Search results for "Paz"
showing 10 items of 1302 documents
Large deflection analysis of magneto-electro-elastic laminates
2013
Magneto-electro-elastic (MEE) composites containing piezoelectric and piezo-magnetic phases have recently emerged for many application smart structures technology. In this framework, the development of tools to analyze the MEE laminates is essential for their efficient design. In the present work, a model for the large deflection analysis of MEE laminated plates is proposed. The first order shear deformation theory and the von Karman stress function approach are employed to model the mechanical behavior whereas quasi-static behavior is assumed for the electro-magnetic quantities. First, the magneto-electric problem is solved in terms of the plate mechanical primary variables. In turn, this …
Dynamic analysis of damaged magnetoelectroelastic laminated structures
2010
In the present paper a boundary element analysis of the dynamic response of damaged magnetoelectroelastic laminate structures is presented. The problem is formulated employing generalized displacements. The mass matrix is computed by the Dual Reciprocity Method. Due to the non-homogeneous nature of the laminate the multidomain boundary element technique is employed which also straightforwardly allows the modeling of interface cracks and delaminations. The multidomain boundary element technique is implemented with imperfect interlaminar interfaces and unilateral interface conditions to prevent the physical inconsistence of the overlapping between interface nodes belonging to two different pl…
Osteonecrosis of the jaw (ONJ) in renal cell cancer patients after treatment including zoledronic acid or denosumab.
2014
Dear Editor, The paper by Henry et al. published by Supportive Care in Cancer comparing efficacy of denosumab versus zoledronic acid in patients with bone metastases of advanced solid tumours [1] comes to integrate the original reports of three pivotal large randomized phase 3 trials [2–4], the publication by Saad et al. about osteonecrosis of the jaw (ONJ) in those three trials [5], and the combined outcome analysis by Lipton et al. [6]. Henry et al. [1] reported outcomes of the single trial conducted on patients with solid tumours (except breast or prostate cancers, object of other two trials) [2, 3], excluding patients with multiple myeloma: This ad hoc analysis confirmed the superiority…
Regulation of noradrenergic coerulean neuronal firing mediated by 5-HT2 receptors: involvement of the prepositus hypoglossal nucleus.
1991
Abstract Previous studies have indicated a 5-HT2-mediated inhibitory influence on unit activity in the locus coeruleus. In the present work, attempts were made to determine which area(s) of the brain is (are) involved in this effect: (1) Microiontophoretic application of serotoninergic compounds (quipazine, ketanserin, RU 24969 (Roussel Uclaf), 8-hydroxy-2(di-n-propylamino) tetralin (8-OH-DPAT), metergoline, serotonin) in the locus coeruleus, did not alter the coerulean discharge. Local microinjection of quipazine or ketanserin in the area of the locus coeruleus, as well as in one of its major afferents, the prepositus hypoglossi, had no effect on the unit activity in the locus coeruleus. 1…
Clinical features and lifestyle of patients with amyotrophic lateral sclerosis in Campania: brief overview of an Italian database
2012
Background. Physical activity and occupational exposures appeared to play a relevant role in pathogenesis of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease of unknown origin. Materials and methods. We aimed to make an overview of the clinical characteristics and life - style (occupation and sport) of a population of 395 patients with ALS from campania, in southern Italy. Results. ALS onset resulted anticipated of about 11 years in industry workers, whilst the more frequent site of onset among farmers was upper limbs. compared to non-athletes, athletes, particu- larly soccer players, showed a 7 years anticipation of ALS onset, with higher mortality after 5 years. Discussion…
Urbanus Papa VIII. Ad perpetuam rei memoriam ... Aliàs siquidem pro parte ... Ferdinandi Etruriae ... nobis expositum quod bona memoria ... Maria Ma…
1627
Tres esc. en la parte superior del f.
Elucidating the Effect of Bimodal Grain Size Distribution on Plasticity and Fracture Behavior of Polycrystalline Materials
2020
The refinement of grains in a polycrystalline material leads to an increase in strength but as a counterpart to a decrease in elongation to fracture. Different routes are proposed in the literature to try to overpass this strength-ductility dilemma, based on the combination of grains with highly contrasted sizes. In the simplest concept, coarse grains are used to provide relaxation locations for the highly stressed fine grains. In this work, a model bimodal polycrystalline system with a single coarse grain embedded in a matrix of fine grains is considered. Numerical full-field micro-mechanical analyses are performed to characterize the impact of this coarse grain on the stress-strain const…
A three-dimensional cohesive-frictional grain-boundary micromechanical model for intergranular degradation and failure in polycrystalline materials
2013
Abstract In this study, a novel three-dimensional micro-mechanical crystal-level model for the analysis of intergranular degradation and failure in polycrystalline materials is presented. The polycrystalline microstructures are generated as Voronoi tessellations, that are able to retain the main statistical features of polycrystalline aggregates. The formulation is based on a grain-boundary integral representation of the elastic problem for the aggregate crystals, that are modeled as three-dimensional anisotropic elastic domains with random orientation in the three-dimensional space. The boundary integral representation involves only intergranular variables, namely interface displacement di…
Nonlocal model for a magneto-electro-elastic nanoplate
2013
A mathematical model based on nonlocal third-order shear deformation plate theory has been developed to evaluate the mechanical and electromagnetic behavior of magneto-electro-elastic nanoplates. Two types of magneto-electro-elastic composites have been considered, all of them combination of Barium Titanate sheets, that represents the piezoelectric phase, and Cobalt Ferrite, that is the piezomagnetic component. Setting magneto-electric boundary conditions on each laminate, it has been possible to extrapolate and to analyze free vibrations frequencies for all considered plates, allowing to do objective assessments on what factors influence laminate modes and, especially, how these vary in th…
An enhanced grain-boundary framework for computational homogenization and micro-cracking simulations of polycrystalline materials
2015
An enhanced three-dimensional (3D) framework for computational homogenization and intergranular cracking of polycrystalline materials is presented. The framework is aimed at reducing the computational cost of polycrystalline micro simulations, with an aim towards effective multiscale modelling. The scheme is based on a recently developed Voronoi cohesive-frictional grain-boundary formulation. A regularization scheme is used to avoid excessive mesh refinements often induced by the presence of small edges and surfaces in mathematically exact 3D Voronoi morphologies. For homogenization purposes, periodic boundary conditions are enforced on non-prismatic periodic micro representative volume ele…