Search results for "Pandemics"

showing 10 items of 522 documents

Management of severe asthma during the first lockdown phase of SARS-CoV-2 pandemic: Tips for facing the second wave.

2022

SARS-CoV-2 pandemic has contributed to implement telemedicine, allowing clinicians to follow the patient remotely, therefore minimizing the risk of any exposure to positive COVID-19 patients. We summarize the approaches adopted to treat and monitor severe asthmatic patients during the lockdown phase of the pandemic. Our experience supports the strategy that every effort should be made to minimize patient contact with the health-care system, planning a pathway that allows patients to receive appropriate medical care and continue the biological therapies, thus preventing the loss of disease control and acute severe exacerbations.

Pulmonary and Respiratory MedicineCOVID-19 Health-care management Respiratory symptoms Severe asthmasevere asthmamedicine.medical_specialtyTelemedicineCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Severe asthmaSettore MED/10 - Malattie Dell'Apparato RespiratorioPhase (combat)ArticlePandemicmedicineAsthmatic patientHumansPharmacology (medical)Intensive care medicinehealth-care managementPandemicsbusiness.industrySARS-CoV-2Biochemistry (medical)Patient contactrespiratory symptomsCOVID-19AsthmaCommunicable Disease ControlbusinessPulmonary pharmacologytherapeutics
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Sleep apnoea management in Europe during the COVID-19 pandemic: data from the European Sleep Apnoea Database (ESADA)

2020

Sleep disordered breathing (SDB) is highly prevalent with a male to female predominance of two to one, and is more common in middle-aged and elderly subjects [1]. Affected patients often present with comorbidities such as obesity, cardiovascular disease (systemic hypertension, heart failure, atrial fibrillation), and diabetes mellitus Type II [2]. The strong overlap between the profile for SDB patients and the identified risk factors for adverse outcomes of COVID-19 infection that include age, male gender, and cardio-metabolic comorbidity [3] suggest that SDB patients may benefit from effective therapy if confronted with COVID-19 infection [4].

Pulmonary and Respiratory MedicinePediatricsmedicine.medical_specialtyDatabases FactualPolysomnographymedicine.medical_treatmentPneumonia ViralPersonnel Staffing and SchedulingPolysomnographyDiseaseCovidsleep laboratoryBetacoronavirus03 medical and health sciencesSleep Apnea SyndromeSleep Apnea Syndromes0302 clinical medicineSurveys and Questionnairesmental disordersResearch LettermedicineHumanscardiovascular diseases030212 general & internal medicineContinuous positive airway pressurePandemicsSleep Medicine SpecialtyContinuous Positive Airway Pressuremedicine.diagnostic_testCoronavirus InfectionSARS-CoV-2business.industrySleep apneaCOVID-19Atrial fibrillationmedicine.diseaseComorbidityObesityTelemedicineEuropeSleep Medicine Specialty030228 respiratory systemHeart failureCoronavirus InfectionsbusinessDelivery of Health CaremanagementEuropean Respiratory Journal
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VENTILATOR CONFIGURATION IN CHILDREN ON LONG TERM HOME VENTILATION DURING THE COVID19 PANDEMIC

2021

Pulmonary and Respiratory Medicinemedicine.medical_specialty2019-20 coronavirus outbreakVentilators MechanicalRC705-779Coronavirus disease 2019 (COVID-19)business.industrySARS-CoV-2Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)long term ventilationCOVID-19Home Care ServicesArticleTerm (time)Home ventilationDiseases of the respiratory systemEmergency medicinePandemicmedicineHumansbusinessChildPandemicsLong term ventilationPulmonology
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A review of venous thromboembolism in COVID‐19: A clinical perspective

2021

Abstract Coronavirus disease‐19 (COVID‐19) started in Wuhan, China in December 2019 and spread to all around the world in a short period of time. Hospitalized patients with COVID‐19 mostly could suffer from an abnormal coagulation activation risk with increased venous thrombosis events and a poor clinical course. The reported incidence rates of thrombotic complications in hospitalized COVID‐19 patients vary between 2.6 and 85% (both in non‐critically ill and critically ill patients). The risk of venous thromboembolism is not known in non‐hospitalized patients with COVID‐19. There are numerous studies and guidelines for administration of thromboprophylaxis for COVID‐19 cases. All hospitalize…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Hospitalized patientsCritical IllnessGlobal Health03 medical and health sciences0302 clinical medicineCOVID‐19medicineHumansImmunology and AllergyGenetics(clinical)030212 general & internal medicineanticoagulationIntensive care medicinePandemicsContraindicationGenetics (clinical)Critical perspectiveSARS-CoV-2business.industryCritically illIncidenceCOVID-19Venous ThromboembolismOriginal Articlesmedicine.diseasemortalityLMWHVenous thrombosis030228 respiratory systemOriginal Articlevenous thrombosisbusinessVenous thromboembolismThrombotic complicationThe Clinical Respiratory Journal
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The impact of SARS-COV2 pandemic on the management oF IPF patients: Our narrative experience

