Search results for "Periradicular"
showing 7 items of 7 documents
Inflammatory Response Mechanisms of the Dentine–Pulp Complex and the Periapical Tissues
2021
The macroscopic and microscopic anatomy of the oral cavity is complex and unique in the human body. Soft-tissue structures are in close interaction with mineralized bone, but also dentine, cementum and enamel of our teeth. These are exposed to intense mechanical and chemical stress as well as to dense microbiologic colonization. Teeth are susceptible to damage, most commonly to caries, where microorganisms from the oral cavity degrade the mineralized tissues of enamel and dentine and invade the soft connective tissue at the core, the dental pulp. However, the pulp is well-equipped to sense and fend off bacteria and their products and mounts various and intricate defense mechanisms. The fron…
Immunohistochemical study of Langerhans cells in periapical lesions: correlation with inflammatory cell infiltration and epithelial cell proliferatio…
2008
Aim: The aim of this study is to determine the presence and distribution of Langerhans cells in periapical lesions, and correlate this with inflammatory cell infiltration and epithelial cell proliferation. Material and Methods: Seventy chronic dental periradicular lesions, obtained during periapical surgery from 70 patients, were included in this study, including: 46 granulomas, 18 scar tissue and 6 periradicular cysts. Immunohistochemical staining was performed using the following markers: CD3 to analyze the inflammatory infiltrate, CD1a to determine the presence of Langerhans cells and Ki67 to analyze the epithelial cell proliferation. The CD1a immunostaining density was established follo…
Influence of a bioceramic root end material and mineral trioxide aggregates on fibroblasts and osteoblasts
2012
The biocompatibility of materials used in endodontic treatment is of high importance, because they can come in contact with periradicular tissues and there is a risk of possible systemic toxicity. The aim of the present study was to investigate the in vitro reaction to a bioceramic based root end material in comparison to mineral trioxide aggregates (MTA) as the established gold standard.The root end materials grey MTA Angelus (GMTA), white MTA Angelus (WMTA), ProRoot MTA, and EndoSequence Root Repair Material (ERRM) were incubated with human periodontal ligament fibroblasts and osteoblasts (10(4)cells/ml) for up to 96h. Cell proliferation (RFU) was determined by means of the Alamar Blue as…
Innovations in endodontic filling materials
2012
One of the goals of endodontic treatment is to achieve a complete, tridimensional, hermetic sealing of the root canal system to prevent the entry of microorganisms or their products through both the coronal and apical pathways. Gutta-percha is the most widely used material for root canal filling and despite its numerous properties, such as biocompatibility and thermoplasticity, it has however an important limit: the lack of adhesion to the canal walls. Attempts to address this problem have been made over the years by using endodontic cements capable of bonding to canal dentine but their tendency to resorption in time can compromise the quality of treatment. The first step towards a real adh…
Evaluation of antibacterial efficacy of Chitosan, Chlorhexidine, Propolis and Sodium hypochlorite on Enterococcus faecalis biofilm : an in vitro study
2017
Background Long term successful root canal treatment requires effective debridement and disinfection of root canal system. Persistent periradicular lesions are usually associated with Enterococccus faecalis. Prompt research for natural alternatives for irrigation is mainly due to the constant increase in antibiotic resistant strains and side effects caused by synthetic drugs. Sodium hypochlorite; the gold standard for irrigation has many disadvantages. Therefore, the present study was aimed to explore newer irrigants probably be as more effective and at the same time would be less irritating to the tissues than NaOCl. Material and methods Ninety extracted human mandibular premolars were bio…
Endodontic management of single rooted immature mandibular second molar with single canal using MTA and platelet-rich fibrin membrane barrier: A case…
2011
An immature tooth with pulpal necrosis and periapical pathology imposes a great difficulty to the endodontists. Endodontic treatment options for such teeth consist of conventional apexification procedure with and without apical barriers. Various materials have been tried as apical matrix in the past. This article demonstrates the newer concept of using platelet rich fibrin membrane as an apical matrix barrier for stabilization of MTA in root end apexification procedure. Platelet Rich Fibrin is an autologous fibrin matrix containing a large quantity of platelet and leukocyte cytokines, which enhance healing by release of growth factors. This case report represents successful management of a …
Apikālā periodontīta sastopamības biežums un endodontikās ārstēšanas kvalitāte pieaugušo izvēlētā populācijā Latvijā
2022
Apikālais periodontīts (AP) ir izplatīta hroniska iekaisuma slimība, kas izpaužas kā dinamiska organisma aizsargreakcija pret mikrobu infekciju zobu sakņu kanālu sistēmā. Pētījumi liecina, ka AP ir plaši izplatīts pieaugušajiem - vismaz viens zobs ar AP ir 27 - 80% pieaugušo (Kirkevang & Vaeth, 2019). AP ir tieša saistība ar sakņu kanālu ārstēšanas kvalitāti – nekvalitatīva ārstēšana tiek saistīta ar palielinātu AP izplatību (Chala et al., 2011; Meirinhos et al., 2020). Darba mērķis bija izpētīt apikālā periodontīta izplatību un endodontiskās ārstēšanas biežumu un kvalitāti izvēlētā Latvijas pieaugušo populācijā.