Search results for "Phobia"

showing 10 items of 205 documents

Fluvoxamine or placebo in the treatment of panic disorder and relationship to blood concentrations of fluvoxamine.

1998

A six-week double-blind placebo-controlled trial of fluvoxamine was undertaken in 46 patients suffering from panic disorder with or without agoraphobia diagnosed by DSM-III-R guidelines. Average daily dosage of fluvoxamine was 160 mg, with a highest permitted dose of 300 mg/day. Weekly evaluation included a diary in which the number, severity, and duration of full-blown and limited panic attacks and the duration and severity of anticipating fear, CAS, GAS, CGI, HAM-D, adverse effects and the number of capsules not taken were noted. Fluvoxamine was not significantly superior to placebo with regard to the main outcome criterion, i.e., the reduction in the number of panic attacks, but it was s…

AdultMaleAdolescentFluvoxaminePlacebolaw.inventionRandomized controlled trialDouble-Blind Methodlawmental disordersmedicineHumansPharmacology (medical)Adverse effectAgedPsychiatric Status Rating ScalesPanic disorderPanicGeneral MedicineMiddle Agedmedicine.diseasehumanitiesPsychiatry and Mental healthAnti-Anxiety AgentsFluvoxamineAnesthesiaPanic DisorderFemalemedicine.symptomDrug MonitoringPsychologyAnxiety disorderSelective Serotonin Reuptake Inhibitorsmedicine.drugAgoraphobiaPharmacopsychiatry
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Spanish Adaptation and Validation of the Short Internalized Homonegativity Scale (SIHS)

2016

Internalized homophobia has been related to mental health problems and sexual risk behaviors among nonheterosexual people. This article validates the Spanish adaptation of the Short Internalized Homonegativity Scale (SIHS). For this purpose, 347 men and 183 women completed the instrument. Exploratory factorial analysis showed three factors: public identification as homosexual (PIH), sexual comfort with homosexual people (SEXC), and social comfort with homosexual people (SOCC). These factors explained 57.96% of total variance. In addition, confirmatory factorial analysis supported this structure and internal consistency (Cronbach's alpha) was.80 for the full scale. The three subscales ranged…

AdultMaleAdolescentPsychometricseducationPatient Health QuestionnaireDevelopmental psychologylaw.inventionNonheterosexual peopleYoung Adult03 medical and health sciences0302 clinical medicine0504 sociologyCondomCronbach's alphalawSurveys and QuestionnairesShort Internalized Homonegativity Scale (SIHS)Mental health problemsHumansInternal-External ControlSexual riskAged05 social sciences050401 social sciences methodsHomosexualityMiddle AgedMental healthSelf Concept030227 psychiatrySpanish populationClinical PsychologyMental HealthConvergent validitySpainScale (social sciences)FemaleHomophobiaFactorial analysisFactor Analysis StatisticalPsychologySexual riskSpanish population
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Harassment patterns and risk profile in Spanish trans person

2017

This article describes the harassment patterns and the risk profile in trans people living in Spain. A sample of 212 trans persons, aged 10-62, participated in this cross-sectional study. Results showed a high percentage of harassment (59.9%) and frequency of daily harassment (12.6%), especially verbal attacks (59%) that occurred in public spaces (49.1%) and within educational contexts (46.2%). Harassment is more prevalent in trans women than men. Those who disclose their gender identities at a younger age experience higher percentages and frequency of harassment than those who disclose at an older age. They also suffer more harassment of different types. The risk profile of harassment indi…

AdultMaleAdolescentSocial PsychologyPoison control050109 social psychologyTransgender PersonsSuicide preventionOccupational safety and healthEducationGender StudiesYoung AdultTransgenderInjury preventionPrevalenceHumansMedicine0501 psychology and cognitive sciencesChildSocial BehaviorGeneral PsychologyTranssexualitatbusiness.industryMental Disorders05 social sciencesGender IdentityHuman factors and ergonomicsGeneral MedicineMiddle AgedCiència EnsenyamentCross-Sectional StudiesAttitudeSexual HarassmentSpainHarassmentFemalebusinessSocial psychologyTransphobia050104 developmental & child psychologyDemography
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Virtual reality versus computer-aided exposure treatments for fear of flying

