Search results for "Patches"
showing 9 items of 19 documents
In vitrouptake of lysozyme-loaded liposomes coated with chitosan biopolymer as model immunoadjuvants
2009
Chitosan binds to negatively charged soy lecithin liposomes by an electrostatic interaction driven by its cationic amino group. This interaction allows developing stable coated vesicles suitable as a targeted carrier and controlled release system for drugs and vaccines. In this work, we studied the effect of chitosan-coated liposomes on the uptake and antigen presentation of hen egg-white lysozyme (HEL) in Peyer's patches peritoneal macrophages isolated from mice. Chitosan-coated liposomes were characterized according to size, zeta potential, and antigen-loading and release properties. Results showed an increase in the positive net charge and size of the liposomes as the concentration of ch…
The “mode” of lymphocyte extravasation through HEV of Peyer's patches and its role in normal homing and inflammation
2007
The mode of lymphocyte transendothelial migration in the postcapillary high endothelial venules (HEVs) of Peyer's patches during normal homing and acute inflammation in the guinea pig was studied. It is common opinion that the lymphocyte transendothelial passage from the blood stream into the extravasal lymphoid tissue calls for a multistep process of endothelial and lymphocyte molecules favoring tethering, rolling, activation, arrest and its firm adhesion to the endothelial luminal surface. Ultrastructural serial pictures and the three-dimensional reconstruction of HEVs with lymphocytes during different moments of their transmigration through the endothelial wall enabled us to demonstrate …
Distribution and phenotype of rotavirus-specific B cells induced during the antigen-driven primary response to 2/6 virus-like particles administered …
2007
AbstractSelection of mucosal sites is an important step in mucosal vaccine development. The intrarectal (IR) route represents an alternative to the oral route of immunization; nevertheless, immune responses induced by this route are not well defined. Here, we studied the early primary B cell response (induction, homing, and phenotype) induced by IR immunization with rotavirus (RV)-2/6 virus-like particles (VLP). Using flow cytometry, we traced RV-specific B cells in different lymphoid tissues and analyzed the expression of α4β7 and CCR9, which are important receptors for homing to the gut, as well as CD5, a marker expressed by B1-a cells, which are a major source of natural antibodies. We o…
A fast BEM for the analysis of plates with bonded piezoelectric patches
2010
In this paper a fast boundary element method for the elastodynamic analysis of 3D structures with bonded piezoelectric patches is presented. The elastodynamic analysis is performed in the Laplace domain and the time history of the relevant quantities is obtained by inverse Laplace transform. The bonded patches are modelled using a semi-analytical state-space variational approach. The computational features of the technique, in terms of required storage memory and solution time, are improved by a fast solver based on the use of hierarchical matrices. The presented numerical results show the potential of the technique in the study of structural health monitoring (SHM) systems.
Mechanisms involved in spatial and temporal mobility of disease patches caused by Rhizoctonia solani in sugar beet field : Induction of antagonists w…
2008
National audience; Rhizoctonia solani AG 2-2 causes damping-off and root rot on sugar beet in patches that are highly mobile both on spatial and temporal scales. They never occur in the same place where they were in the previous season. The aim of the present study was to uncover the mechanisms underlying the dynamics of disease patches. It was observed that soil inoculum potential was higher within diseased patch than in healthy area. However, the dormant pathogen in healthy area was stimulated by addition of buckwheat meal more than that in diseased patch. In addition soil from diseased area was more suppressive towards the disease. We did not observe significant differences in bacterial …
Modélisation numérique d'assemblages collés : application à la réparation de structures en composites
2013
This study is one part of a program of research with regard to the repair of composite structure with extern bonded-patches. The principal objectives of this program are, on one side, the identification of all the factors susceptible to influence the long-term performance of this type of repair, on the other, to determine the extent to which the use of such assemblage can be proved to be an optimal solution. The conception of such a system needs essentially the development of a tool of simulation and of robust prediction because various mechanisms of damage can take place in a very complex way and the final fracture of the system arise from the propagation of damage zones. This study consis…
Thermomechanical Behavior of Beams Covered with Viscoelastic Patches
2018
International audience; Infrared thermography is a non-destructive test method based on infrared measurement that provides a luminance map of the thermal scene observed, converting to temperature. The thermographic study allows a surface observation of the thermal effects in order to display the result as a film of the temperature distribution [1]. The present study focuses on the detection of volumetric energy sources in beams covered by viscoelastic patches.