Search results for "Phlorhizin"

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Pharmacological research on natural substances in Latvia: Focus on lunasin, betulin, polyprenol and phlorizin

2016

In this concise review the current research in plant bioactive compound studies in Latvia is described. The paper summarizes recent studies on substances from edible plants (e.g., cereals and apples) or their synthetic analogues, such as peptide lunasin, as well as substances isolated from inedible plants (e.g., birch and conifer), such as pentacyclic triterpenes (e.g., betulin, betulinic acid, and lupeol) and polyprenols. Latvian researchers have been first to demonstrate the presence of lunasin in triticale and oats. Additionally, the impact of genotype on the levels of lunasin in cereals was shown. Pharmacological studies have revealed effects of lunasin and synthetic triterpenes on the …

0301 basic medicinePhlorizinPharmacologyLunasinTerpene03 medical and health scienceschemistry.chemical_compoundPolyprenolHemiterpenesPentanolsBetulinic acidAnimalsHumansPlant ProteinsLupeolPharmacologyBiological ProductsBetulinLatviaTriterpenesBioactive compoundPhlorhizin030104 developmental biologychemistryBiochemistryPlants EdiblePharmacological Research
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Metabolic aspects of the rhythmogenesis inAplysia pacemaker neurons

1973

Completely isolatedAplysia pacemaker neurons were used to investigate mechanisms of endogenous electrical rhythmicity. This preparation allows the study of pure pacemaker activity free from synaptic, ephaptic and/or humoral influences from the surrounding cells. The effect of some substances quite different in their mode of biochemical action were tested: sodium iodoacetate, phloridzin, dinitrophenol, heavy water, and ouabain. Each of these substances suppressed the spontaneous spike activity without any marked depolarizing or hyperpolarizing effect. Spontaneous spike activity of the neurons silenced after addition of one of these substances reappeared after addition of glucose. The restori…

Periodicitymedicine.medical_specialtyPhysiologyEphaptic couplingClinical BiochemistryAction PotentialsIodoacetatesEndogenyBiologyOuabainAdenosine TriphosphateATP hydrolysisPhysiology (medical)Internal medicinemedicineAnimalsGlycolysisOuabainNeuronsHydrolysisSodiumDepolarizationDeuteriumbiology.organism_classificationCell biologyGlucosePhlorhizinEndocrinologyMolluscaAplysiaDinitrophenolGlycolysisDinitrophenolsmedicine.drugPflügers Archiv
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