2011

Evidence is growing that two modalities of computer-based exposure therapies—virtual reality and computer-aided psychotherapy—are effective in treating anxiety disorders, including fear of flying. However, they have not yet been directly compared. The aim of this study was to analyze the efficacy of three computer-based exposure treatments for fear of flying: virtual reality exposure therapy (VRET), computer-aided exposure with a therapist’s (CAE-T) assistance throughout exposure sessions, and self-administered computer-aided exposure (CAE-SA). A total of 60 participants with flying phobia were randomly assigned to VRET, CAE-T, or CAE-SA. Results indicate that the three interventions were …

AdultMaleAircraftPsychological interventionImplosive TherapyFlying PhobiaStatistics NonparametricVirtual realitylaw.inventionExposureFear of flyingVirtual Reality Exposure TherapyUser-Computer InterfaceArts and Humanities (miscellaneous)Randomized controlled trialFear of flyinglawDevelopmental and Educational PsychologymedicineHumansComputer SimulationAnalysis of VarianceIntention-to-treat analysisModalitiesfungiPor a volar--Tractament--Simulació per ordinadorFearMiddle Agedmedicine.diseaseFear of flying --Treatment--Computer simulationIntention to Treat AnalysisTreatmentClinical PsychologyTreatment OutcomePhobic DisordersComputer-aidedPatient SatisfactionRandomized controlled trialTherapy Computer-AssistedAnxietyFemalemedicine.symptomPsychologyClinical psychology
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Virtual reality treatment of flying phobia.

2002

Flying phobia (FP) might become a very incapacitating and disturbing problem in a person's social, working, and private areas. Psychological interventions based on exposure therapy have proved to be effective, but given the particular nature of this disorder they bear important limitations. Exposure therapy for FP might be excessively costly in terms of time, money, and efforts. Virtual reality (VR) overcomes these difficulties as different significant environments might be created, where the patient can interact with what he or she fears while in a totally safe and protected environment, the therapist's consulting room. This paper intends, on one hand, to show the different scenarios desig…

AdultMaleAircraftmedicine.medical_treatmentApplied psychologyExposure therapyPsychological interventionVirtual realitySensitivity and SpecificityFlying PhobiaUser-Computer InterfaceComputer GraphicsMedicineHumansPatient treatmentComputer SimulationElectrical and Electronic EngineeringSimulationTravelConsulting roomCognitive Behavioral Therapybusiness.industryReproducibility of ResultsGeneral MedicineFearComputer Science ApplicationsMultiple baseline designTreatment OutcomePhobic DisordersTherapy Computer-AssistedChronic DiseaseAerospace MedicinePanic DisorderFemaleUser interfaceDesensitization PsychologicbusinessBiotechnologyIEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society
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MicroRNA hsa-miR-4717-5p regulates RGS2 and may be a risk factor for anxiety-related traits

2015

Regulator of G-protein Signaling 2 (RGS2) is a key regulator of G-protein-coupled signaling pathways involved in fear and anxiety. Data from rodent models and genetic analysis of anxiety-related traits and disorders in humans suggest down-regulation of RGS2 expression to be a risk factor for anxiety. Here we investigated, whether genetic variation in microRNAs mediating posttranscriptional down-regulation of RGS2 may be a risk factor for anxiety as well. 75 microRNAs predicted to regulate RGS2 were identified by four bioinformatic algorithms and validated experimentally by luciferase reporter gene assays. Specificity was confirmed for six microRNAs (hsa-miR-1271-5p, hsa-miR-22-3p, hsa-miR-3…

AdultMaleCandidate geneSingle-nucleotide polymorphismMIR4717ComorbidityBiologyBioinformaticsPolymorphism Single NucleotideCellular and Molecular NeuroscienceGenes ReporterRisk FactorsmedicineHumansIKBKEGenetic Predisposition to DiseaseAllelepanic disorderLuciferases3' Untranslated RegionsAgoraphobiaAllelesGenetic Association StudiesGenetics (clinical)miRNAGeneticsPanic disorderassociationComputational BiologyReproducibility of Resultsmedicine.diseaseAnxiety DisordersMicroRNAsPsychiatry and Mental healthGene Expression RegulationCase-Control StudiesLinear ModelsAnxiety sensitivityAnxietyFemalemedicine.symptomgene regulationRGS ProteinsAgoraphobiaAmerican Journal of Medical Genetics Part B-neuropsychiatric Genetics
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Using Augmented Reality to Treat Phobias

