Search results for "Paleogenetics"

showing 10 items of 17 documents

Ancient DNA from European early neolithic farmers reveals their near eastern affinities.

2010

The first farmers from Central Europe reveal a genetic affinity to modern-day populations from the Near East and Anatolia, which suggests a significant demographic input from this area during the early Neolithic.

010506 paleontologyArchaeogeneticsQH301-705.5PopulationPopulation geneticsBiologyDNA Mitochondrial01 natural sciencesGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesDemic diffusionGenetics and Genomics/Population GeneticsHuman population geneticsHumansBiology (General)education030304 developmental biology0105 earth and related environmental sciences2. Zero hungerGeneticsEvolutionary Biology0303 health scienceseducation.field_of_studyGeneral Immunology and MicrobiologyFossilsGeneral NeurosciencePaleogeneticsAgricultureEmigration and ImmigrationEvolutionary Biology/Human EvolutionEuropeAncient DNAEvolutionary biologySynopsisGeneral Agricultural and Biological SciencesResearch ArticleHuman mitochondrial DNA haplogroupPLoS Biology
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Spatio-temporal dynamics of genetic variation in the Iberian lynx along its path to extinction reconstructed with ancient DNA

2017

here is the tendency to assume that endangered species have been both genetically and demographically healthier in the past, so that any genetic erosion observed today was caused by their recent decline. The Iberian lynx (Lynx pardinus) suffered a dramatic and continuous decline during the 20th century, and now shows extremely low genome- and species-wide genetic diversity among other signs of genomic erosion. We analyze ancient (N = 10), historical (N = 245), and contemporary (N = 172) samples with microsatellite and mitogenome data to reconstruct the species' demography and investigate patterns of genetic variation across space and time. Iberian lynx populations transitioned from low but …

0106 biological sciences0301 basic medicineConservation of Natural ResourcesMetapopulationBiologyLincesExtinction Biological010603 evolutionary biology01 natural sciencesEndangered speciesgenetic erosion03 medical and health sciencesGenetic driftGenetic variationGeneticsAnimalsDNA AncientGenetic erosionancient DNAMolecular BiologyQH426Institut für Biochemie und BiologieDiscoveriesEcology Evolution Behavior and SystematicsPaleobiologíaGenetic diversityQLGenomeExtinctionAncient DNAEcologyQHEndangered SpeciesGenetic DriftGenetic VariationPaleogeneticsParque nacional de DoñanaSequence Analysis DNAIberian lynxGenéticahumanities030104 developmental biologyAncient DNAGenome MitochondrialLynxPaleogeneticsGenetic erosionpaleogeneticsMicrosatellite Repeats
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The role of the Strait of Gibraltar in shaping the genetic structure of the Mediterranean Grenadier, Coryphaenoides mediterraneus, between the Atlant…

2017

24 pages, 4 figures, 4 tables, supplementary information https://dx.doi.org/10.1371/journal.pone.0174988.-- Data Availability: The mtDNA COI sequences can be accessed at BOLD systems through the sample ID: ME-9911; ME-11972; ME-13727; GLF011. New mtDNA COI sequences can be accessed at GenBank by the accession numbers KY345206 - KY345398. GenBank accession numbers for close related species of C. mediterraneus are: Coryphaenoides striaturus - KX656427.1, KX656428.1; Coryphaenoides murray - KX656411.1, KX656410.1; Coryphaenoides carapinus - KX656382.1, KX656381.1; Coryphaenoides brevibarbis - KX656377.1, KX656376.1, KX656375.1. An alignment in fasta with all the haplotypes and respective frequ…

