Search results for "Pere"

showing 10 items of 632 documents

Novel isatin-derived molecules activate p53 via interference with Mdm2 to promote apoptosis

2018

International audience; The p53 protein is a key tumor suppressor in mammals. In response to various forms of genotoxic stress p53 stimulates expression of genes whose products induce cell cycle arrest and/or apoptosis. An E3-ubiquitin ligase, Mdm2 (mouse-double-minute 2) and its human ortholog Hdm2, physically interact with the amino-terminus of p53 to mediate its ubiquitin-mediated degradation via the proteasome. Thus, pharmacological inhibition of the p53-Mdm2 interaction leads to overall stabilization of p53 and stimulation of its anti-tumorigenic activity. In this study we characterize the biological effects of a novel class of non-genotoxic isatin Schiff and Mannich base derivatives (…

Isatin0301 basic medicineProgrammed cell deathCell cycle checkpointAntineoplastic AgentsApoptosis[SDV.BC]Life Sciences [q-bio]/Cellular BiologyBiologyPiperazinesHistonesMice03 medical and health scienceschemistry.chemical_compound0302 clinical medicineNutlinCell Line TumorProto-Oncogene ProteinsAnimalsHumansMolecular Biologychemistry.chemical_classificationDNA ligaseIsatinImidazolesISMBDsProto-Oncogene Proteins c-mdm2Cell BiologyNutlinp53-activating moleculesCell biology030104 developmental biologychemistryProteasomeApoptosis030220 oncology & carcinogenesisbiology.proteinMdm2PumaTumor Suppressor Protein p53Apoptosis Regulatory Proteinsautomated microscopy system OperettaResearch PaperDevelopmental BiologyCell Cycle
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Risparmio per investimenti: Crediop, Icipu e lo sviluppo del modello Beneduce

2014

Istituti BeneduceOpere pubblicheSettore SECS-P/12 - Storia EconomicaStoria del sistema bancario italiano
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Oracion panegyrica, declamacion oratoria a los inclytos martyres San Juan de Perusia, y San Pedro de Saxoferrato, patronos de la leal Ciudad de Terue…

1757

Caplletres grav., bandes Sign.: A20 Text amb postil·les marginals Reclams

Joan de Perusa (O.F.M.) Sermons Obres anteriors a 1800Sermons castellans Terol (Aragó) S.XVIII Obres anteriors a 1800Pere de Sassoferrato (O.F.M.) Sermons Obres anteriors a 1800
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Zur Rolle des Deutschen aus der Sicht von Studierenden in Finnland eine Umfrage unter den Studierenden der Universitäten Jyväskylä und Tampere

2008

Jyväskylän yliopistosaksan kielikorkeakouluopiskelukielitaitomonikielisyysTampereen yliopistoopiskelijavaihtoyliopistot
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Kultivēšanas barotņu un Tween surfaktanta ietekme uz Trichoderma asperellum biomasas kvalitāti un tās uzglabāšanas ilgumu

2022

Pētījuma mērķis bija novērtēt dažādu pēc sastāva kultivēšanas barotņu un Tween surfaktanta ietekmi uz Trichoderma asperellum biomasas kvalitāti un tās uzglabāšanas ilgumu. Pētījumā tika novērtēta dažādu koncentrāciju Tween 20, 40 un 80 ietekme uz T. asperellum morfoloģiskās struktūras un sausās biomasas izmaiņām, kā arī kultivēšanas šķidruma antifungālā iedarbība pret fitopatogēnu Cladosporium herbarum. Optimālākais Tween surfaktanta veids un koncentrācija, kas eksperimentāli tika noteikts kā Tween 80 ar 0,2% koncentrāciju, tika pievienots T. asperellum dziļumkultivācijas procesam 15 litru bioreaktorā, fermentācijas procesos izmantojot 4 dažādas barotnes – iesala ekstrakta, saharozes – raug…

KVVTweenBioloģijaT. asperellumUzglabāšanaKūdra
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Kalmbergin kartasto R III : List 8

1855

KangasalaPälkäneMessukyläTampereOrivesiLempääläVesilahtimaastokartat1850-lukuSahalahtiPirkkalakartat
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The Song of the Crusade against the Albigensians (1st quarter of the 13th century) and the Treaty of Meaux-Paris (1228). Literary mimesis and legal c…

2020

En aquest article analitzem els mecanismes de la construcció del relat (oficial), des de diversos punts de vista, de la Croada contra els albigesos i l’expoli d’Occitània per França en el transcurs d’aqueixa cruel campanya militar (1r terç del segle XIII). Analitzarem dues fonts textuals que són testimonis d’excepció dels fets i de la construcció i la narració d’aqueix relat, a través de la mimesi historiogràfica en un cas, la Cançó de la Croada contra els albigesos, i, en l’altre, del formalisme d’un text jurídic (document històric, pròpiament dit) del més alt rang, el Tractat de Meux-París (1229), signat pels màxims representants de les dues contraparts. I també analitzarem qui es benefic…

King Peter The Catholic of AragonHistoryLiterature and Literary TheoryKing Louis IX of Francemedia_common.quotation_subjectRamon VII de TolosaBatalla de MuretLanguage and LinguisticsCançó de la Croada contra els albigesosRaymund VII of ToulouseTractat de Meaux-París (1229)Filología CatalanaSong of the Crusade againts the CatarsTreaty of Meaux-Paris (1229)media_commonUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASHistoriografia medievalHistoriographyPere el CatólicoArtAlfons de Poitiers:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]Battle of MuretMedieval HistoriographyLluís IX de FrançaHumanitiesAlphons de Poitiers
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Bezpieczne granice - wolny obywatel

2015

Konwencja SchengenUmowa z SaarbruckenProgram HaskiTraktat LizbońskiProgram SztokholmskiKonwencja DublińskaUkład z SchengenTraktat AmsterdamskiProgram z Tampereswoboda przemieszczania się
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Verità e ambiguità della favola nella "Storia del genere umano"

2009

Lettura della "Storia del genere umano" di Giacomo Leopardi

Leopardi. Operette morali
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De l’effet transformatif de l’imaginaire :

2019

The polymorphic concept of the novel and the intertextuality of the literary genres characterize the work of Georges Perec, whose writing looks into different genres, codes and models and combines them in order to preserve the singularity of each of his works. Among these W ou le souvenir d’enfance, an unclassifiable novel that alternates fiction and childhood memories, has been the result of a very difficult writing process, that genetic documents can only partly clear up. We propose to reflect on the process of re-functionalization of the adventure novel W, which appeared before as a serialized text in the journal La Quinzaine littéraire and was then integrated into the great autobiograph…

Linguistics and LanguageHistoryLiterature and Literary Theoryre-fonctionnalisation Perec (Georges) intertextualité générique récit d’enfance autobiographieSettore L-LIN/03 - Letteratura FranceseLanguage and Linguisticsre-functionalization Perec (Georges) intertextuality childhood memories AutobiographyRevue italienne d’études françaises
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