Search results for "Pb"
showing 10 items of 3522 documents
Azimuthally Differential Pion Femtoscopy in Pb-Pb Collisions at √sNN = 2.76 TeV
2017
We present the first azimuthally differential measurements of the pion source size relative to the second harmonic event plane in Pb-Pb collisions at a center-of-mass energy per nucleon-nucleon pair of √ s N N = 2.76 TeV . The measurements have been performed in the centrality range 0%–50% and for pion pair transverse momenta 0.2 < k T < 0.7 GeV / c . We find that the R side and R out radii, which characterize the pion source size in the directions perpendicular and parallel to the pion transverse momentum, oscillate out of phase, similar to what was observed at the Relativistic Heavy Ion Collider. The final-state source eccentricity, estimated via R side oscillations, is found to b…
Selective targeting of collagen IV in the cancer cell microenvironment reduces tumor burden
2018
Goodpasture antigen-binding protein (GPBP) is an exportable1 Ser/Thr kinase that induces collagen IV expansion and has been associated with chemoresistance following epithelial-to-mesenchymal transition (EMT). Here we demonstrate that cancer EMT phenotypes secrete GPBP (mesenchymal GPBP) which displays a predominant multimeric oligomerization and directs the formation of previously unrecognized mesh collagen IV networks (mesenchymal collagen IV). Yeast two-hybrid (YTH) system was used to identify a 260SHCIE264 motif critical for multimeric GPBP assembly which then facilitated design of a series of potential peptidomimetics. The compound 3-[4''-methoxy-3,2'-dimethyl-(1,1';4',1'')terphenyl-2'…
A low-level spectrometer with a planar low-energy HPGe: shielding arrangement tests and system performance for 210Pb determination in air filter samp…
2001
A system for low-energy photon spectrometry using a planar germanium detector with appropriate specifications is presented. A spectrometric background investigation has been carried out with various detector shielding arrangements. The characteristics of the system for measurements of 210Pb in air-particulate matter on filters have been determined.
Adaptive and Creative Problem-Projects in the Teaching of Science. Description of the Methodology and Appreciation of the Students Involved
2019
En este artículo se describe la metodología que se ha denominado Aprendizaje Basadoen Problemas-Proyectos Adaptativos y Creativos (ABPac), utilizando como ejemplo algunos de losproyectos realizados en el centro concertado Jesús-María de Burgos durante diez años, entre 2006y 2016, con alumnos de Secundaria Obligatoria y Bachillerato. Esta metodología sugiere una aten-ción a la diversidad del alumnado considerando sus necesidades e inquietudes. Además, se analizacuantitativamente el resultado de la encuesta de percepción realizada a 73 individuos involucradosen esta metodología cuando ya ha transcurrido un tiempo de madurez y se encuentran finalizandosus carreras o con estas ya finalizadas. L…
Granica jako kategoria i paradygmat wychowania
2023
When intentions turn into action: pathways to successful firm performance
2021
Entrepreneurship brings wealth to nations and contributes to their economic growth. People can take many paths to become entrepreneurs. Some join the family business, whilst others are born entrepreneurs, letting their innate intuition lead them into firm creation. For many, though, being able to learn and acquire the right skills is critical for a successful career as an entrepreneur. Like other human capital factors, entrepreneurial skills can be acquired. In today’s fast-changing society, it is of utmost importance for entrepreneurs not only to gain these skills but also to be surrounded by a supportive environment that will (1) guide them in the creation of their business idea and (2) h…
Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis
2018
Abstract: Chemotherapy is currently the only effective approach to treat all forms of leishmaniasis. However, its effectiveness is severely limited due to high toxicity, long treatment length, drug resistance, or inadequate mode of administration. As a consequence, there is a need to identify new molecular scaffolds and targets as potential therapeutics for the treatment of this disease. We report a small series of 1,2‐substituted‐1H‐benzo[d]imidazole derivatives (9ad) showing affinity in the submicromolar range (Ki = 0.150.69 μM) toward Leishmania mexicanaCPB2.8ΔCTE, one of the more promising targets for antileishmanial drug design. The compounds confirmed activity in vitro against intrace…
Applying Artificial Intelligence Methods to Detect and Classify Fish Calls from the Northern Gulf of Mexico
2021
Passive acoustic monitoring is a method that is commonly used to collect long-term data on soniferous animal presence and abundance. However, these large datasets require substantial effort for manual analysis
Measurement of jet suppression in central Pb–Pb collisions at √sNN = 2.76 TeV
2015
The transverse momentum (pT) spectrum and nuclear modification factor (RAA) of reconstructed jets in 0–10% and 10–30% central Pb–Pb collisions at √sNN = 2.76 TeV were measured. Jets were reconstructed using the anti-kT jet algorithm with a resolution parameter of R = 0.2 from charged and neutral particles, utilizing the ALICE tracking detectors and Electromagnetic Calorimeter (EMCal). The jet pT spectra are reported in the pseudorapidity interval of |ηjet| 5 GeV/c to suppress jets constructed from the combinatorial background in Pb–Pb collisions. The leading charged particle requirement applied to jet spectra both in pp and Pb– Pb collisions had a negligible effect on the RAA. The nuclear m…