2021

Abstract Background The SARS-CoV-2 pandemic has changed the health-care systems around the world in a remarkable way. We describe the strategies adopted to cope with the limitations imposed by the pandemic to the access to health care by patients diagnosed with idiopathic Pulmonary Fibrosis (IPF). Material and methods We conducted a retrospective observational analysis including IPF patients under antifibrotic drugs (nintedanib and pirfenidone) that accessed to the Outpatient clinic of the University of Palermo, Italy. Patients received a phone number and an email address in case of any urgency and a virtual meeting was settled up monthly. Results 40 patients (M/F: 30/10) were followed up, …

Pulmonary and Respiratory Medicinemedicine.medical_specialtyPyridonesCOVID-19 IPF Pulmonary fibrosis SARS-CoV-2DiseaseSettore MED/10 - Malattie Dell'Apparato RespiratorioSARS-CoV-2 severe acute respiratory syndrome coronavirus 2ArticlePulmonary fibrosis03 medical and health sciencesIdiopathic pulmonary fibrosischemistry.chemical_compound0302 clinical medicineED Emergency departmentInternal medicinePulmonary fibrosisPandemicmedicineOutpatient clinicHumansPharmacology (medical)030212 general & internal medicineIPF Idiopathic Pulmonary FibrosisPandemicsRetrospective StudiesCOVID-19 Coronavirus disease 2019business.industrySARS-CoV-2Biochemistry (medical)ARDS adult respiratory distress syndromeCOVID-19Emergency departmentPirfenidonemedicine.diseaseIdiopathic Pulmonary FibrosisIPF030228 respiratory systemchemistryHRCT High-resolution chest tomographyRNA ViralNintedanibbusinessPulmonary fibrosimedicine.drug
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Severe asthma and COVID-19: lessons from the first wave

2020

Objective: Severe asthma is considered a risk factor for SARS-Coronavirus 2 (SARS-CoV-2) infection but scientific evidences are lacking. Methods: we performed a literature search and review based on PubMed database national, international recommendations as well as papers on severe asthmatic patients and their management during SARS-CoV-2 pandemic. Results: the majority of international recommendations, expert panels and editorials provide indications about management of severe asthmatic patients. No published studies evaluated the effects of biologic agents on severe asthmatic patients during SARS-CoV-2 pandemic. Conclusions: the relationship between SARS-CoV-2 and asthma is variable world…

Pulmonary and Respiratory Medicinesevere asthma2019-20 coronavirus outbreakmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)biologic agentsvirusesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Severe asthmaInhaled corticosteroidsSettore MED/10 - Malattie Dell'Apparato Respiratoriooral corticosteroids03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicinemedicineHumansImmunology and AllergyAnti-Asthmatic AgentsPediatrics Perinatology and Child Health030212 general & internal medicineRisk factorskin and connective tissue diseasesPandemicsAsthmabusiness.industryAsthma; biologic agents; COVID-19; inhaled corticosteroids; oral corticosteroids; SARS-CoV-2; severe asthmaSARS-CoV-2fungiPatient AcuityAsthma biologic agents COVID-19 inhaled corticosteroids oral corticosteroids SARS-CoV-2 severe asthmaCOVID-19medicine.diseaseAsthmarespiratory tract diseasesBiologic Agentsbody regions030228 respiratory systemPractice Guidelines as TopicPediatrics Perinatology and Child Healthinhaled corticosteroidsbusiness
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Quality of life and fear of COVID-19 in 2600 baccalaureate nursing students at five universities : a cross-sectional study

2021

Abstract Background The COVID-19 pandemic has caused significant disruptions in the implementation of programs across educational institutions. Nursing students, being both young adults and by practical training, part of the health care system, may be particularly vulnerable during the COVID-19 pandemic. The purpose of this study was to explore the associations between self-reported fear of COVID-19, general health, psychological distress and overall quality of life (QoL) in a sample of Norwegian baccalaureate nursing students compared to reference data. Methods The survey targeted baccalaureate nursing students from five universities in February 2021. An electronic questionnaire consisted …

Quality of lifeMaleCoronavirus disease 2019 (COVID-19)UniversitiesCross-sectional studyComputer applications to medicine. Medical informaticsR858-859.7NorwegianPsychological distressGeneral healthYoung AdultLife qualityQuality of life:Medisinske Fag: 700 [VDP]Health careMedicineHumansYoung adultCOVID-19 fearPandemicslivskvalitetbusiness.industrySARS-CoV-2sykepleiestudenterResearchMultilevel modelPublic Health Environmental and Occupational HealthCOVID-19Fear of COVID-19General MedicineFearlanguage.human_languagePeer reviewCross-Sectional StudiesVDP::Medisinske Fag: 700::Helsefag: 800languageFemaleStudents NursingNursing studentsbusinessClinical psychology
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How COVID-19 kick-started online learning in medical education-The DigiMed study.

