Search results for "Pancrea"

showing 10 items of 814 documents

Spatial and temporal dynamics of innervation during the development of fetal human pancreas.

2008

The delineation of pancreatic nerve innervations during fetal life may contribute to our understanding of pancreatic pain modalities after birth. The aim of this study was to characterize the spatial and temporal distribution of nerve structures in the human pancreas throughout gestation. Computer-based image morphometry with piecewise polynomial interpolation analysis was performed to quantify nervous structures in the head, body and tail of the pancreas. Nerve structures were detected by automatic immunostaining techniques using a polyclonal antibody against two S-100 proteins that reacts strongly with human S100A and B that are detected in Schwann cells. Immunoreactivity was found in the…

Pathologymedicine.medical_specialtyFetusGeneral NeuroscienceOntogenyS100 ProteinsAnatomyBiologyImmunohistochemistrySuperior mesenteric plexusmedicine.nervemedicine.anatomical_structureHuman pancreasFetusImaging Three-DimensionalParenchymamedicineImage Processing Computer-AssistedGestationHumanspancreasPancreasImmunostaining
researchProduct

Diabetes screening by telecentric digital holographic microscopy

2015

Diabetes is currently the world's fastest growing chronic disease and it is caused by deficient production of insulin by the endocrine pancreas or by abnormal insulin action in peripheral tissues. This results in persistent hyperglycaemia that over time may produce chronic diabetic complications. Determination of glycated haemoglobin level is currently the gold standard method to evaluate and control sustained hyperglycaemia in diabetic people. This measurement is currently made by high-performance liquid chromatography, which is a complex chemical process that requires the extraction of blood from the antecubital vein. To reduce the complexity of that measurement, we propose a fully-optica…

Pathologymedicine.medical_specialtyHistologybusiness.industryAntecubital veinInsulinmedicine.medical_treatment030209 endocrinology & metabolismmedicine.disease01 natural sciencesPathology and Forensic Medicine010309 optics03 medical and health sciences0302 clinical medicinemedicine.anatomical_structureDiabetes screeningDiabetes mellitus0103 physical sciencesMicroscopymedicineDigital holographic microscopyPancreasbusinessMass screeningBiomedical engineeringJournal of Microscopy
researchProduct

Pancreas and Cystic Fibrosis: The Implications of Increased Survival in Cystic Fibrosis

2007

Background: In acute pancreatitis (AP), pancreatic necrosis (PN) is an important local complication that can be identified by means of contrast-enhanced computed tomography (CECT).

Pathologymedicine.medical_specialtyNecrosisHepatologybiologybusiness.industryEndocrinology Diabetes and MetabolismfungiC-reactive proteinGastroenterologyfood and beveragesmedicine.diseasemedicinebiology.proteinTechnetium Tc 99m ExametazimePancreatitisAcute pancreatitisIn patientmedicine.symptombusinessComplicationTechnetium-99mPancreatology
researchProduct

Laser fragmentation of pancreatic duct stones using a rhodamine laser with an automatic stone-tissue detection system. Basic in-vitro studies

1997

OBJECTIVES The aim of our study was to examine the suitability of a rhodamine 6G laser with an integrated stone-tissue detection system (STDS) for fragmenting pancreatic stones. METHODS A total of 64 pancreatic duct stones were measured for weight, diameter, main chemical components and in some cases for their computerized tomography density. Recognition of all stones was checked with the standard STDS or a prototype version. Number of fragmentation pulses, total fragmentation energies and correlation with the individual stone parameters were determined. The quality of the tissue-detection mode was evaluated in postmortem pancreata. RESULTS The standard STDS detected only 45% of the pancrea…

Pathologymedicine.medical_specialtyPancreatic diseasemedicine.medical_treatmentIn Vitro TechniquesLithotripsySensitivity and SpecificityCalculilaw.inventionRhodamine 6GRhodaminechemistry.chemical_compoundlawmedicineHumansPancreatic stonesFragmentation (cell biology)Pancreatic ductHepatologyRhodaminesbusiness.industryPancreatic DuctsGastroenterologyPancreatic DiseasesEquipment DesignLithotripsy LaserLasermedicine.diseasemedicine.anatomical_structurechemistryTomography X-Ray ComputedNuclear medicinebusinessEuropean Journal of Gastroenterology & Hepatology
researchProduct

Inflammatory and tumor-like lesions of the pancreas

2020

Summary Inflammatory/tumor-like lesions of the pancreas represent a heterogeneous group of diseases that can variably involve the pancreatic gland determining different signs and symptoms. In the category of inflammatory/tumor-like lesions of the pancreas, the most important entities are represented by chronic pancreatitis, which includes alcoholic, obstructive and hereditary pancreatitis, paraduodenal (groove) pancreatitis, autoimmune pancreatitis, lymphoepithelial cyst, pancreatic hamartoma and intrapancreatic accessory spleen. An in-depth knowledge of such diseases is essential, since they can cause severe morbidity and may represent a potential life-threatening risk for patients. Furthe…

Pathologymedicine.medical_specialtyautoimmune pancreatitiReviewSettore MED/08 - Anatomia PatologicaAccessory spleenparaduodenal pancreatitisPathology and Forensic MedicineDiagnosis Differentialchronic pancreatitisPancreatitis Chronicparaduodenal pancreatitis.groovemedicineHamartomaPancreasAutoimmune pancreatitisHereditary pancreatitisbusiness.industrymedicine.diseaseautoimmune pancreatitisPancreatic Neoplasmspancreatic pathologymedicine.anatomical_structurePancreatitisSevere morbidityPancreatitischronic pancreatitiDifferential diagnosisPancreasbusinessautoimmune pancreatitis; chronic pancreatitis; groove; pancreatic pathology; paraduodenal pancreatitis
researchProduct

