Search results for "People"

showing 10 items of 1330 documents

Long-term health effects on the next generation of Ramadan fasting during pregnancy

2011

Each year, many pregnant women fast from dawn to sunset during the Islamic holy month of Ramadan. Medical theory suggests that this may have negative long-term health effects on their offspring. Building upon the work of Almond and Mazumder (2008), and using Indonesian crosssectional data, I show that people who were exposed to Ramadan fasting during their mother's pregnancy have a poorer general health and are sick more often than people who were not exposed. This effect is especially pronounced among older people, who, when exposed, also report health problems more often that are indicative of coronary heart problems and type 2 diabetes. The exposed are a bit smaller in body size and weig…

AdultMalePediatricsmedicine.medical_specialtyOffspringCross-sectional studyHealth StatusMothersType 2 diabetesBody sizeIslamYoung AdultHealth problemsSDG 3 - Good Health and Well-beingjel:I2PregnancymedicineHumansYoung adultFamily CharacteristicsPregnancybusiness.industryHealth PolicyPublic Health Environmental and Occupational HealthFastingMedical theorymedicine.diseasehealth Ramadan pregnancy nutrition IndonesiaPregnancy Complicationsjel:J1jel:J14Cross-Sectional Studiesjel:I12Socioeconomic FactorsPrenatal Exposure Delayed EffectsIndonesiaPrenatal Exposure Delayed Effects/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleGeneral healthbusinessOlder peopleDemographyhealth; Ramadan; pregnancy; nutrition; Indonesia
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Associations between leprosy and serum protein groups

1970

Serum protein group typings were done on a sample of n=173 adult healthy Negroes from the Macua tribe in Mozambique and on n=129 leprous individuals from the same tribe. Unfortunately, the type of leprosy is not known. Whilst between leprosy and haptoglobins, transferrins and Pi proteins no associations could be observed, statistically significant associations between leprosy and ceruloplasmin resp. β2 I were found. It is pointed out that these associations should be confirmed by further research on other populations and with respect to type and process of leprosy, until biological and population genetical interpretations will be possible.

AdultMalePopulationSerum proteinBlack PeopleTribe (biology)LeprosyGeneticsmedicineHumansAlleleMetabolic diseaseeducationAllelesMozambiqueGenetics (clinical)Glycoproteinseducation.field_of_studyHaptoglobinsbiologyHaptoglobinTransferrinCeruloplasminfood and beveragesmedicine.diseaseBlack or African AmericanGenetics PopulationPhenotypeImmunologyBlood Group Antigensbiology.proteinFemaleLeprosyTrypsin InhibitorsCeruloplasminHuman Genetics
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Self-care appraisal in nursing assistant students: Adaptation, validation and psychometric properties of the Spanish ASAS

2021

The core implication of nursing professionals’ labor is promoting self-care and foster well-being among healthcare service users. The beginning of the healing process starts with the provider, and self-care habits are needed to positively impact on patients’ care outcomes at different spheres. Overall, current literature supports the idea that nurses’ personal self-care should be a necessary skill to be expected in their professional role. In this regard, the Appraisal of Self-care Agency Scale (ASAS) is a worldwide known instrument aimed at assessing the ability to engage in self-care. However, it has never been tested in the Spanish context before, and much less in nursing practitioners o…

AdultMalePsychometricsPatientsScienceHealth Care ProvidersSocial SciencesNursesResearch and Analysis MethodsDiagnostic Self EvaluationNursing ScienceMathematical and Statistical TechniquesNursing AssistantsSurveys and QuestionnairesMedicine and Health SciencesHumansPsychologyTranslationsPublic and Occupational HealthMedical PersonnelStatistical MethodsMultidisciplinarySeguretat viàriaQStatisticsRReproducibility of ResultsBiology and Life SciencesAdaptation PhysiologicalSelf CareHealth CareProfessionsCross-Sectional StudiesHealth Education and AwarenessSpainPeople and PlacesPhysical SciencesMedicineCognitive ScienceFemaleStudents NursingPopulation GroupingsBehavioral and Social Aspects of HealthFactor AnalysisMathematicsResearch ArticleNeuroscience
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A comparison of the cheater detection and the unrelated question models: a randomized response survey on physical and cognitive doping in recreationa…

2016

PURPOSE:This study assessed the prevalence of physical and cognitive doping in recreational triathletes with two different randomized response models, that is, the Cheater Detection Model (CDM) and the Unrelated Question Model (UQM). Since both models have been employed in assessing doping, the major objective of this study was to investigate whether the estimates of these two models converge. MATERIAL AND METHODS:An anonymous questionnaire was distributed to 2,967 athletes at two triathlon events (Frankfurt and Wiesbaden, Germany). Doping behavior was assessed either with the CDM (Frankfurt sample, one Wiesbaden subsample) or the UQM (one Wiesbaden subsample). A generalized likelihood-rati…

