Search results for "Pathologic"

showing 10 items of 710 documents

A virtual reality system for the treatment of stress-related disorders: A preliminary analysis of efficacy compared to a standard cognitive behaviora…

2011

This paper presents preliminary efficacy data in a controlled study of the use of a virtual reality (VR) system for treating stress-related disorders (Post-Traumatic Stress Disorder, or PTSD; Pathological Grief, or PG; and Adjustment Disorders, or AD). ''EMMA's World'' is a VR application in which patients can explore negative experiences to the degree required for their specific therapeutic needs. To accomplish therapeutic goals, a series of virtual elements is customized to be meaningful to the user; the elements contain the fundamental emotional components that the person must confront. Thirty-nine participants diagnosed with PTSD (N=10), PG (N=16), and AD (N=13) were randomly assigned t…

media_common.quotation_subjectAdjustment disordersHuman Factors and ErgonomicsVirtual realityVirtual realityEducationmedicineAdjustment DisorderDepression (differential diagnoses)media_commonStress-related disordersPsychological treatmentsRelaxation (psychology)Post-Traumatic Stress DisorderGeneral EngineeringStress-related disordersCognitionmedicine.diseasePathological GriefHuman-Computer InteractionHardware and ArchitectureAnxietyGriefmedicine.symptomPsychologySoftwareClinical psychologyInternational Journal of Human-Computer Studies
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Depersonalisation, soziale Ängste und Scham

2006

Associations between depersonalization (DP) and social phobia (SP) were described in the early scientific literature. This connection, however, has not yet been considered in the recent empirical literature and clinical trials on SP. The aim of this study is to examine these associations. In a sample of 100 consecutive inpatients we compare 45 patients with pathological DP to 55 patients without pathological DP with respect to comorbidity and the degree of social anxieties assessed with the SOCIAL INTERACTION ANXIETY SCALE (SIAS) and with the SOCIAL PHOBIA SCALE (SPS) and the extent of shame assessed with the INTERNALIZED SHAME SCALE (ISS). Social phobia was significantly more prevalent in …

media_common.quotation_subjectSocial anxietyShamemedicine.diseaseComorbiditySocial relationPsychiatry and Mental healthClinical PsychologyDepersonalizationmedicinemedicine.symptomLiterature studyPsychologyPathologicalApplied PsychologyAnxiety scalemedia_commonClinical psychologyPPmP - Psychotherapie · Psychosomatik · Medizinische Psychologie
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MRI of inner ear fluids using modified GRASS sequences: a useful tool in the assessment of the normal and pathological labyrinth

1995

MRI is acquiring a progressively more important role in the investigation of petrous bone disease. Nevertheless, despite the extensive use of MRI in the detection of inflammatory or neoplastic involvement of the seventh and eighth cranial nerves, conventional spinecho images cannot be considered the modality of choice in inner ear imaging “Steady-state sequences” are known to be motion sensitive. By setting a very short repetition time, a large flip angle and a long echo time, one can obtain a sequence sufficiently sensitive to the slow movement of endo- and perilymph. We report our experience in MRI of normal and pathological inner ear with modified GRASS sequences.

medicine.diagnostic_testEcho timeCranial nervesMagnetic resonance imagingAnatomyBiologyPerilymphmedicine.anatomical_structureRepetition TimeFlip angleotorhinolaryngologic diseasesmedicineInner earsense organsPathological
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Remodeling of Cortical Structural Networks in Multiple Sclerosis

2019

Multiple sclerosis (MS) is one of the most frequent immune-mediated disorders of the central nervous system. Pathological events occurring within the white matter and gray matter compartments can be reliably tracked in vivo by magnetic resonance imaging (MRI) but conventional imaging parameters do not reflect the remodeling processes of the brain. Here, we sought to investigate the reorganization of cortical structural networks in a group of patients with MS. For this, 40 patients (mean age ± standard deviation 31.2 ± 7.0 years, 14 males) with relapsing-remitting MS and 40 healthy subjects (27.1 ± 5.0 years, 14 males) were included in the study. From T1-weighted MR image-derived cortical th…

medicine.diagnostic_testbusiness.industryMultiple sclerosisCentral nervous systemMagnetic resonance imagingMean agemedicine.diseaseWhite mattermedicine.anatomical_structuremedicineIn patientbusinessGlobal efficiencyNeurosciencePathological
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Metástasis óseas secundarias a carcinoma renal diagnosticadas mediante gammagrafía ósea

