Search results for "Pattern analysis"

showing 10 items of 50 documents

Different Representation Procedures Originated from Multivariate Temporal Pattern Analysis of the Behavioral Response to Pain in Wistar Rats Tested i…

2019

Temporal pattern analysis is an advanced multivariate technique able to investigate the structure of behavior by unveiling the existence of statistically significant constraints among the interval length separating events in sequence. If on the one hand, such an approach allows investigating the behavioral response to pain in its most intimate and inner features, on the other hand, due to the meaning of the studies on pain, it is of relevant importance that the results utilize intuitive and easily comprehensible ways of representation. The aim of this paper is to show various procedures useful to represent the results originating from the multivariate T-pattern analysis of the behavioral re…

Multivariate statisticsMultivariate analysisPain -- Animal modelsPattern analysisNeurophysiologyT-pattern analysisSettore BIO/09 - FisiologiaArticlemultivariate analyseslcsh:RC321-571medicinepainHot platelcsh:Neurosciences. Biological psychiatry. NeuropsychiatryAnimal behavior -- Statistical methodsmultivariate analyseMorphineGeneral NeuroscienceRepresentation (systemics)T-pattern analysimorphinehot-plateBehavioral responseMultivariate analysisMorphineT-patternPsychologyNeurosciencemedicine.drug
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Brain histamine and oleoylethanolamide restore behavioral deficits induced by chronic social defeat stress in mice.

2021

The physiological mechanisms underlying the complex interplay between life stressors and metabolic factors is receiving growing interest and is being analyzed as one of the many factors contributing to depressive illness. The brain histaminergic system modulates neuronal activity extensively and we demonstrated that its integrity is necessary for peripheral signals such as the bioactive lipid mediator oleoylethanolamide (OEA) to exert its central actions. Here, we investigated the role of brain histamine and its interaction with OEA in response to chronic social defeat stress (CSDS), a preclinical protocol widely used to study physio-pathological mechanisms underlying symptoms observed in d…

Neurophysiology and neuropsychologyPhysiologyHistidine decarboxylaseNeurosciences. Biological psychiatry. NeuropsychiatryT-pattern analysis OxytocinT-pattern analysisOxytocinSettore BIO/09 - FisiologiaBiochemistrySocial interactionSocial defeatRecognition memory03 medical and health sciencesCellular and Molecular Neurosciencechemistry.chemical_compoundOleoylethanolamide0302 clinical medicineEndocrinologyMedicineChronic stressOriginal Research ArticleNeurotransmitterRC346-429Molecular BiologySocial stressEndocrine and Autonomic Systemsbusiness.industryHistidine decarboxylase; Oxytocin; Recognition memory; Social interaction; T-pattern analysisQP351-495HistaminergicHistidine decarboxylase030227 psychiatrychemistryNeurology. Diseases of the nervous systembusinessNeuroscience030217 neurology & neurosurgeryHistamineRC321-571Neurobiology of stress
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Structural Analyses in the Study of Anxiety and Anxiety-Related Behaviour

2016

According to the latest Diagnostic and Statistical Manual of Mental Disorders, 5th edition, anxiety encompasses various conditions sharing an excessive sense of fear and/or apprehension for no evident reason and related behavioural disturbances (Association, 2013). The association of such a gloomy symptomatology, with the great diffusion in the general population, explains the critical impact of anxiety disorders on inter-personal relationships and job-related activities (Greenberg et al.,1999; Wittchen & Hoyer, 2001; Keeley & Storch, 2009). Hence, anxiety disorders represent an important and consistent topic of discussion, not only in terms of underlying neuro-psychological processes but, …

NeurosciencesAnxietyMultivariate analysis cluster analysis stochastic analysis adjusted residuals T-pattern analysis ratSettore BIO/09 - Fisiologia
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Photoelastic stress pattern analysis using Fourier transform with carrier fringes: influence of quarter-wave plate error

2002

The Fourier transform method, widely applied in photomechanics for the automated analysis of interferometric fringe patterns, has been recently extended to the photoelastic isochromatic fringe patterns analysis. Unfortunately, its use in photoelasticity involves some limitations that have not been completely highlighted in literature. This work deals with the influence of the quarter-wave plate tolerance on the evaluation of the retardation. Both theoretical and experimental analyses have shown that the quarter-wave plate error does not affect the retardation only if the principal stress directions in the model and in the carrier are aligned. In general, instead, the tolerance of the quarte…

PhotoelasticityMaterials scienceField (physics)business.industryMechanical EngineeringPattern analysisWaveplateAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic MaterialsStress (mechanics)Interferometrysymbols.namesakeOpticsFourier transformsymbolsPrincipal stressElectrical and Electronic EngineeringbusinessOptics and Lasers in Engineering
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Brain histamine depletion enhances motor sequences complexity of mice tested in open field: new insights from temporal pattern analysis

