Search results for "Pharmaceutical Science"

showing 2 items of 2702 documents

Biodegradable Metal-Organic Framework-Based Microrobots (MOFBOTs).

2020

Microrobots and metal–organic frameworks (MOFs) have been identified as promising carriers for drug delivery applications. While clinical applications of microrobots are limited by their low drug loading efficiencies and the poor degradability of the materials used for their fabrication, MOFs lack motility and targeted drug delivery capabilities. The combination of these two fields marks the beginning of a new era; MOF‐based small‐scale robots (MOFBOTs) for biomedical applications. Yet, biodegradability is a major hurdle in the field of micro‐ and nanoswimmers including small‐scale robots. Here, a highly integrated MOFBOT that is able to realize magnetic locomotion, drug delivery, and selec…

zeolitic imidazolate frameworksMaterials scienceBiomedical EngineeringPharmaceutical ScienceNanotechnology02 engineering and technology010402 general chemistrybiodegradation01 natural sciencesBiomaterialsmetal–organic frameworksDrug Delivery SystemsNeoplasmsHumansMetal-Organic FrameworksBiodegradable metal021001 nanoscience & nanotechnologyControlled release0104 chemical sciencesMagnetic FieldsTargeted drug deliverySelective degradationDoxorubicindrug deliveryDrug deliverybiodegradation; drug delivery; metal–organic frameworks; microrobots; zeolitic imidazolate frameworksChemotherapeutic drugs0210 nano-technologymicrorobotsAdvanced healthcare materials
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Chemical Composition of the Essential Oil of Bupleurum Fontanesii (Apiaceae) Growing Wild in Sicily and its Activity on Microorganisms Affecting Hist…

2016

Hydrodistillation of the flowers (BpFl) of and fruits (BpFr) of Bupleurum fontanesii Guss. ex Caruel gave two oils that were analyzed by GC and GC-MS. The main components were α-elemol (16.7%), caryophyllene oxide (16.4%) and heptacosane (15.9%) in BpFl, and spathulenol (16.8%), caryophylladienol I (13.2%) and α-elemol (12.8%) in BpFr. A good antimicrobial activity against several microorganisms, including Bacillus subtilis, Staphylococcus aureus, Fusarium oxysporum and Aspergillus niger, all infesting historical art craft, was also determined.

α-ElemolBupleurumAntifungal AgentsMicroorganismPlant ScienceBacillus subtilis01 natural scienceslaw.inventionlawVolatile componentDrug DiscoveryBotanyFusarium oxysporumOils VolatilePlant OilsSicilyEssential oilPharmacologyApiaceaeBacteriaBupleurum fontanesiibiology010405 organic chemistryDrug Discovery3003 Pharmaceutical ScienceAspergillus nigerFungiSpathulenolfood and beveragesGeneral MedicineComplementary and Alternative Medicine2708 DermatologyAntimicrobialbiology.organism_classificationAnti-Bacterial AgentsBupleurum0104 chemical sciences010404 medicinal & biomolecular chemistryCaryophyllene oxideComplementary and alternative medicineArtApiaceaeNatural Product Communications
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