2001

We reported the case of a 35-y-old man with renal cell carcinoma and cold lesions detected by bone scintigraphy, related to metastatic involvement. Conventional X-Ray did not show any pathological findings, being confirmed by axial computed tomography (CT) the scintigraphic bone lesions. We have accomplished a discussion of the role of bone scintigraphy and complementary techniques (radiography, alkaline phosphatase levels) in the diagnosis of bone metastases in renal cell carcinoma.

medicine.diagnostic_testbusiness.industryUrologyRadiographyComputed tomographymedicine.diseaseBone scintigraphyRenal cell carcinomaBone lesionCarcinomaMedicineAlkaline phosphatasebusinessNuclear medicinePathologicalActas Urológicas Españolas
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ANMCO/ELAS/SIBioC Consensus Document: Biomarkers in heart failure

2017

Abstract Biomarkers have dramatically impacted the way heart failure (HF) patients are evaluated and managed. A biomarker is a characteristic that is objectively measured and evaluated as an indicator of normal biological or pathogenic processes, or pharmacological responses to a therapeutic intervention. Natriuretic peptides [B-type natriuretic peptide (BNP) and N-terminal proBNP] are the gold standard biomarkers in determining the diagnosis and prognosis of HF, and a natriuretic peptide-guided HF management looks promising. In the last few years, an array of additional biomarkers has emerged, each reflecting different pathophysiological processes in the development and progression of HF: …

medicine.drug_classFibrosiGalectin 3Heart failure030204 cardiovascular system & hematologyBioinformatics03 medical and health sciences0302 clinical medicineFibrosismedicineNatriuretic peptideNatriuretic peptides030212 general & internal medicineBiomarkers; Fibrosis; Galectin 3; Heart failure; Inflammation; Natriuretic peptides; Troponin; Cardiology and Cardiovascular MedicinePathologicalInflammationbiologybusiness.industryArticlesBiomarkermedicine.diseaseBrain natriuretic peptideFibrosisTroponinTroponinGalectin-3Heart failurebiology.proteinBiomarker (medicine)businessCardiology and Cardiovascular MedicineBiomarkers; Fibrosis; Galectin 3; Heart failure; Inflammation; Natriuretic peptides; TroponinBiomarkersNatriuretic peptide
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Tumors of the labial mucosa: a retrospective study of 1045 biopsies

2020

Background To investigate the relative frequency of localized mucosal swellings of the upper and lower labial mucosa, the clinical-pathological diagnosis agreement and whether patient’s age and gender and tumor’s site and size may raise the suspicion of neoplasm. Material and Methods Retrospective analysis was performed on upper or lower labial mucosal tumors, histopathologically diagnosed between 2009-2018. The diagnostic categories developmental/reactive tumors, benign and malignant neoplasms were associated with patient’s age and gender and tumor’s site and size; clinical-pathological diagnosis agreement was, also, evaluated. Results Overall, 1000 (95.7%) developmental/reactive tumors, 3…

medicine.medical_specialtyAdenomainflammatory mediatorsBiopsyLower lipelderlyGastroenterologyInternal medicinemedicineNeoplasmHumansLabial MucosaperiodontitisGeneral DentistryPathologicalUNESCO:CIENCIAS MÉDICASRetrospective StudiesOral Medicine and Pathologybusiness.industryResearchneurodegenerationUpper lipMouth MucosaRetrospective cohort studyLipomamedicine.diseaseLipstomatognathic diseasesOtorhinolaryngologyLip Neoplasmsalzheimer´s diseaseSurgerybusinessMedicina Oral, Patología Oral y Cirugía Bucal
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Regenerative Medicine: Does Erythropoietin have a Role?