0106 biological sciences0301 basic medicineMediterranean climateLife CyclesHeredityPopulation geneticslcsh:MedicineArtificial Gene Amplification and ExtensionBiochemistryPolymerase Chain Reaction01 natural sciencesBathyal zoneLarvaeMediterranean sealcsh:ScienceAtlantic OceanPrincipal Component Analysiseducation.field_of_studyMultidisciplinaryGeographyMitochondrial DNANucleic acidsGenetic MappingGenetic structureResearch ArticleFish ProteinsGene FlowForms of DNAPopulationZoologyBiologyResearch and Analysis MethodsModels Biological010603 evolutionary biologyElectron Transport Complex IVEvolution Molecular03 medical and health sciencesMediterranean SeaGeneticsAnimalsComputer Simulation14. Life underwaterMolecular Biology TechniqueseducationMolecular BiologyGibraltarEvolutionary BiologyPopulation Biologylcsh:RGenetic VariationBiology and Life SciencesPaleontologyBayes TheoremDNAGenetic divergenceGadiformes030104 developmental biologyHaplotypesGenetic LociEarth SciencesBiological dispersallcsh:QPaleogeneticsPopulation GeneticsMicrosatellite RepeatsDevelopmental BiologyPLoS ONE
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Sedimentary Ancient DNA (sedaDNA) Reveals Fungal Diversity and Environmental Drivers of Community Changes throughout the Holocene in the Present Bore…

2021

Fungi are ecologically important in several ecosystem processes, yet their community composition, ecophysiological roles, and responses to changing environmental factors in historical sediments are rarely studied. Here we explored ancient fungal DNA from lake Lielais Svētiņu sediment throughout the Holocene (10.5 kyr) using the ITS metabarcoding approach. Our data revealed diverse fungal taxa and smooth community changes during most of the Holocene with rapid changes occurring in the last few millennia. More precisely, plankton parasitic fungi became more diverse from the Late Holocene (2–4 kyr) which could be related to a shift towards a cooler climate. The Latest Holocene (~2 kyr) showed …

0106 biological sciences0301 basic medicineMicrobiology (medical)paleoenvironmentEnvironmental changelake sedimentsBiology010603 evolutionary biology01 natural sciencesMicrobiologyArticlepaleoecology03 medical and health sciencesfungal biodiversityVirologysedimentary ancient DNAEcosystemlcsh:QH301-705.5HolocenepaleolimnologyEcologyfungiPlankton030104 developmental biologyAncient DNABoreallcsh:Biology (General)metabarcodingPaleoecologyenvironmental driversTerrestrial ecosystemITSpaleogeneticsMicroorganisms
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Rodents and palaeogenetics: new perspectives.

2008

10 pages; Rodents are the most diversified mammalian order (484 extant genera including 2277 species), and they have a worldwide distribution. Palaeontological, morphological and molecular data have greatly helped to resolve their systematics and evolutionary history. However, some discrepancies remain between palaeontologists and molecular biologists. New techniques in molecular biology, and especially in palaeogenetics, allow us to have direct access to the hereditary material of extinct organisms, and they can compensate for some morphological limits. Unfortunately, few studies are dealing with rodent palaeogenetics, despite the amount of museum and fossil material available. Here, we re…

0106 biological sciencesSystematicsZoologyBiology[SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics Phylogenetics and taxonomy010603 evolutionary biology01 natural sciencesRodentsGenetic diversity03 medical and health sciencesExtant taxonPhylogeneticsPalaeoparasitologyPhylogeny030304 developmental biology[ SDU.STU.PG ] Sciences of the Universe [physics]/Earth Sciences/Paleontology0303 health sciences[ SDE.BE ] Environmental Sciences/Biodiversity and Ecology[SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]Ancient DNAPhylochronologyGeneral EngineeringPaleogenetics[ SDV.GEN.GPO ] Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]Ancient DNA[SDE.BE]Environmental Sciences/Biodiversity and Ecology[SDU.STU.PG]Sciences of the Universe [physics]/Earth Sciences/Paleontology[ SDV.BID.SPT ] Life Sciences [q-bio]/Biodiversity/Systematics Phylogenetics and taxonomy
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Maternal DNA lineages at the gate of Europe in the 10th century AD