Pancreatitis autoinmune: pseudotumor inflamatorio, afectación multifocal, hipertensión portal y evolución a largo plazo

2008

Autoimmune pancreatitis is a recently characterized disease that still constitutes a diagnostic challenge, especially regarding differential diagnosis from neoplasia. Long-term outcome is poorly known. We herein report a case of a patient with autoimmune pancreatitis and 14 years of follow-up, and show its clinical, biochemical, and morphological characteristics. A 54-year-old female presented with obstructive jaundice and abdominal tenderness, as well as a mass at the pancreatic head on a CT scan, suggestive of pancreatic neoplasia. Surgery showed an increase of the whole pancreas, malignancy was intraoperatively ruled out, and a cholecystectomy and choledochoduodenostomy were carried out.…

Pathologymedicine.medical_specialtybusiness.industryGastroenterologyGeneral MedicineJaundicemedicine.diseaseRetroperitoneal fibrosismedicine.anatomical_structureEsophageal varicesmedicinePortal hypertensionPancreatitismedicine.symptomDifferential diagnosisPancreasbusinessAutoimmune pancreatitisRevista Española de Enfermedades Digestivas
researchProduct

Ultrasonic demonstration of small pancreatic islet cell tumors.

1982

In three patients real-time sonography successfully localized small pancreatic islet cell tumors measuring 7, 8, and 17 mm in size. Ultrasound is suggested as the initial radiologic examination for localization of endocrine pancreatic tumors. If ultrasound is negative or equivocal, computerized tomography, arteriography, and pancreatic venous sampling are indicated.

Pathologymedicine.medical_specialtybusiness.industryRadiologic examinationUltrasoundMiddle Agedmedicine.diseaseAdenoma Islet CellPancreatic venous samplingPancreatic Neoplasmsmedicine.anatomical_structureEndocrinologyInternal medicinePancreatic islet cell tumorsMedicineHumansRadiology Nuclear Medicine and imagingUltrasonic sensorFemaleInsulinomaEndocrine pancreatic tumorsbusinessPancreasInsulinomaUltrasonographyJournal of clinical ultrasound : JCU
researchProduct

Quiste broncogénico de localización excepcional que simula una tumoración pancreática

2010

We report a 37-year woman with a history of acute cholangitis in whom a bronchogenic cyst was misdiagnosed as a pancreatic neoplasm on the basis of the clinical and radiological findings. Infradiaphragmatic bronchogenic cysts are rare and can sometimes mimic a pancreatic carcinoma.

Pathologymedicine.medical_specialtybusiness.industryparasitic diseasesBronchogenic cystMedicineRadiology Nuclear Medicine and imagingPancreatic carcinomabusinessmedicine.diseaseRadiología
researchProduct

Determination of Human Granulocyte Elastase by the Immunoactivation Method on the Hitachi® 717 Automated Analyser

1991

This paper describes a fully mechanized homogeneous immunoassay using the immunoactivation method for the rapid and specific determination of human granulocyte elastase (EC 3.4.21.37) in plasma. The method uses anti-elastase antibody fragments from sheep, conjugated to horseradish peroxidase. These enzyme-antibody conjugates bind to the elastase-alpha 1-proteinase inhibitor complex present in plasma. A separate sample blank with non-specific sheep antibody fragments conjugated to horseradish peroxidase corrects for errors introduced by the sample matrix. Measurements were performed with the clinical chemistry analyser Hitachi 717. A single determination can be performed in 10 min, requiring…

Pathologymedicine.medical_specialtyeducationClinical BiochemistryEnzyme-Linked Immunosorbent AssayGranulocyteHorseradish peroxidaseReference ValuesBlood plasmamedicineHumansAutomated analyserAutoanalysisChromatographyPancreatic Elastasebiologymedicine.diagnostic_testBiochemistry (medical)ElastaseGeneral Medicinemedicine.anatomical_structureImmunoassaybiology.proteinLeukocyte ElastaseQuantitative analysis (chemistry)ConjugateClinical Chemistry and Laboratory Medicine
researchProduct

PO-0359 How To Select The Sweat Test Candidate. 10 Years Of Experience In Screening For Cystic Fibrosis In Children

2014

Background Sweat test (ST) remains gold standard in cystic fibrosis (CF) diagnosis. Alarm symptoms are age-related. Aims Retrospective review of cases subjected to ST. Methods Patients were selected by paediatricians, neonatologists, surgeons, based on suggestive symptoms, personal (PH) and familial history (FH). Inclusion criteria: for 0–1 month age group, patients with PH of atelectasis, meconium ileus, intussusception; 1–12 months, recurrent wheezing (RW), failure to thrive (FTT); 1–5 years, previous group symptoms, plus chronic cough/diarrhoea; >5 years, 1–5 years symptoms, plus recurrent pancreatitis/sinusitis. For all age, patients with PH of salty taste of sweat (STS), salt wasting s…

Pediatricsmedicine.medical_specialtymedicine.diagnostic_testbusiness.industryAtelectasismedicine.diseaseCystic fibrosisChronic coughRecurrent pancreatitisPediatrics Perinatology and Child HealthFailure to thrivemedicinePancreatitismedicine.symptombusinessSinusitisSweat testArchives of Disease in Childhood
researchProduct