Search results for "Pathology"

showing 10 items of 8489 documents

Microglia and α-synuclein implication in Parkinson's disease

2011

Age-related neurodegenerative disorders like Parkinson’s disease take an enormous toll on individuals and on society. Despite extensive efforts, Parkinson’s disease remains incurable and only very limited treatments exist. Indeed, Parkinson’s pathogenesis is still not clear and research on its molecular mechanisms is ongoing. In this study, we focused our interest on two abnormal events occurring in Parkinson’s patients, namely α-synuclein aggregation and microglial activation. We first investigated α-synuclein and its abnormal polymerisation. For this purpose, we developed novel methods, which allowed the in vitro production of different types of α-synuclein oligomers. Using highly sensiti…

[SDV.SA]Life Sciences [q-bio]/Agricultural sciencesΑ-synucléineAgingMaladie de ParkinsonDopamineCultures primairesBrain immunityNeuronesVieillissementImmunité du cerveauPotassium channelsNeuroinflammationToxicitéC8-B4 cell line[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyMéthode d’isolation in vitroElectrophysiologieCanaux potassiquesNeurodegeneration[ SDV.SA ] Life Sciences [q-bio]/Agricultural sciencesIn vitro isolation methodPrimary cultureKv1.3 - Kir2.1Neurons[SDV.SA] Life Sciences [q-bio]/Agricultural sciences[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyToxicityMaladies neurodégénérativesΑ-synucleinNitric oxideNeurodégénérationOligomèresElectrophysiologyMicrogliesBrain macrophagesOligomersOxyde nitriqueNeurodegenerative disordersParkinson’s diseaseCytokinesLignée cellulaire C8-B4MicrogliaPatch-clamp[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Gustatory evoked cortical activity in humans in response to saccharose stimuli

2014

[SDV.SP] Life Sciences [q-bio]/Pharmaceutical sciences[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition[SDV.MHEP.PHY] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]saccharosepotentiels évoqués gustatifs[SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]saveur primaire
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Perturbateurs endocriniens. Effets des expositions précoces (femme enceinte). Fertilité – Développement – Cancer. Troubles sensoriels et comportement

2013

[SDV.TOX] Life Sciences [q-bio]/Toxicology[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathology[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutrition[SDV.TOX]Life Sciences [q-bio]/Toxicology[ SDV.TOX ] Life Sciences [q-bio]/Toxicology[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Perturbateurs endocriniens : altérations comportementales et sensorielles

2012

Perturbateurs endocriniens : altérations comportementales et sensorielles. Neurotoxicologie comportemental et toxicologie sensorielle

[SDV.TOX] Life Sciences [q-bio]/Toxicology[SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutrition[SDV.TOX]Life Sciences [q-bio]/Toxicology[ SDV.TOX ] Life Sciences [q-bio]/Toxicology[ SDV.MHEP.EM ] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism[SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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Involvement of plasmalogens and polyunsaturated fatty acids in the pathogenesis of glaucoma

2013

[SDV.TOX] Life Sciences [q-bio]/Toxicologyphospholipideacide gras[SDV.MHEP.OS] Life Sciences [q-bio]/Human health and pathology/Sensory Organs[ SDV.MHEP.OS ] Life Sciences [q-bio]/Human health and pathology/Sensory Organsrétine[SDV.TOX]Life Sciences [q-bio]/Toxicology[ SDV.TOX ] Life Sciences [q-bio]/Toxicologyglaucome[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organslipide
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ALIMADENT : un projet de recherche participatif pour développer des recettes adaptées aux capacités bucco-dentaires des personnes âgées

2022

[SDV] Life Sciences [q-bio]Oral confort[SDV.AEN] Life Sciences [q-bio]/Food and NutritionElderlyOral healthMeat[SDV.MHEP.GEG] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyOlder adultsRecipedental statusAged adultsalivaryTexture
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Former les professionnels à l'alimentation des personnes âgées : revue critique des formations disponibles en France

2022

[SDV] Life Sciences [q-bio][SDV.AEN] Life Sciences [q-bio]/Food and NutritionNutrition and DieteticsHealthcare professional[SDV.MHEP.GEG] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyEndocrinology Diabetes and MetabolismInternal MedicineTrainingFormationOlder adultAged
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Prévalence de la dénutrition chez les personnes âgées dépendantes pour leur alimentation

2022

[SDV] Life Sciences [q-bio][SDV.AEN] Life Sciences [q-bio]/Food and NutritionNutrition and Dietetics[SDV.MHEP.GEG] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyNursing homeEndocrinology Diabetes and MetabolismMalnutritionInternal MedicineUndernutritionOlder adultDependenceAged
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Prévenir la déshydratation tout en contribuant au lien social en EHPAD : impact du chariot GLACE

2023

[SDV] Life Sciences [q-bio][SDV.AEN] Life Sciences [q-bio]/Food and NutritionNutrition and Dietetics[SDV.MHEP.GEG] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyNursing homeEndocrinology Diabetes and MetabolismOlder adultsAged adultsInternal MedicineDeshydratation
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Odorant metabolism in olfactory mucus: characterization and impact on olfactory perception

2018

[SDV] Life Sciences [q-bio][SDV.AEN] Life Sciences [q-bio]/Food and Nutrition[SDV.BA] Life Sciences [q-bio]/Animal biology[SDV.MHEP.PHY] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO][SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO][SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular Biology[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC][SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC][SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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