2018

Given the paucity of archaeogenetic data available for medieval European populations in comparison to other historical periods, the genetic landscape of this age appears as a puzzle of dispersed, small, known pieces. In particular, Southeastern Europe has been scarcely investigated to date. In this paper, we report the study of mitochondrial DNA in 10th century AD human samples from Capidava necropolis, located in Dobruja (Southeastern Romania, Southeastern Europe). This geographical region is particularly interesting because of the extensive population flux following diverse migration routes, and the complex interactions between distinct population groups during the medieval period. We suc…

0301 basic medicineEuropean PeopleremainsHeredityPopulation geneticslcsh:Medicinepopulation030105 genetics & heredityBiochemistryHaplogroupGeographical Locationscontaminationmitochondrial-dnaEthnicitieslcsh:SciencePhylogenymtDNA control regionPrincipal Component Analysiseducation.field_of_studyMultidisciplinaryGeographyHigh-Throughput Nucleotide SequencingPaleogeneticscontrol regionMitochondrial DNAEuropeNucleic acidsGenetic MappingPhylogeographyGeographyArchaeologyBiogeographyRomanian PeopleGenetic structurehistoryResearch ArticleMitochondrial DNAancient DNA mitochondrial DNA population genetics Romania Capidava medieval necropolisForms of DNAPopulationNear-EasternDNA MitochondrialBone and BonesWhite Peoplediversity03 medical and health sciencesgenetic affinitiesGeneticsHumanseducationEvolutionary BiologyBiology and life sciencesPopulation BiologyRomaniaEcology and Environmental Scienceslcsh:RPaleontologySequence Analysis DNADNAsequenceHistory MedievalPhylogeographyGenetics Population030104 developmental biologyHaplotypesEvolutionary biologyPeople and PlacesEarth SciencesHaplogroupsPopulation Groupingslcsh:QPaleogeneticsPopulation Genetics
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The population genomics of archaeological transition in west Iberia: Investigation of ancient substructure using imputation and haplotype-based metho…

2017

We analyse new genomic data (0.05–2.95x) from 14 ancient individuals from Portugal distributed from the Middle Neolithic (4200–3500 BC) to the Middle Bronze Age (1740–1430 BC) and impute genomewide diploid genotypes in these together with published ancient Eurasians. While discontinuity is evident in the transition to agriculture across the region, sensitive haplotype-based analyses suggest a significant degree of local hunter-gatherer contribution to later Iberian Neolithic populations. A more subtle genetic influx is also apparent in the Bronze Age, detectable from analyses including haplotype sharing with both ancient and modern genomes, D-statistics and Y-chromosome lineages. However, t…

0301 basic medicineMaleCancer ResearchHistoryHereditySteppePopulation geneticsGenetic LinkagePopulation geneticsStone AgeSocial SciencesQH426-470Population genomics0302 clinical medicineddc:590Databases GeneticGenetics(clinical)Sequencing dataGenetics (clinical)MigrationGenetics0303 health sciencesgeography.geographical_feature_categoryGenomeAncient DNAGeographyPaleogeneticsGeologyGenomicsCChumanitiesPositive selectionEuropeGenetic MappingPhylogeographyGeographyBiogeographyArchaeologyNeolithic PeriodlanguageFemaleResearch Articlelcsh:QH426-470GenotypeIntrogressionVariant GenotypesAdmixtureBiologyInsightsAssociation03 medical and health sciencesAgeBronze AgeGeneticsHumansGenetic variationQH426Molecular BiologyEcology Evolution Behavior and Systematics030304 developmental biologyEvolutionary BiologyChromosomes Human YHuman genomePopulation BiologyPortugalGenome HumanHaplotypeEcology and Environmental SciencesBiology and Life SciencesPaleontologyGenetic VariationGeologic TimeDnaSequence Analysis DNAArchaeologylanguage.human_languagePhylogeographylcsh:Genetics030104 developmental biologyAncient DNAGenetics PopulationHaplotypesEvolutionary biologyEarth SciencesIberiaPortuguesePaleogenetics030217 neurology & neurosurgeryImputation (genetics)Population GeneticsPLoS Genetics
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Gastrointestinal parasite burden in 4th-5th c. CE Florence highlighted by microscopy and paleogenetics

