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showing 10 items of 3924 documents

Dopamine D2 Receptor Occupancy Estimated From Plasma Concentrations of Four Different Antipsychotics and the Subjective Experience of Physical and Me…

2019

Background Impaired subjective well-being in schizophrenia patients treated with antipsychotics has often been linked inter alia to the antidopaminergic effects of medication. Thus, it is important to capture the association between striatal dopamine D2 receptor occupancy (D2-RO) and global subjective well-being. We examined this association using data from our multicenter, randomized, double-blind Neuroleptic Strategy Study (NeSSy). Methods An innovative double randomization process was used for allocation of patients to the specific treatment groups. Plasma drug concentrations were measured after 6 and 24 weeks of treatment to obtain the estimated D2-RO (eD2-RO) relative to literature val…

AdultMaleOlanzapinemedicine.medical_specialtymedicine.medical_treatmentAripiprazolePersonal SatisfactionMedication Adherencelaw.invention03 medical and health sciencesSex Factors0302 clinical medicineDouble-Blind MethodRandomized controlled triallawInternal medicinemedicineHaloperidolHumansPharmacology (medical)AntipsychoticReceptors Dopamine D2business.industryMiddle Agedmedicine.disease3. Good health030227 psychiatryFlupentixolFlupenthixolDopamine D2 Receptor AntagonistsPsychiatry and Mental healthOlanzapineSchizophreniaQuality of LifeSchizophreniaHaloperidolQuetiapineFemaleSchizophrenic PsychologyAripiprazolebusiness030217 neurology & neurosurgeryAntipsychotic Agentsmedicine.drugJournal of Clinical Psychopharmacology
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The international phase 4 validation study of the EORTC QLQ-SWB32: A stand-alone measure of spiritual well-being for people receiving palliative care…

2017

The EORTC Quality of Life Group has just completed the final phase (field‐testing and validation) of an international project to develop a stand‐alone measure of spiritual well‐being (SWB) for palliative cancer patients. Participants (n = 451)—from 14 countries on four continents; 54% female; 188 Christian; 50 Muslim; 156 with no religion—completed a provisional 36‐item measure of SWB plus the EORTC QLQ‐C15‐PAL (PAL), then took part in a structured debriefing interview. All items showed good score distribution across response categories. We assessed scale structure using principal component analysis and Rasch analysis, and explored construct validity, and convergent/divergent validity with …

AdultMalePalliative careAdolescentEmotionsmeasureIslamChristianityspiritualYoung Adult03 medical and health sciencesInterpersonal relationship0302 clinical medicineQuality of life (healthcare)NeoplasmsSurveys and QuestionnairesHumansMedicineInterpersonal RelationsSpirituality030212 general & internal medicineAgedAged 80 and overRasch modelbusiness.industryquestionnaireDebriefingPalliative CareReligion and MedicineDiscriminant validityReproducibility of ResultsConstruct validityMiddle AgedEORTCOncologyinternational030220 oncology & carcinogenesisWell-beingQuality of LifeFemalebusinessClinical psychologyEuropean journal of cancer care
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Development and Validation of a New Tool for the Assessment and Spiritual Care of Palliative Care Patients

2013

Context. Spiritual assessment tools and interventions based on holistic approaches are needed to promote healing. Such tools must be adapted to the wide cultural backgrounds of contemporary Western society. Objectives. To develop and validate a new brief measure, simultaneously featuring clinical applicability and adequate psychometric properties. The tool uses six initial questions to establish a climate of trust with patients before they complete an eight-item, five-point Likert scale. The questionnaire is based on a model of spirituality generated by the Spanish Society of Palliative Care (SECPAL) Task Force on Spiritual Care (Grupo de Espiritualidad de la SECPAL), which aims to recogniz…

AdultMalePalliative carePsychometricsassessmentPilot ProjectsContext (language use)Models Psychologicalstructural equation modelingLikert scaleNursingSurveys and QuestionnairesCriterion validityHumansMedicineSpiritualityquestionnaire validationGeneral NursingAgedAged 80 and overbusiness.industryPalliative CareReproducibility of ResultsConstruct validityMiddle AgedspiritualityConfirmatory factor analysisCross-Sectional StudiesAnesthesiology and Pain MedicineSpainspiritual carePalliative careFemaleNeurology (clinical)Spiritual careFactor Analysis StatisticalbusinessIntrapersonal communicationJournal of Pain and Symptom Management
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Functional pain in hospitalised and school children

