Search results for "Palsy"

Comparison of salivary cytokines levels among individuals with Down syndrome, cerebral palsy and normoactive

2019

Background Individuals with Down syndrome (DS) present increased susceptibility to infections and high prevalence of periodontal disease. The objective of this study is to evaluate the salivary concentrations of IL-1β, IL-6, IL-8, IL-10, TNFα and IL-12p70 of DS individuals and compare to cerebral palsy (CP) and normoactive patients (all with gingivitis). Material and Methods Twenty-two individuals with DS, 24 with CP and 22 normoactive participated in this cross-sectional study. Salivary flow rate, osmolality rate, Oral Hygiene Index, Gingival Index (GI) and salivary inflammatory markers IL-1β, IL-6, IL-8, IL-10, TNFα and IL-12p70 were evaluated. Shapiro-Wilks, Chi-square, ANOVA One-Way and…

Transitioning from adolescence to adulthood for young people living with cerebral palsy : a meta-ethnography

2020

Transitioning from adolescence to adulthood appears to be a challenging period for young people living with cerebral palsy. The aim of this review was to highlight the challenges that might be experienced during this period. A systematic search of the literature and meta-ethnographic review examined seven qualitative research papers providing a detailed synthesis in the form of three domains summarised as ‘meaningful preparation for transition’, ‘becoming empowered’, and, ‘overcoming vulnerability’. These inform a discussion which shows that adolescents living with cerebral palsy are not prepared adequately for adult life. Examination of the literature stimulates curiosity as to the nature …

Intervención terapéutica y coordinación familiar en los inicios comunicativos de un caso de atención temprana

2020

En este estudio de caso se aborda la intervención realizada en un centro de diagnóstico y atención temprana, a una alumna de dos años con hemiparesia lateral izquierda y dificultades en la manipulación y comunicación. Aplicando a lo largo de cuatro meses el sistema de Comunicación Total de Benson Schaeffer con el apoyo del método TEACCH, se pretende superar las graves limitaciones comunicativas de la alumna. El procedimiento metodológico utilizado es mixto y las técnicas de investigación empleadas son la aplicación de un test estandarizado, la entrevista, los registros de observación y el análisis documental. A partir del test cumplimentado por la madre que establece la evaluación inicial d…

Persistent idiopathic unilateral hypoglossal nerve palsy.

1998

DCTN1 mutation analysis in Italian patients with PSP, MSA, and DLB

2020

Abstract DCTN1 encodes the largest subunit of dynactin complex essential in the retrograde axonal transport and cytoplasmic transport of vesicles; mutations in DCTN1 have been reported predominantly in individuals with Perry syndrome and, recently, in patients with progressive supranuclear palsy. Our genetic screening of DCTN1 in 79 patients with progressive supranuclear palsy, 100 patients with multiple system atrophy, and 28 patients with dementia with Lewy bodies from Italy revealed only synonymous and intronic variants, suggesting that DCTN1 mutations do not have a key role in the development of atypical parkinsonism in the Italian population.

Dry needling technique decreases spasticity and improves general functioning in incomplete spinal cord injury: A case report

2018

Context: Spasticity in neurological disorders (i.e. stroke patients and cerebral palsy) is positively improved by dry needling. However, reports are scarce regarding the potential effects of dry needling in reducing spasticity and improving functionality in patients with an incomplete spinal cord injury. The aim of this case report was to study the immediate, short-term effects of dry needling treatment (10 weeks) on spasticity, dynamic stability, walking velocity, self-independence, and pain in a single patient with an incomplete spinal cord injury. Findings: The dry needling treatment resulted in immediate, short-time effects on basal spasticity in the upper (reduction from 2 to 0 point m…

Dental treatment under general anesthesia in a group of patients with cerebral palsy and a group of healthy pediatric patients

2014

This is a comparative study between two groups, one of healthy children and the other of children with cerebral palsy, which underwent dental treatment under general anesthesia at Hospital Sant Joan de Déu Barcelona. The purpose of the study was to compare and determine oral pathology, frequency, severity and postoperative complications in pediatric patients with and without an underlying disease which undergo a dental treatment under general anesthesia. Key words:General anesthesia, cerebral palsy, pediatric patients.

Error Detection and Response Adjustment in Youth With Mild Spastic Cerebral Palsy

2013

This study evaluated the brain activation state during error making in youth with mild spastic cerebral palsy and a peer control group while carrying out a stimulus recognition task. The key question was whether patients were detecting their own errors and subsequently improving their performance in a future trial. Findings indicated that error responses of the group with cerebral palsy were associated with weak motor preparation, as indexed by the amplitude of the late contingent negative variation. However, patients were detecting their errors as indexed by the amplitude of the response-locked negativity and thus improved their performance in a future trial. Findings suggest that the con…

Genetic linkage of autosomal dominant progressive supranuclear palsy to 1q31.1

2005

Progressive supranuclear palsy (PSP) is a disorder of unknown pathogenesis. Familial clusters of PSP have been reported related to mutations of protein tau. We report the linkage of a large Spanish family with typical autosomal dominant PSP to a new locus in chromosome 1. Four members of this family had typical PSP, confirmed by neuropathology in one case. At least five ancestors had similar disease. Other members of the family have incomplete phenotypes. The power of the linkage analysis was increased by detecting presymptomatic individuals with 18F-fluoro-dopa and 18F-deoxyglucose positron emission tomography. We screened the human genome with 340 polymorphic markers and we enriched the a…

Persistent idiopathic hypoglossal nerve palsy: A motor neuron disease-mimic syndrome?

2014

Unilateral isolated hypoglossal nerve palsy (IHNP) is a condition (1–7) usually symptomatic of a pathology of the skull base (6,8). In rare cases, IHNP remains of unknown aetiology and is classifie...