2016

Background: Tourette Syndrome (TS) has been classically related to dopaminergic dysregulation of Basal Ganglia circuitry [1]. However, the identification of a rare autosomal dominant form of TS, linked to a mutation of the key-enzyme for Histamine (HA)1 synthesis (l-Histidine decarboxylase, Hdc), has shed light on a putative involvement of this monoamine on the pathophysiology of tic and related disorders and fostered the development of coherent animal models [2]. Although HA-deficient rodents display markedly increased tic-like stereotypies following amphetamine administration, neither underlying nor predisposing differences in the open field test have been reported in quantitative measure…

Settore BIO/09 - FisiologiaHistamine T-pattern analysis mice
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T-Pattern analysis of rodent behavioral response to anxiety in hole-board

2009

Settore BIO/09 - FisiologiaT-pattern analysis hole-board multivariate analysis anxiety rat
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Metilazione del DNA in artrite reumatoide

2005

Lo stato di metilazione del DNA genomico e del gene PTHrP è stato valutato con tecniche molecolari e citogenetiche in artrite reumatoide (AR), patologia autoimmune caratterizzata anche da alta incidenza di linfomi e da ipercalcemia per overespressione del gene PTHrP. La metilazione del DNA, infatti, ha un ruolo critico nello sviluppo delle malattie neoplastiche; il gene PTHrP avendo tre promotori uno dei quali contiene un’isola CpG è un buon candidato per la deregolazione da alterato pattern di metilazione locale. Le indagini sulla metilazione genomica, condotte su DNA estratto da sangue periferico di pazienti e di donatori e amplificato in reazioni di Methylation-Sensitive Arbitrarily Prim…

Settore BIO/18 - Geneticainstead chromosomes of controls were almost uniformly decorated by brilliant grains. Studies on methylation of PTHrP gene promoter 2 performed on five CpG island internal sites using the Methylation-Sensitive Restriction Endonuclease Multiplex (MSREM)-PCR showed that one of the sites nearest the trascription starting point is heavy methylated in a significantly high number of RA patients. Thus RA seems to be characterized by genomewide hypomethylation associated with local hypermethylation like the most part of tumors. This result raises the possibility that susceptibility to lymphomas is related to abnormal DNA methylation levels and suggests the opportunity to evaluate the DNA methylation status in RA patientin fact the demethylating therapies together with diet and life style can act towards an increase of tumor risk. Future studies using a larger number of subjects could confirm these findings.Rheumatoid Arthritis (RA) is a chronic multisystem inflammatory disease characterized by high recurrence of lymphomas as well as hypercalcemia due to PTHrP overexpression. Because of DNA methylation plays a critical role in development of neoplasias we determined in RA patients the global DNA methylation status and local methylation pattern of the CpG island of one of the three promoters of PTHrP gene utilizing molecular and cytogenetic techniques. Investigations performed on DNA from peripheral blood of patients and donors amplified by Methylation-Sensitive Arbitrarily Primed (MeS-AP)-PCR indicated that RA is strongly associated with global DNA hypomethylation. Similarly chromosomal DNA methylation pattern analysis by indirect immunofluorescence technique with anti 5-methylcitosine antibody showed all peripheral lymphocyte metaphases from RA patients with chromosomes weakly fluorescent without discrete grain
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Likelihood Inference for Gibbs Processes in the Analysis of Spatial Point Patterns

2001

Plusieurs auteurs ont propose des approximations stochastiques et non-stochastiques au MLE pour les processus de Gibbs utilises pour decrire les interactions entre deux points dans une distribution spatiale de points. Cettes approximations sont necessaires a cause de la difficulte en l'evaluation de la constante qui normalise la f.d.p., Cet article present une comparaison, parmi d'un model de Strauss, des methodes qui utilisent des approximations directes aux MLE et des methodes qui utilisent techniques de Monte Carlo de chaine de Markov. Les techniques de simulation utilisees sont le Gibbs sampler et l'algorithm de Metropolis-Hastings.

Statistics and ProbabilitySequential methodMaximum likelihoodCalculusPattern analysisApplied mathematicsInferenceStatistics Probability and UncertaintyMathematicsInternational Statistical Review
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Discovering Hidden Temporal Patterns in Behavior and Interaction

2016

Discovering hidden recurring patterns in observable behavioral processes is an important issue frequently faced by numerous advanced students and researchers across many research areas, such as, for example, psychology, biology, sports, robotics, media, fi nance, and medicine. As generally, the many powerful methods included in statistical software packages were not developed for this kind of analysis, discovering such patterns has proven a particularly diffi cult task, due to a lack of (a) adequate formalized models of the kinds of patterns to look for, (b) corresponding detection algorithms, and (c) their implementation in available software. The research described in this book is based o…

T-pattern analysis
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INTRODUCTION

2016

Discovering hidden recurring patterns in observable behavioral processes is an important issue frequently faced by numerous advanced students and researchers across many research areas, such as, for example, psychology, biology, sports, robotics, media, finance, and medicine. As generally, the many powerful methods included in statistical software packages were not developed for this kind of analysis, discovering such patterns has proven a particularly difficult task, due to a lack of (a) adequate formalized models of the kinds of patterns to look for, (b) corresponding detection algorithms, and (c) their implementation in available software. The research described in this book is based on …

T-pattern analysis TPA
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