2012

Aim. Aim of the study was to recognise the role of psychological disagreement in children and adolescents suffering from functional pain. Methods. Two groups of children, adolescents and their parents were interviewed: group H (hospitalized patients), group S (students, at school). Suitable investigations excluded organic lesions. The following data were analysed: 1) presence of pain in relation with: i) sex and age; ii) relation with parents, brothers, other relatives, schoolfellows; 2) efficacy of possible treatments. Results. Group H: 194 patients, median age 10 years; 134 referred pain: 62 out of 92 males and 72 out of 102 females; location of pain: abdomen, limbs, head, back. Family di…

AdultMaleParentsAdolescentPainPeer GroupSex FactorsSettore MED/38 - Pediatria Generale E SpecialisticaRisk FactorsSurveys and QuestionnairesPrevalenceHumansInterpersonal RelationsChildStudentsSicilyPain MeasurementInpatientsSchoolsAge FactorsHeadacheBullyingArthralgiaAbdominal PainFemaleLow Back PainAlgorithms
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Stability in MMPI among adoptees with high and low genetic risk for schizophrenia and with low Communication Deviance of their adoptive parents.

2013

Abstract Stability has been considered an important aspect of vulnerability to schizophrenia. The temporal stability of the scales in the Minnesota Multiphasic Personality Inventory (MMPI) was examined, using adoptees from the Finnish Adoptive Family Study of Schizophrenia. Adoptees who were high-risk (HR) offspring of biological mothers having a schizophrenia spectrum disorder ( n =28) and low-risk (LR) controls ( n =46) were evaluated using 15 MMPI scales at the initial assessment (HR, mean age 24 years; LR, mean age 23 years) and at the follow-up assessment after a mean interval of 11 years. Stability of the MMPI scales was also assessed in the groups of adoptees, assigned according to t…

AdultMaleParentsParanoid schizophreniaAdolescentHostilityAdoption studyEnvironmentDevelopmental psychologyYoung AdultCommunication devianceMinnesota Multiphasic Personality InventoryMMPIPsychoticismmental disordersAdoptionmedicineHumansta515Biological PsychiatryFinlandAnalysis of VarianceCommunicationmedicine.diseasePsychiatry and Mental healthHypomaniaSchizophreniaSchizophreniaFemaleSchizophrenic Psychologymedicine.symptomPsychologyPersonalityPsychiatry research
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Factors associated with poor adherence to MMR vaccination in parents who follow vaccination schedule.

2014

Due to median vaccination coverage far from elimination level, Italy is still an European country with high number of measles cases per million of people. In this study we explored potential socioeconomic, medical and demographic factors which could influence the propensity of family members for measles vaccination schedule. A cross-sectional study was performed through a questionnaire administered to the parents of children who received the first dose of MMR vaccine in two different vaccination centers in the Palermo area from November 2012 to May 2013. Overall, the role played by internet (OR 19.8 P = 0.001) and the large number of children in a family (OR 7.3 P ≤ 0.001) were the factors …

AdultMaleParentsPediatricsmedicine.medical_specialtyMeasles-Mumps-Rubella VaccineVaccination scheduleCross-sectional studyImmunologyMMR vaccineSettore MED/42 - Igiene Generale E ApplicataMeaslesMedication AdherencechildrenSurveys and QuestionnairesmedicineImmunology and AllergyHumansmeaslebirth orderSocioeconomic statusPharmacologypersonal decisionbusiness.industryVaccinationInfant NewbornInfantmedicine.diseaseVaccinationBirth orderCross-Sectional Studiesvaccination refuseSocioeconomic FactorsItalyfamily memberChild PreschoolFemaleinternetbusinessMeasles-Mumps-Rubella VaccineDemographyResearch PaperMeasles
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Parental satisfaction with children's primary dental care in Valencia, Spain.