AdultMaleQuestionnairesMedical DoctorsPhysiologyHealth Care Providerslcsh:MedicineSurveysResearch and Analysis Methods796 Athletic and outdoor sports and gamesRandom AllocationYoung AdultCognitionGermanySurveys and QuestionnairesPrevalenceMedicine and Health SciencesHumansBiomechanicsSports and Exercise Medicinelcsh:ScienceSwimmingAgedDoping in SportsLikelihood FunctionsBehaviorSurvey Research796 SportBiological Locomotionlcsh:RBiology and Life SciencesMiddle AgedModels TheoreticalSports ScienceBody HeightHealth CareProfessionsPhysiological ParametersResearch DesignPeople and PlacesRecreationCognitive Sciencelcsh:QFemalePopulation GroupingsResearch ArticleSportsNeuroscience
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Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error

2013

Refractive errors are common eye disorders of public health importance worldwide. Ocular axial length (AL) is the major determinant of refraction and thus of myopia and hyperopia. We conducted a meta-analysis of genome-wide association studies for AL, combining 12,531 Europeans and 8,216 Asians. We identified eight genome-wide significant loci for AL (RSPO1, C3orf26, LAMA2, GJD2, ZNRF3, CD55, MIP, and ALPPL2) and confirmed one previously reported AL locus (ZC3H11B). Of the nine loci, five (LAMA2, GJD2, CD55, ALPPL2, and ZC3H11B) were associated with refraction in 18 independent cohorts (n = 23,591). Differential gene expression was observed for these loci in minus-lens-induced myopia mouse …

AdultMaleRefractive errorAdolescentGene ExpressionLocus (genetics)Genome-wide association studyBiologyOcular Axial LengthPolymorphism Single NucleotideWhite PeopleArticle03 medical and health sciences0302 clinical medicineAsian PeopleSDG 3 - Good Health and Well-beingmedicineGeneticsHumansGWASGenetic Predisposition to DiseaseGenetics(clinical)RSPO1Eye ProteinsGeneGenetics (clinical)030304 developmental biologyGenetic associationAgedGenetics0303 health sciencesta1184HeritabilityMiddle Agedta3121medicine.diseaseRefractive ErrorsAxial Length EyeGenetic Loci030221 ophthalmology & optometryEye disorderFemaleGenome-Wide Association StudySignal Transduction
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The dimensions of mobilities: The spatial relationships between corporeal and digital mobilities

2013

Abstract The aim of this article is to study how the corporeal and digital mobilities are spatially organised in relation to each other in everyday life. The dimensions of mobilities are modelled by using survey data (N = 612) collected from Finland in 2011, Multiple Correspondence Analysis (MCA) and Multiple Regression Analysis (MRA). The results show that the combined use of corporeal and digital means of mobility affect the spatial organisation of mobilities only little. The results indicate that young people and students are more likely to benefit from their mobility in networking activities as they are equipped with a larger variety of mobility means than older people and pensioners. L…

AdultMaleWorkAdolescentUrban PopulationSociology and Political ScienceMobilitiesSpatial organisationMovementCombined useTransportationEducationYoung AdultLeisure ActivitiesSex FactorsMultiple correspondence analysisSurveys and QuestionnairesHumansHuman ActivitiesInterpersonal RelationsSociologyta518Everyday lifeFinlandAgedBehaviorModels StatisticalCommunicationAge FactorsSocial Supportta5142Gender studiesMiddle Agedta5141Survey data collectionFemaleSmartphoneElectronicsOlder peopleSocial Science Research
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Point mutations associated with Leber hereditary optic neuropathy in a Latvian population

2013

Purpose To study mutations associated with Leber hereditary optic neuropathy (LHON) in patients suspected of having this mitochondrial disorder in a Latvian population. Additional aims were to determine the heteroplasmy status of all non-synonymous polymorphisms identified in the current study and to identify the mitochondrial haplogroups of the studied participants because these factors may contribute to the manifestation of LHON. Methods Twelve patients, including patients in two families, were enrolled in the current study. LHON was suspected based on the findings of ophthalmologic examinations. In clinically affected individuals, the presence of all previously reported LHON-associated m…

AdultMalecongenital hereditary and neonatal diseases and abnormalitiesPolymorphism Geneticgenetic structuresnutritional and metabolic diseasesOptic Atrophy Hereditary LeberSequence Analysis DNAMiddle AgedDNA MitochondrialLatviaeye diseasesWhite PeopleMitochondriaPedigreeHaplotypesHumansPoint MutationFemaleResearch Article
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Influence of CYP3A5 and ABCB1 gene polymorphisms and other factors on tacrolimus dosing in Caucasian liver and kidney transplant patients