2009

Regenerative Medicine, a recent new medical domain, aims to develop new therapies through the stimulation of natural regenerative processes also in human beings. In this field, Erythropoietin (EPO) represents a significant subject of research. Several studies allow the assertion that EPO, in different concentrations, has protective effects mainly on the central nervous system, cardiovascular system and renal tissue. This action is carried out through one of few regenerative activities of human beings: angiogenesis. This mechanism, which involves endothelial stem cells and VEGF (Vascular Endothelial Growth Factor), has been experimentally demonstrated with Recombinant human erythropoietin (r…

medicine.medical_specialtyAngiogenesisNeovascularization PhysiologicRegenerative MedicineBioinformaticsModels BiologicalAngiogenesis; Erythropoietin; Regenerative medicineRegenerative medicineNeovascularizationchemistry.chemical_compoundModelsNeoplasmshemic and lymphatic diseasesInternal medicineDrug DiscoverymedicineAnimalsHumansRegenerationPhysiologicErythropoietinZebrafishNeovascularizationPathologicPharmacologyNeovascularization Pathologicbiologybusiness.industryMechanism (biology)FishesAnimals Erythropoietin Fishes Humans Models; Biological Neoplasms Neovascularization; Pathologic Neovascularization; Physiologic Regeneration Regenerative MedicineBiologicalbiology.organism_classificationVascular endothelial growth factorEndothelial stem cellEndocrinologychemistryErythropoietinmedicine.symptombusinessmedicine.drugCurrent Pharmaceutical Design
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Comparison between Two Different Two-Stage Transperineal Approaches to Treat Urethral Strictures or Bladder Neck Contracture Associated with Severe U…

2012

Introduction.The recurrence of urethral/bladder neck stricture after multiple endoscopic procedures is a rare complication that can follow prostatic surgery and its treatment is still controversial.Material and Methods.We retrospectively analyzed our data on 17 patients, operated between September 2001 and January 2010, who presented severe urinary incontinence and urethral/bladder neck stricture after prostatic surgery and failure of at least four conservative endoscopic treatments. Six patients underwent a transperineal urethrovesical anastomosis and 11 patients a combined transperineal suprapubical (endoscopic) urethrovesical anastomosis. After six months the patients that presented comp…

medicine.medical_specialtyArticle SubjectUrethral stricturebusiness.industryUrologyUrethral sphincterBladder neck contractureObstetrics and GynecologyLumen (anatomy)Urinary incontinenceAnastomosislcsh:Diseases of the genitourinary system. Urologylcsh:RC870-923medicine.diseaseSurgeryNeck of urinary bladderClinical StudymedicineProstatectomy | Constriction Pathologic | neck contracturemedicine.symptomComplicationbusinessAdvances in Urology
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Indirekte MR-Arthrographie zur Verlaufskontrolle nach autologer osteochondraler Transplantation

2003

Purpose: To evaluate the spectrum of findings in indirect MR-arthrography following autologous osteochondral transplantation. Patients and Methods: 10 patients with autogenous osteochondral homografts underwent indirect MR-arthrography at three, 6 and 12 months postoperatively. The MR protocol at 1.5 T comprised unenhanced imagings with PD- and T 2 -weighted TSE-sequences with and without fat-suppression as well as T 1 -weighted fat-suppressed SE-sequences before and after iv. contrast ad ministration and after active joint exercise. Image analysis was done by two radiologists in conference and comprised the evaluation of signal intensity (Sl) and integrity of the osseous plug and the carti…

medicine.medical_specialtyBone diseaseHyaline cartilagebusiness.industryCartilageFollow up studiesJoint effusionBone marrow edemamedicine.diseaseSurgerymedicine.anatomical_structuremedicineRadiology Nuclear Medicine and imagingmedicine.symptombusinessPathologicalFixation (histology)RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
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