2021

The study of ancient parasites, named paleoparasitology, traditionally focused on microscopic eggs disseminated in past environments and archaeological structures by humans and other animals infested by gastrointestinal parasites. Since the development of paleogenetics in the early 1980s, few paleoparasitological studies have been based on the ancient DNA (aDNA) of parasites, although such studies have clearly proven their utility and reliability. In this paper, we describe our integrative approach for the paleoparasitological study of an ancient population from Florence in Italy, dated to the 4th-5th c. CE. The first stage consisted in the study of sediment samples from the pelvic area of …

0301 basic medicineMicrobiology (medical)Paleoparasitology030106 microbiologyPopulationZoologyContext (language use)Microbiology03 medical and health sciencesGeneticsAnimalsHumansTrichuriasisCitiesDicrocoeliumIntestinal Diseases ParasiticeducationMolecular BiologyHistory AncientEcology Evolution Behavior and SystematicsAscariasiseducation.field_of_studybiologyAscarisAscarisDicrocoelium dendriticumPaleogeneticsDicrocoeliasisbiology.organism_classificationTrichuris030104 developmental biologyInfectious DiseasesAncient DNAItalyAscaris lumbricoidesInfection, Genetics and Evolution
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Screening archaeological bone for palaeogenetic and palaeoproteomic studies.

2020

Funder: FP7 Ideas: European Research Council; funder-id: http://dx.doi.org/10.13039/100011199; Grant(s): 295729

1100Proteomics1300Social SciencesMarine and Aquatic Sciences01 natural sciencesBiochemistrySpectroscopy Fourier Transform InfraredLimnologyScreening method0303 health sciencesMultidisciplinaryAncient DNAChemistryFossilsQRFOS: Social sciencesNucleic acidsArchaeologyAttenuated total reflectionMedicinePhysical AnthropologyOrganic contentResearch Article1000010506 paleontologyScienceInfrared spectroscopyPaleoenvironmentsBone and Bones03 medical and health sciencesPaleoanthropologyGeneticsAnimalsHumansPaleolimnologyDNA AncientPaleozoology030304 developmental biology0105 earth and related environmental sciencesEcology and Environmental SciencesBiology and Life SciencesProteinsPaleontologyDNAArchaeologyEarth sciencesAncient DNAAnthropologyPaleobiologyPaleogeneticsCollagensPloS one
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Ancient DNA reveals prehistoric gene-flow from Siberia in the complex human population history of North East Europe.

2013

North East Europe harbors a high diversity of cultures and languages, suggesting a complex genetic history. Archaeological, anthropological, and genetic research has revealed a series of influences from Western and Eastern Eurasia in the past. While genetic data from modern-day populations is commonly used to make inferences about their origins and past migrations, ancient DNA provides a powerful test of such hypotheses by giving a snapshot of the past genetic diversity. In order to better understand the dynamics that have shaped the gene pool of North East Europeans, we generated and analyzed 34 mitochondrial genotypes from the skeletal remains of three archaeological sites in northwest Ru…

Gene Flow0106 biological sciencesCancer Researchlcsh:QH426-470GenotypePopulation DynamicsPopulationPopulation ModelingScandinavian and Nordic CountriesBiologySocial and Behavioral SciencesDNA Mitochondrial010603 evolutionary biology01 natural sciencesWhite PeopleHaplogroupRussiaCoalescent theory03 medical and health sciencesGeneticsHumanseducationBiologyMolecular BiologyGenetics (clinical)Ecology Evolution Behavior and Systematics030304 developmental biologyEvolutionary Biology0303 health scienceseducation.field_of_studyGenetic diversityPopulation BiologyGenetic VariationPaleogeneticsEuropeSiberialcsh:GeneticsBiological AnthropologyGenetics PopulationAncient DNAArchaeologyHaplotypesEvolutionary biologyAnthropologyGenome MitochondrialGene poolPopulation GeneticsResearch ArticleHuman mitochondrial DNA haplogroup
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