Search results for "Phenol"

CCDC 687036: Experimental Crystal Structure Determination

2011

Related Article: S.Banerjee, M.Nandy, S.Sen, S.Mandal, G.M.Rosair, A.M.Z.Slawin, C.J.G.Garcia, J.M.Clemente-Juan, E.Zangrando, N.Guidolin, S.Mitra|2011|Dalton Trans.|40|1652|doi:10.1039/c0dt00923g

CCDC 866944: Experimental Crystal Structure Determination

2013

Related Article: E.Colacio, J.Ruiz, A.J.Mota, M.A.Palacios, E.Ruiz, E.Cremades, M.M.Hanninen, R.Sillanpaa, E.K.Brechin|2012|Comptes Rendus Chimie|15|878|doi:10.1016/j.crci.2012.08.001

CCDC 664106: Experimental Crystal Structure Determination

2010

Related Article: A.Ray, C.Rizzoli, G.Pilet, C.Desplanches, E.Garribba, E.Rentschler, S.Mitra|2009|Eur.J.Inorg.Chem.||2915|doi:10.1002/ejic.200900188

Catalytic epoxidation using dioxidomolybdenum(VI) complexes with tridentate aminoalcohol phenol ligands

2019

Reaction of the tridentate aminoalcohol phenol ligands 2,4-di-tert-butyl-6-(((2 hydroxyethyl)(methyl)amino)methyl)phenol (H2L1) and 2,4-di-tert-butyl-6-(((1-hydroxybutan-2-yl)amino)methyl)phenol (H2L2) with [MoO2(acac)2] in methanol solutions resulted in the formation of [MoO2(L1)(MeOH)] (1) and [MoO2(L2)(MeOH)] (3), respectively. In contrast, the analogous reactions in acetonitrile afforded the dinuclear complexes [Mo2O2(μ-O)2(L1)2] (2) and [Mo2O2(μ-O)2(L2)2] (4). The corresponding reactions with the potentially tetradentate ligand 3-((3,5-di-tert-butyl-2-hydroxybenzyl)(methyl)amino)propane-1,2-diol (H3L3) led to the formation of the mononuclear complex [MoO2(L3)(MeOH)] (5) in methanol whi…

Regioselective Metal- and Reagent-Free Arylation of Benzothiophenes by Dehydrogenative Electrosynthesis.

2018

A novel strategy for the synthesis of biaryls consisting of a benzothiophene and a phenol moiety is reported. These heterobiaryls are of utmost interest for pharmaceutical, biological, and high-performance optoelectronic applications. The metal- and reagent-free, electrosynthetic, and highly efficient method enables the generation of 2- and 3-(hydroxyphenyl)benzo[b]thiophenes in a regioselective fashion. The described one-step synthesis is easy to conduct, scalable, and inherently safe. The products are afforded in high yields of up to 88 % and with exquisite selectivity. The reaction also features a broad scope and tolerates a large variety of functional groups.

Conformational Switching of Multi-Responsive Ferrocenyl-Phenol Conjugates

2016

Multifunctional conformational switches based on the ferrocenyl-salicylic acid amide motif with increasing additional complexity at the Fc moiety (R = COOMe, CONHEt, CONHFc; H-2–H-4; Fc = ferrocenyl) have been prepared and their preferred secondary structures in solution have been elucidated by NMR and IR spectroscopy in combination with conformational searches based on DFT calculations. Their distinct conformational responses to deprotonation ([2]––[4]–) and oxidation ([H-2]+·–[H-4]+·) have been revealed by IR, EPR, and UV/Vis spectroscopy as well as by DFT calculations. Deprotonation inverts all amide units (double amide twist) whereas oxidation selectively flips the terminal amide unit (…

Metal- and Reagent-Free Anodic C−C Cross-Coupling of Phenols with Benzofurans leading to a Furan Metathesis

2018

Heterobiaryls consisting of a phenol and a benzofuran motif are of significant importance for pharmaceutical applications. An attractive sustainable, metal- and reagent-free, electrosynthetic, and highly efficient method, that allows access to (2-hydroxyphenyl)benzofurans is presented. Upon the electrochemical dehydrogenative C-C cross-coupling reaction, a metathesis of the benzo moiety at the benzofuran occurs. This gives rise to a substitution pattern at the hydroxyphenyl moiety which would not be compatible by a direct coupling process. The single-step protocol is easy to conduct in an undivided electrolysis cell, therefore scalable, and inherently safe.

Catalytic Carbonylative Double Cyclization of 2-(3-Hydroxy-1-yn-1-yl)phenols in Ionic Liquids Leading to Furobenzofuranone Derivatives

2019

A catalytic carbonylative double cyclization method for the synthesis of furo[3,4-b]benzofuran-1(3H)-ones is reported. It is based on the reaction between readily available 2-(3-hydroxy-1-yn-1-yl)phenols, CO, and oxygen carried out in the presence of catalytic amounts of PdI2 (1 mol %) in conjunction with KI (20 mol %) and 2 equiv of diisopropylethylamine at 80 degrees C for 24 h under 30 atm of a 1:4 mixture of CO-air. Interestingly, the process was not selective when carried out in classical organic non-nucleophilic solvents (such as MeCN or DME), leading to a mixture of the benzofurofuranone derivative and the benzofuran ensuing from simple cycloisomerization, whereas it turned out chemo…

2020

Teraryl-based alpha-helix mimetics have resulted in efficient inhibitors of protein-protein interactions (PPIs). Extending the concept to even longer oligoarene systems would allow for the mimicking of even larger interaction sites. We present a highly efficient synthetic modular access to quateraryl alpha-helix mimetics, in which, at first, two phenols undergo electrooxidative dehydrogenative cross-coupling. The resulting 4,4′-biphenol is then activated by conversion to nonaflates, which serve as leaving groups for iterative Pd-catalyzed Suzuki-cross-coupling reactions with suitably substituted pyridine boronic acids. This work, for the first time, demonstrates the synthetic efficiency of …

Optimizing Gaussian Process Regression for Image Time Series Gap-Filling and Crop Monitoring

2020

Image processing entered the era of artificial intelligence, and machine learning algorithms emerged as attractive alternatives for time series data processing. Satellite image time series processing enables crop phenology monitoring, such as the calculation of start and end of season. Among the promising algorithms, Gaussian process regression (GPR) proved to be a competitive time series gap-filling algorithm with the advantage of, as developed within a Bayesian framework, providing associated uncertainty estimates. Nevertheless, the processing of time series images becomes computationally inefficient in its standard per-pixel usage, mainly for GPR training rather than the fitting step. To…