2011

Aim To evaluate parents’ satisfaction with the dental care that their children received in a primary dental care unit in Valencia, Spain. Methods A cross-sectional study was designed. Parents were given a self-administered questionnaire with questions on accessibility, information received from the dentist and hygienist, staff interest in their child, dentist's and hygienist's apparent professional competence, handling of the child's behaviour, cleanliness of the office (surgery), overall parent satisfaction, parent's and child's age, and parental educational level. The chi-square test was used to assess overall parental satisfaction and the other study variables. For the multivariant study…

AdultMaleParentsPediatricsmedicine.medical_specialtyTime FactorsAdolescentDentistsChild BehaviorPersonal SatisfactionHealth Services AccessibilityAppointments and SchedulesYoung AdultmedicineHumansChildDental Care for ChildrenPrimary Health Carebusiness.industryCommunicationAge FactorsHygieneGeneral MedicineProfessional-Patient RelationsMiddle AgedDental careDental care deliveryCross-Sectional StudiesSpainFamily medicineChild PreschoolEducational StatusHealth Education DentalFemaleClinical CompetenceDental HygienistsbusinessAttitude to HealthPrimary dental care : journal of the Faculty of General Dental Practitioners (UK)
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Interaction of genetic vulnerability to schizophrenia and Communication Deviance of adoptive parents associated with MMPI schizophrenia vulnerability…

2008

The aim of this study was to establish possible genotype-environment interaction in high-risk and low-risk adoptees' vulnerability to schizophrenia. The study population consisted of a subgroup of 41 adoptive families with a high genetic risk adoptee and 58 families with a low genetic risk adoptee from the Finnish Adoptive Family Study of Schizophrenia. Communication style was assessed based on the Communication Deviance (CD) of the adoptive parents, and the adoptees' vulnerability indicators were measured with the Minnesota Multiphasic Personality Inventory (MMPI). Taken separately, only the genetic liability to schizophrenia, but not the communication style of the adoptive parents, was si…

AdultMaleParentsmedicine.medical_specialtyAdolescentGenotypeSchizophrenia (object-oriented programming)VulnerabilityHostilityEnvironmentSeverity of Illness IndexDevelopmental psychologyMinnesota Multiphasic Personality InventoryCommunication devianceMMPIAdoptionmedicineHumansGenetic Predisposition to DiseaseGenetic riskPsychiatryGenetic vulnerabilityCommunicationPsychiatry and Mental healthSchizophreniaPopulation studyFemalemedicine.symptomPsychologyNordic journal of psychiatry
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Nursing staff interactions during the older residents' transition into long-term care facility in a nursing home in rural Norway: an ethnographic stu…

2015

Background: Future challenges in many countries are the recruitment of competent staff in long-term care facilities, and the use of unlicensed staff. Our study describes and explores staff interactions in a long-term care facility, which may facilitate or impede healthy transition processes for older residents in transition. Methods: An ethnographic study based on fieldwork following ten older residents admission day and their initial week in the long-term care facility, seventeen individual semi-structured interviews with different nursing staff categories and the leader of the institution, and reading of relevant documents. Results: The interaction among all staff categories influenced th…

AdultMalePatient TransferRural PopulationHealth PersonnelEthnographyLong-term care facilityYoung AdultStaff interactionsHomes for the AgedHumansInterpersonal RelationsAnthropology CulturalAgedAged 80 and overResidentNorwayHealth PolicyMiddle AgedPatient Acceptance of Health CareLong-Term CareNursing Homes808Complexity scienceTransitionFemaleResearch Article
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Effects of age on depressive symptomatology and response to antidepressant treatment in patients with major depressive disorder aged 18 to 65 years

2020

Background: There is evidence that symptomatology in patients with major depressive disorder (MDD) changes with age. However, studies comparing depressive symptomatology between different age groups during antidepressant therapy are rare. We compared demographic and clinical characteristics in depressed patients of different age groups at baseline and during treatment. Methods: 889 MDD inpatients were divided into four age groups (18–29, 30–39, 40–49, 50–65 yrs.). Demographic and clinical characteristics including depressive symptomatology (assessed by the Inventory of Depressive Symptoms) were assessed at baseline and weekly during treatment. Results: At baseline, young patients (18–29 yea…

AdultMalePediatricsmedicine.medical_specialtyAdolescentlcsh:RC435-571IrritabilityDepressive symptomatology03 medical and health sciencesYoung Adult0302 clinical medicinelcsh:PsychiatrymedicineHumansIn patientDepression (differential diagnoses)AgedDepressive Disorder Majorbusiness.industryDepressionAge FactorsMiddle Agedmedicine.diseasePersonality disordersAntidepressive AgentsIrritable MoodSelf Concept030227 psychiatrySubstance abusePsychiatry and Mental healthClinical PsychologyTreatment OutcomeAntidepressantMajor depressive disorderFemalemedicine.symptombusiness030217 neurology & neurosurgeryComprehensive Psychiatry
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