Search results for "Pediatrics"
showing 10 items of 3912 documents
Plasma cytokine profiles in patients with celiac disease and selective IgA deficiency
2003
Celiac disease (CD) and selective IgA deficiency (IgAD) are frequently associated, and share the same genetic background. The aim of the present study was to evaluate both Type 1 and 2 plasma cytokine levels in CD and in CD-IgAD. IL-2, TNF-alpha, IL-10, IL-4 and IL-13 plasma levels were measured both at diagnosis and after a gluten-free diet (GFD) in 32 CD patients, in 27 CD-IgAD patients and in 30 healthy controls. IFN-gamma levels were significantly higher in CD and CD-IgAD than in controls, TNF-alpha displayed significantly higher levels in CD-IgAD when compared both with controls and with CD, and IL-2 was in CD-IgAD significantly increased respect to controls. Kinetics of the Type 1 cyt…
Externalizing Behaviors and Cigarette Smoking as Predictors for Use of Illicit Drugs: A Longitudinal Study Among Finnish Adolescent Twins
2010
We examined whether externalizing problem behaviors (hyperactivity–impulsivity, aggressiveness, and inattention) predict illicit drug use independently, or whether their associations with drug use are mediated through cigarette smoking. We used a prospective longitudinal design within theFinnTwin12-17study among Finnish adolescents with baseline at age 12 and follow-up surveys at ages 14 and 17. Path models were conducted withMplusand included 1992 boys and 2123 girls. The outcome was self-reported ever use of cannabis or other illicit drugs at age 17. The predictors were: externalizing behaviors (hyperactivity–impulsivity, aggressiveness, and inattention) assessed by teachers and parents (…
Milk Protein Quality in Low Birth Weight Infants
1992
Growth rates tweight, length, and head circumference) and selected biochemical indexes of protein metabolism (serum urea, acid-base status, and plasma amino acid concentrations) were determined in low birth weight (LBW) infants appropriate for gestational age (birth weight < 1,650 g) fed three formu
TAURINE SUPPLEMENTATION PREVENTS HYPERAMINOACIDEMIA IN GROWING TERM INFANTS FED HIGH PROTEIN COW'S MILK FORMULA. † 1891
1996
Blood urea nitrogen (BUN) and plasma and urine amino acid concentrations were compared between three cohorts of healthy term infants who were breast-fed (BF) or randomly assigned to one of two formulas either taurine non-supplemented (FF) or taurine supplemented (FF+T). The formulas had a protein concentration of 2 g/dl (2.9 g/100 kcal) and a whey/casein ratio of 20/80. The infants were studied from 2 to 12 weeks of age. Weight gain and growth in length was normal and similar in all three feeding groups during the study interval. At 12 weeks BUN was significantly higher in the FF group than in the BF and FF+T groups of infants, 16.5 mg/dl vs 7.0 and 7.3 mg/dl respectively. Total plasma amin…
Evidence of the Gluten-Free and Casein-Free Diet in Autism Spectrum Disorders
2014
In autism spectrum disorders, many parents resort to alternative treatments and these are generally perceived as risk free. Among these, the most commonly used is the gluten-free, casein-free diet. The objective of this work was to conduct a systematic review of studies published from 1970 to date related to the gluten-free, casein-free diet in autism spectrum disorder patients. Few studies can be regarded as providing sound scientific evidence since they were blinded randomized controlled trials, and even these were based on small sample sizes, reducing their validity. We observed that the evidence on this topic is currently limited and weak. We recommend that it should be only used after…
Adult Lactose Tolerance Is Not an Advantageous Evolutionary Trait
2004
To the Editor. I read with great interest the recent article from Fomon1 in which he refers to the well-known hypothesis that views the variable frequencies of lactase persistence in different human populations and, consequently, the possibility for some adults to feed on milk (lactose tolerance) as an advantageous evolutionary trait that has been genetically determined and brought about through centuries of natural selection. This notion stands as a common statement in current medical literature, and most authors have accepted its validity since the 1970s.2,3 Because adult mammals are lactose-intolerant, this hypothesis is, moreover, based on the low percentage of lactose malabsorption and…
The systemic immune-inflammation index and neutrophil-lymphocyte ratio in pediatric burned patients – a pilot study
2023
Introduction: The aim was to assess the usefulness of blood analytical markers such as systemic immuneinflammation index (SII) and neutrophil-lymphocyte ratio (NLR) in pediatric burned patients. Material and methods: The study group included 73 children (23 girls and 50 boys; mean age: 3.83; SD: 4.77; min–max: 0–17 years old) hospitalized due to burns. A retrospective analysis of selected complete blood cell count parameters (leucocytes; platelets – PLT; SII; NLR) collected on the day of injury and selected parameters of burns (extent, depth of the injury, duration of hospitalization, type of treatment) was performed. Results: Children with burns that exceeded 10% total body surface area ha…
Prospective analysis of the influence of sport and educational factors on the prevalence and initiation of smoking in older adolescents from Croatia
2017
The prevalence of smoking among Croatian adolescents is alarmingly high, but no previous study has prospectively examined the sport- and academic-factors associated with smoking and smoking initiation. This study aimed to prospectively examine the associations between scholastic (educational) achievement and sport factors and smoking in 16- to 18-year-old adolescents. This two-year prospective cohort study included 644 adolescents who were 16 years of age at baseline (46% females). Baseline testing was implemented at the beginning of the 3rd year of high school (September 2014) when participants were 16 years old. Follow-up testing was completed at the end of the fourth year of high school,…
Exercise as therapy for neurodevelopmental and cognitive dysfunction in people with a Fontan circulation: A narrative review
2023
People with a Fontan circulation are at risk of neurodevelopmental delay and disability, and cognitive dysfunction, that has significant implications for academic and occupational attainment, psychosocial functioning, and overall quality of life. Interventions for improving these outcomes are lacking. This review article discusses current intervention practices and explores the evidence supporting exercise as a potential intervention for improving cognitive functioning in people living with a Fontan circulation. Proposed pathophysiological mechanisms underpinning these associations are discussed in the context of Fontan physiology and avenues for future research are recommended.
Children’s Right to Play and Its Implementation: A Comparative, International Perspective
2021
The child's right to play is specifically addressed in the framework of the Convention on the Rights of the Child. The international recognition of this right is the central theme of this study. Through a documentary analysis of the reports of the States Parties to the Convention and the Concluding Observations of the Committee on the Rights of the Child, the study assesses the recognition of this right. The entry into force of General Comment 17 on the right of the child to rest, recreation, play, recreational activities, cultural life and the arts (art. 31) in 2013 should have marked a turning point in policies on children in the States Parties, but this did not occur. Policies cannot be …