2011

Tacrolimus is a substrate of cytochrome P4503A (CYP3A) enzymes as well as of the drug transporter ABCB1. We have investigated the possible influence of CYP3A5 and ABCB1 single nucleotide polymorphisms (SNPs) and other factors (e.g. albumin, hematocrit and steroids) on tacrolimus blood levels achieved in a population of Caucasian liver (n=51) and kidney (n=50) transplant recipients. At 1, 3 and 6 months after transplantation, tacrolimus doses (mg/kg/day) and trough blood levels (C0) were recorded and the weight-adjusted tacrolimus dosage (mg/kg/day) was calculated. Polymerase chain reaction followed by restriction fragment length polymorphism analysis was used for genotyping CYP3A5*1 and *3 …

AdultMalemedicine.medical_specialtyATP Binding Cassette Transporter Subfamily BGenotypemedicine.medical_treatmentDNA Mutational AnalysisPopulationSingle-nucleotide polymorphismLiver transplantationBiologyKidneyPolymorphism Single NucleotideGastroenterologyBiomarkers PharmacologicalTacrolimusWhite PeopleGene FrequencyInternal medicineGeneticsmedicineCytochrome P-450 CYP3AHumansDrug Dosage CalculationsATP Binding Cassette Transporter Subfamily B Member 1educationAllele frequencyAllelesKidney transplantationAgededucation.field_of_studyKidney metabolismGeneral MedicineMiddle Agedmedicine.diseaseKidney TransplantationTacrolimusLiver TransplantationTransplantationsurgical procedures operativeItalyLiverImmunologySettore BIO/14 - FarmacologiaPharmacogenetics CYP3A5 ABCB1 TacrolimusTransplant patientsFemaleImmunosuppressive AgentsPolymorphism Restriction Fragment LengthInternational Journal of Molecular Medicine
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Lipid subclasses profiles and oxidative stress in aggressive periodontitis before and after treatment

2015

Background and Objective: Associations between dyslipidaemia, oxidative stress and periodontitis have emerged in recent years. However, there is a lack of studies investigating these associations in aggressive periodontitis (AgP) cases. The aim of this study was to investigate the lipid and oxidative stress profiles in patients with AgP, and to relate them to clinical variables and interleukin (IL)-6 genetic variants. Material and Methods: Twelve non-smoking Caucasian patients with AgP selected based on their IL6 haplotypes underwent periodontal non-surgical and surgical treatment. Peripheral blood samples taken at baseline and at six different time-points after treatment were processed to …

AdultMalemedicine.medical_specialtyAdolescentEuropean Continental Ancestry GroupLongitudinal Studiemedicine.disease_causeWhite Peoplechemistry.chemical_compoundYoung AdultGeneticInternal medicinemedicineHaplotypeAggressive periodontitisHumansLongitudinal StudiesPeriodontitismedicine.diagnostic_testCholesterolbusiness.industryInterleukin-6PeriodontitiOxidative Stress.BiomarkerLipidmedicine.diseaseLipidsAggressive PeriodontitiOxidative StressEndocrinologyTreatment OutcomechemistryAggressive PeriodontitisHaplotypesPeriodonticsOxidative strelipids (amino acids peptides and proteins)FemaleMetabolic syndromebusinessLipid profileDyslipidemiaOxidative stressBiomarkersLipoproteinHuman
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The influence of ageing on the force-velocity-power characteristics of human elbow flexor muscles.

2003

Abstract The purpose of this study was to quantify the effects of ageing on the maximal power ( P max ) of the elbow flexor muscles and to determine the impact of velocity on the loss of power in older people. Sixteen elderly subjects (7 men and 9 women, age range 61–78 years) and 17 young subjects (11 men and 6 women, age range 18–27 years) participated in this study. Maximal elbow flexions were performed against increasing inertia. The maximal force ( F max ), maximal shortening velocity ( V max ), P max , dynamic constants ( a , b and a / F max ), optimal force ( F opt ), optimal velocity ( V opt ) and V opt / V max were determined from Hill's equation. Myoelectrical activity (EMG) of th…

AdultMalemedicine.medical_specialtyAgingElbow flexorElbowElectromyographyBiochemistryEndocrinologyAge groupsInternal medicineElbow JointGeneticsmedicineHumansMuscle SkeletalMolecular BiologyMathematicsAgedmedicine.diagnostic_testElectromyographyCell BiologyAnatomyMiddle AgedBiomechanical Phenomenamedicine.anatomical_structureAgeingCardiologyFemaleSexmedicine.symptomOlder peopleForce velocityMuscle contractionMuscle ContractionExperimental gerontology
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