Search results for "Patients"

What are the benefits of a minimally invasive approach in frail octogenarian patients undergoing aortic valve replacement?

2016

Not available

In vivo manipulation of Vgamma9Vdelta2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients.

2010

The potent anti-tumour activities of gamma delta T cells have prompted the development of protocols in which gamma delta-agonists are administered to cancer patients. Encouraging results from small Phase I trials have fuelled efforts to characterize more clearly the application of this approach to unmet clinical needs such as metastatic carcinoma. To examine this approach in breast cancer, a Phase I trial was conducted in which zoledronate, a V gamma 9V delta 2 T cell agonist, plus low-dose interleukin (IL)-2 were administered to 10 therapeutically terminal, advanced metastatic breast cancer patients. Treatment was well tolerated and promoted the effector maturation of V gamma 9V delta 2 T …

The impact of a history of psychotic symptoms on cognitive function in euthymic bipolar patients: a comparison with schizophrenic patients and health…

2011

BACKGROUND: About two-thirds of patients with bipolar disorder (BD) have a lifetime history of at least one psychotic symptom. Objective: To compare the neurocognitive performance of four groups: BD patients with and without a history of psychotic symptoms (BD HPS+ and BD HPS-, respectively); patients with schizophrenia (SZ); and healthy control (HC) subjects. METHOD: In this cross-sectional study, 35 stabilized patients with SZ, 79 euthymic (44 HPS+ and 35 HPS-) patients with BD, and 50 HC were administered a comprehensive battery of neuropsychological tests. RESULTS: There was worse neurocognitive functioning in both BD and SZ patients compared to HC. Overall, data from both groups of BD …

Twenty-year trends in the prevalence of Down syndrome and other trisomies in Europe : impact of maternal age and prenatal screening

2013

This study examines trends and geographical differences in total and live birth prevalence of trisomies 21, 18 and 13 with regard to increasing maternal age and prenatal diagnosis in Europe. Twenty-one population-based EUROCAT registries covering 6.1 million births between 1990 and 2009 participated. Trisomy cases included live births, fetal deaths from 20 weeks gestational age and terminations of pregnancy for fetal anomaly. We present correction to 20 weeks gestational age (ie, correcting early terminations for the probability of fetal survival to 20 weeks) to allow for artefactual screening-related differences in total prevalence. Poisson regression was used. The proportion of births in …

Granzyme A is an additional marker for tuberculosis (TB) to discriminate between patients with active disease and subjects with latent infection.

2013

An Analysis of “No Effect of Insulin Pen with Memory Function on Glycemic Control in a Patient Cohort with Poorly Controlled Type 1 Diabetes: A Rando…

2012

Missing meal bolus and nonadherence is an important barrier to achieving glycemic goals in type 1 diabetes (T1DM). In this issue of Journal of Diabetes Science and Technology, Danne and coauthors reported the results of a 24-week randomized-controlled study designed to evaluate if using an insulin pen with memory function, the HumaPen® Memoir™, might improve injection compliance and, therefore, overall glycemic control in T1DM. Patients treated with the pen device with memory function improved, albeit nonsignificantly, their mean HbA1c by 0.43%. Among the reasons to justify why this study was not positive, the most important is the high proportion of adult patients included in the study (87…

Communicator styles of hospital patients during nurse-patient counseling.

2002

Abstract This article describes nurse–patient communication during counseling sessions. It focuses on the patient as a participant in a discussion and aims at a description of patients’ communicator styles, which were observed on videotape based on 38 counseling sessions transcribed word by word. Interviews of the participating nurses and patients were used for partial support of the interpretations. The analytic method chosen was typology, and it has been used for achieving a multifaceted qualitative description of patient communication. The research material yielded seven types of communicator styles: Quietly Assenting, Emotionally Expressive, Storyteller, Stoic Observer, Inquisitive of D…

Prevalence of the patients with history of hepatitis in a dental faculty

2006

Objectives: The aim of the study is to investigate the prevalence of the dental patients who had a history of hepatitis. Study design: A total of 13.527 records of patients who were examined between October 1, 2002 and October 1, 2004 were reviewed retrospectively. The medical histories of patients were taken before routine clinical and radiographic examination. A dental software program was used for the collection of data. The chi-square test was utilized to evaluate correlations between different parameters. Results: The percentage of the patients who had a medical history of hepatitis was 7.9% (n=1065). Within the total patients; history of hepatitis A was found as 3.2% (n=438), hepatiti…

Predictors of mortality in COPD patients after hospitalization due to an exacerbation

2019

Aim: Identify factors related to mortality at 6 months after hospitalization by an acute COPD exacerbation (AECOPD). Method: We performed a 12-month prospective, observational study (July 2017-June 2018) that included COPD patients admitted by an AECOPD. Sociodemographic data, comorbidities, functional and clinical parameters were collected. Mortality at 6 months of admission was considered the end point. Results: 278 consecutive patients were enrolled, of whom 48 (16.2%) died during 6 months after AECOPD. Univariate analysis showed that age (p Conclusions: In COPD patients, Barthel Index, grade of dyspnea and previous hospitalizations are independent risk factors for mortality at 6 months,…

Vitamin D and Osteoporosis in HIV/HCV Coinfected Patients: A Literature Review

2015

Vitamin D deficiency further increases the risk of osteoporosis in HIV-positive patients coinfected with hepatitis C virus (HCV); however, it is still unclear whether HCV-related increased fracture risk is a function of the severity of liver disease. The aim of this review was to identify studies on associative vitamin D deficiency patterns in high-risk populations such as HIV/HCV coinfected patients. We did this by searching MEDLINE and EMBASE databases, from inception to August 2014, and included bibliographies. The final 12 articles selected are homogeneous in terms of age but heterogeneous in terms of sample size, participant recruitment, and data source. Most of the HIV/HCV coinfected …