2021

Background The coronavirus disease 2019 (COVID-19) pandemic led to far-reaching restrictions of social and professional life, affecting societies all over the world. To contain the virus, medical schools had to restructure their curriculum by switching to online learning. However, only few medical schools had implemented such novel learning concepts. We aimed to evaluate students’ attitudes to online learning to provide a broad scientific basis to guide future development of medical education. Methods Overall, 3286 medical students from 12 different countries participated in this cross-sectional, web-based study investigating various aspects of online learning in medical education. On a 7-…

QuestionnairesViral DiseasesInternet en l'ensenyamentEpidemiologySocial SciencesActituds dels alumnesLearning and MemoryMedical ConditionsSociologyPsychological AttitudesPandemicMedicine and Health SciencesPsychologySocial isolationComputer Networksmedia_commonMultidisciplinaryEducation MedicalQAttendanceRFlexibility (personality)Ensenyament a distànciaInternet in educationInfectious DiseasesResearch DesignLecturesMedicinemedicine.symptomPsychologyResearch ArticleComputer and Information SciencesMedicinamedia_common.quotation_subjectScienceMEDLINEResearch and Analysis MethodsLikert scaleEducationDistance educationEducation DistanceHuman LearningmedicineHumansLearningQuality (business)ddc:610CurriculumPandemicsMedical educationInternetSurvey ResearchCognitive PsychologyCOVID-19Biology and Life SciencesCovid 19Student attitudesAttitudeMedical EducationCognitive ScienceMedical HumanitiesNeurosciencePloS one
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Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of virus isolates

2021

Due to the widespread of the COVID-19 pandemic, the SARS-CoV-2 genome is evolving in diverse human populations. Several studies already reported different strains and an increase in the mutation rate. Particularly, mutations in SARS-CoV-2 spike-glycoprotein are of great interest as it mediates infection in human and recently approved mRNA vaccines are designed to induce immune responses against it. We analyzed 1,036,030 SARS-CoV-2 genome assemblies and 30,806 NGS datasets from GISAID and European Nucleotide Archive (ENA) focusing on non-synonymous mutations in the spike protein. Only around 2.5% of the samples contained the wild-type spike protein with no variation from the reference. Among…

RNA virusesMutation rateCoronavirusesEpidemiologyMolecular biologyT-LymphocytesMutantGene Identification and Analysismedicine.disease_causeGenomeWhite Blood CellsDatabase and Informatics MethodsSequencing techniquesMutation RateAnimal CellsDNA sequencingPathology and laboratory medicineGeneticsMutationMultidisciplinaryT CellsMicrobial MutationQRHigh-Throughput Nucleotide SequencingGenomicsMedical microbiologyVirusesSpike Glycoprotein CoronavirusMedicineSARS CoV 2PathogensCellular TypesTranscriptome AnalysisSequence AnalysisResearch ArticleNext-Generation SequencingSARS coronavirusBioinformaticsImmune CellsScienceImmunologyProtein domainSequence alignmentGenomicsGenome ViralBiologyMicrobiologyAntibodiesDNA sequencingProtein DomainsGeneticsmedicineHumansMutation DetectionPandemicsMedicine and health sciencesBlood CellsBiology and life sciencesSARS-CoV-2OrganismsViral pathogensComputational BiologyCOVID-19Cell BiologyGenome AnalysisMicrobial pathogensResearch and analysis methodsMolecular biology techniquesMutationSequence AlignmentPLOS ONE
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Epidemiological characteristics of COVID-19 cases in non-Italian nationals in Sicily: identifying vulnerable groups in the context of the COVID-19 pa…

2022

As in other parts of the world, undocumented migrants in Italy suffer worse health status due to their immigration enforcement situation and other vulnerabilities such as precarious illegal jobs, exploitation and abuse or barriers to higher education, with higher prevalence of chronic noncommunicable diseases. The COVID-19 pandemic, as other pandemics, has not affected everyone equally. The undocumented was one of the most affected groups with regard to hospitalization rates and mortality worldwide. Sicily is one of the gates of entrance to Europe for migrants and asylum seekers from Africa and Asia. Herein, we described the epidemiological characteristics of COVID-19 cases in Sicily to com…

Refugeesaccess to health care; vulnerable populations; migrants; refugee and asylum seeker health care; inequalities in health and health care; health inequalitiesHealth Toxicology and Mutagenesisrefugee and asylum seeker health carePublic Health Environmental and Occupational HealthVulnerable populationsInequalities in health and health careinequalities in health and health careCOVID-19vulnerable populations.MigrantsRefugee and asylum seeker health careHospitalizationhealth inequalitiemigrantItalyAccess to health careaccess to health careHumansPandemicsSicilyHealth inequalities
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