is currently available for this genus, leaving phylogenetic hypotheses on its evolutionary relationships to extant and extinct rhinoceroses untested. Furthermore, recent phylogenies based on Rhinocerotidae (partial or complete) mitochondrial DNA sequences differ in the placement of the Sumatran rhinoceros (Dicerorhinus sumatrensis). Therefore, studies utilising ancient protein sequences from Middle Pleis…

0301 basic medicineAncient proteinsBioinformaticsZoologylcsh:MedicineRhinocerosProtein degradationBiologyRhinocerotidaeGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesWoolly rhinocerosbiology.animalMolecular BiologyStephanorhinusStephanorhinusGeneral Neurosciencelcsh:RPaleontologyPalaeoproteomicsGeneral MedicineCoelodontabiology.organism_classificationDicerorhinus sumatrensisEquusEvolutionary StudiesPhylogenetics030104 developmental biologyEvolutionary biologyEquidaeGeneral Agricultural and Biological Sciences
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Shell palaeoproteomics: first application of peptide mass fingerprinting for the rapid identification of mollusc shells in archaeology.

2020

10 pages; International audience; Molluscs were one of the most widely-used natural resources in the past, and their shells are abundant among archaeological findings. However, our knowledge of the variety of shells that were circulating in prehistoric times (and thus their socio-economic and cultural value) is scarce due to the difficulty of achieving taxonomic determination of fragmented and/or worked remains. This study aims to obtain molecular barcodes based on peptide mass fingerprints (PMFs) of intracrystalline proteins, in order to obtain shell identification. Palaeoproteomic applications on shells are challenging, due to low concentration of molluscan proteins and an incomplete unde…

0301 basic medicineFreshwater bivalve[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and PrehistoryBiophysicsShell (structure)BiologyBiochemistryPeptide Mapping03 medical and health sciencesPeptide mass fingerprintingAnimal Shells[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]Mollusc shellMollusc shellAnimalsPeptide mass fingerprintPeptide-mass fingerprintPhylogenyShellomics030102 biochemistry & molecular biologyPhylogenetic treeMALDI-TOF mass spectrometry; Mollusc shell; Palaeoproteomics; Peptide mass fingerprint; ShellomicsMALDI-TOF mass spectrometryPalaeoproteomicsArchaeologyBivalvia030104 developmental biologyTaxonArchaeologyIdentification (biology)Peptides
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