Search results for "Pediatrics"

PS-078 Clinical Relevance Of Gamma-glutamyl Transpeptidase In Childhood Obesity

2014

Background and aims Metabolic risk leads to severe comorbidities in obesity. We evaluate the relationship between the values of gamma-glutamyl trans peptidase (GGT), a marker of hepatic involvement, and cardio metabolic risk factors in obese children. Methods A prospective cross-sectional study of 147 children (aged 7 to 16 years) was carried out. Ninety-five children were obese with a body mass index standard deviation score (SDS-BMI) >2 and 52 children were normal weight. Patients with endocrine disease or syndromic obesity were excluded. We have analysed clinical parameters of adiposity (fat mass by bioelectrical impedance, waist and hip circumference), blood pressure, and classical bioc…

Association of Birth Weight with Central and Peripheral Corneal Thickness in Adulthood-Results from the Population-Based German Gutenberg Health Stud…

2021

Low birth weight (BW) is associated with altered ocular geometry such as a steeper corneal shape in adulthood. However, it is unclear whether low birth weight affects corneal thickness development in the center or periphery in adulthood which may contribute to ocular disease. The purpose of this study was to investigate corneal thickness in former low birth weight individuals in adulthood. Methods: The German Gutenberg Health Study is a prospective, population-based study in which every participant (age range 40–80 years) was measured with Scheimpflug imaging (Pentacam HR, Oculus Optikgeräte GmbH, Wetzlar, Germany). BW was collected by self-reports. The relationship between birth weight and…

PROMOTION OF INTRATHYMIC T-CELL DEVELOPMENT BY MHC-Ia-POSITIVE THYMIC MACROPHAGES (Ia + Mø)

1985

The generation of the peripheral T-cell pool is attributed to maturation and differentiation events occurring within the thymus. Three thymic compartments, thymic epithelial cells, thymic hormons and thymic Mo are considered to contribute to the intrathymic T-cell development. While, as we have shown earlier, murine as well as human MHC-Ia-negative-Mo (Ia−Mo) regulate thymocyte (TH) differentiation via suppressive effects (Thymus,6:295,1984) and MHC-Ia+-Mo are involved in intrathymic tolerance induction (Pediatr Res,15:800, 1984), now the contribution of Ia+Mo to intrathymic lymphopoiesis was investigated. An isolation method yielding cell suspensions highly enriched for Ia+ thymic Mo was p…

1539 Length of Hospital Stay in Children with Acute Viral Pneumonia Treated with Corticosteroids, A Retrospective Study

2012

Background Corticosteroids with or without ephedrine may have positive effects in viral pneumonia treatment accelerating the time to resolution of symtpoms but the evidence is not strong enough to make specific recommandations. Objectives Evaluating the hospital length stay of the children with viral pneumonia treated with corticosteroids, single or in combination with ephedrine. Material and Methods The retrospective study included pacients admitted in our clinic with viral pneumonia during 2011. From 167 cases, 78 cases were selected according to specific criteria: patients having received cortisone (hydrocortisone hemisuccinate and/or fluticasone propionate) associated or not with ephedr…

302 Hearing Abnormalities in Children with Fabry Disease: Data from FOS - the Fabry Outcome Survey

2005

Background: Fabry disease is an X-linked glycosphingolipid storage disorder due to a deficiency of the enzyme alpha-galactosidase A. Accumulation of substrate results in a progressive and life-threatening multisystemic disease. Early clinical manifestations include pain and gastrointestinal symptoms. Sensorineural hearing loss and vertigo are well-recognized features of the disorder, occurring in approximately 50% of adults with Fabry disease. We have investigated the audiological symptoms of Fabry disease in children using pure-tone and impedance audiometry. Methods: Symptom history was obtained using a standardized questionnaire from FOS − the Fabry Outcome Survey. Hearing was measured us…

PO-0779 Which Parameters Are Mandatory In Urinary Tract Infection In Children?

2014

Background The protocol of investigations in urinary tract infection (UTI) in children mandatory includes urianalysis, uroculture, reactive C protein (RCP), blood urea (BUN), renal ultrasonography and scintigraphy. Each one of these has limits to perform in children. Aims To establish the correlations between UTI investigations for argumentation the therapeutic decision. Methods Retrospective study of hospitalised paediatric patients for UTI. The study parameters were: age, symptoms, RCP, BUN, uroculture, renal ultrasonography, urinanalysis (leukocytes, nitrites, pH, density, proteins, erythrocytes, ascorbic acid-AA). Results Were studied 243 hospitalised and treated with antibiotics UTI. U…

Veränderungen in den Skalen Bindung und Steuerung der Achse Struktur der Operationalisierten Psychodynamischen Diagnostik im Kindes- und Jugendalter …

2019

Zusammenfassung. Trotz der hohen Bedeutung, die strukturelle Störungen bei kinder- und jugendpsychiatrischen Patienten haben, fehlen Studien zu deren Veränderung im Verlauf stationärer psychiatrischer Behandlung. Im Rahmen einer Studie zur Wirksamkeit stationärer psychodynamischer Psychotherapie wurden die Dimensionen Steuerung und Bindung der Achse Struktur der Operationalisierten Psychodynamischen Diagnostik im Kindes- und Jugendalter (OPD-KJ) durch das fallführende Tandem (Psychotherapeut und Pädagoge/Pfleger) an 75 Patienten (12–18 Jahre) zu Therapiebeginn und -ende einer 8-wöchigen Behandlung erhoben. Die Zusammenhänge zwischen den Subdimensionen wurden anhand von Interkorrelationen u…

Síndrome de Gianotti-Crosti-like secundario a Molluscum contagiosum

2020

Fatal Late Vitamin K-Deficiency Bleeding After Oral Vitamin K Prophylaxis Secondary to Unrecognized Bile Duct Paucity

1999

2019

Background: Central venous access devices (CVAD) provide important benefits in the management of oncological pediatric patients. However, these catheters are responsible for severe complications. Methods: In this context, we aimed to analyze all patients receiving a CVAD in the Department of Pediatric Hematology and Oncology of the University hospital of Mainz over a period of 9 years, focused on CVAD related complications. Data on demographics, as well as intraoperative and postoperative complications were extracted. Results: A total of 296 patients with a mean age 93.2 ± 62.4 months were analyzed. The majority suffered from leukemia (n = 91, 30.7%), lymphomas (n = 50, 16.9%), and brain tu…