Search results for "Paragonimus"
showing 4 items of 4 documents
Morphological and molecular characterization of Paragonimus caliensis Little, 1968 (Trematoda: Paragonimidae) from Medellin and Pichinde, Colombia
2018
Paragonimiasis is a subacute to chronic inflammatory granulomatous lung disease caused by the genus Paragonimus. In Latin America Paragonimus mexicanus Miyazaki & Ishii, 1968 is the only confirmed species to cause human infections. Paragonimus caliensis Little, 1968 is an uncommon species often regarded as a synonym of P. mexicanus. Recently, the study of two types of Paragonimus metacercariae from Costa Rica has provided new molecular and morphological evidence that P. caliensis is a separate species from P. mexicanus. In the present study, molecular, morphological and phylogenetic tools have been used to characterize two populations of Paragonimus located at west of Medellin, Antioquia an…
Fasciola spp: Mapping of the MF6 epitope and antigenic analysis of the MF6p/HDM family of heme-binding proteins
2017
MF6p/FhHDM-1 is a small cationic heme-binding protein which is recognized by the monoclonal antibody (mAb) MF6, and abundantly present in parenchymal cells and secreted antigens of Fasciola hepatica. Orthologs of this protein (MF6p/HDMs) also exist in other causal agents of important foodborne trematodiasis, such as Clonorchis sinensis, Opisthorchis viverrini and Paragonimus westermani. Considering that MF6p/FhHDM-1 is relevant for heme homeostasis in Fasciola and was reported to have immunomodulatory properties, this protein is expected to be a useful target for vaccination. Thus, in this study we mapped the epitope recognized by mAb MF6 and evaluated its antigenicity in sheep. The sequenc…
Detection of multiple species of humanParagonimusfrom Mexico using morphological data and molecular barcodes
2013
Paragonimus mexicanus is the causal agent of human paragonimiasis in several countries of the Americas. It is considered to be the only species of the genus present in Mexico, where it is responsible for human infection. Through the investigation of P. mexicanus specimens from several places throughout Mexico, we provide morphological, molecular and geographical evidence that strongly suggests the presence of at least three species from this genus in Mexico. These results raise questions regarding the diagnosis, treatment, prophylaxis and control of human paragonimiasis in Mexico. We also provide a brief discussion regarding biodiversity inventories and the convenience of providing molecula…
Caracterización morfológica y molecular de Paragonimus caliensis Little 1968 y Paragonimus mexicanus Miyazaki & Ishii 1968 (Digenea: Paragonimidae) e…
2018
La paragonimiasis es una enfermedad pulmonar granulomatosa inflamatoria crónica causada por trematodos del género Paragonimus. En América Latina, P. mexicanus Miyazaki & Ishii 1968 es la única especie confirmada que causa infecciones humanas. Paragonimus caliensis Little 1968, es una especie poco común a menudo considerada sinónima junior de P. mexicanus. Recientemente, el estudio molecular y morfológico de dos tipos de metacercarias de Paragonimus en Costa Rica proporcionó la evidencia de que P. caliensis es una especie separada de P. mexicanus. En el presente estudio se utilizaron herramientas moleculares, filogenéticas y morfológicas para caracterizar cuatro poblaciones de Paragonimus en…