2005

Virtual reality (VR) is useful for treating several psychological problems, including phobias such as fear of flying, agoraphobia, claustrophobia, and phobia to insects and small animals. We believe that augmented reality (AR) could also be used to treat some psychological disorders. AR and VR share some advantages over traditional treatments. However, AR gives a greater feeling of presence (the sensation of being there) and reality judgment (judging an experience as real) than VR because the environment and the elements the patient uses to interact with the application are real. Moreover, in AR users see their own hands, feet, and so on, whereas VR only simulates this experience. With thes…

AdultMaleComputer sciencemedia_common.quotation_subjectCockroachesVirtual realitycomputer.software_genreFear of flyingUser-Computer InterfaceSensationComputer GraphicsmedicineAnimalsHumansComputer Simulationmedia_commonPhobiasMultimediaSpidersModels Theoreticalmedicine.diseaseComputer Graphics and Computer-Aided DesignTreatment OutcomeMultimediaPhobic DisordersFeelingTherapy Computer-AssistedClaustrophobiaFemaleAugmented realityDesensitization PsychologiccomputerSoftwareCognitive psychologyAgoraphobiaIEEE Computer Graphics and Applications
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Long-term cost-effectiveness of cognitive behavioral therapy versus psychodynamic therapy in social anxiety disorder.

2015

Background To determine the cost-effectiveness of cognitive behavioral therapy (CBT) versus psychodynamic therapy (PDT) in the treatment of social anxiety disorder after a follow-up of 30 months from a societal perspective. Methods This analysis was conducted alongside the multicenter SOPHO-NET trial; adults with a primary diagnosis of social anxiety disorder received CBT (n = 209) or PDT (n = 207). Data on health care utilization and productivity loss were collected at baseline, after 6 months (posttreatment), and three further follow-ups to calculate direct and indirect costs. Anxiety-free days (AFDs) calculated based on remission and response were used as measure of effect. The increment…

AdultMaleCost effectivenessmedicine.medical_treatmentCost-Benefit AnalysisTime03 medical and health sciencesIndirect costs0302 clinical medicineWillingness to paymedicineHumanshealth care economics and organizationsPsychodynamic psychotherapyCost–benefit analysisCognitive Behavioral TherapySocial anxietyPhobia Social3. Good health030227 psychiatryCognitive behavioral therapyPsychiatry and Mental healthClinical PsychologyTreatment OutcomeCognitive therapyFemalePsychologyPsychotherapy Psychodynamic030217 neurology & neurosurgeryClinical psychologyDepression and anxiety
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Functional changes in brain activity after hypnosis in patients with dental phobia.

2015

Visiting the dentist is often accompanied by apprehension or anxiety. People, who suffer from specific dental phobia (a disproportional fear of dental) procedures show psychological and physiological symptoms which make dental treatments difficult or impossible. For such purposes, hypnosis is often used in dental practice as an alternative for a number of treatments adjuvant or instead of sedation or general anaesthetics, as medication is often associated with risks and side effects. This is the first study to address the effects of a brief dental hypnosis on the fear processing structures of the brain in dental phobics using functional magnetic resonance imaging (fMRI). 12 dental phobics (…

AdultMaleHypnosismedicine.medical_specialtyBrain activity and meditationAudiologyAmygdalaDental PhobiaYoung AdultPhysiology (medical)Dental AnxietymedicineHumansPsychiatryAnterior cingulate cortexmedicine.diagnostic_testGeneral NeuroscienceBrainMiddle AgedMagnetic Resonance Imagingmedicine.anatomical_structureTreatment OutcomeAnxietyFemalemedicine.symptomFunctional magnetic resonance imagingPsychologyInsulaHypnosisJournal of physiology, Paris
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Blood endocannabinoid levels in patients with panic disorder.

2020

Abstract Background The development and maintenance of anxiety disorders is not fully understood. There is consensus in the literature that in addition to genetic factors, social, psychological and neurobiological factors are of crucial importance. The present exploratory study investigates the influence of the endocannabinoids (EC) and related N-acylethanolamines (NA) on the maintenance of panic disorder (PD). Methods A total of n = 36 PD and n = 26 healthy controls (HC) were included in the study. Baseline characteristics showed no differences between the two groups. The participants were exposed to the Trier Social Stress Test (TSST) for reliable laboratory stress induction. Blood sample…

AdultMaleHypothalamo-Hypophyseal SystemHydrocortisoneEndocrinology Diabetes and MetabolismPhysiologyPituitary-Adrenal System03 medical and health sciences0302 clinical medicineEndocrinologyHeart RateTrier social stress testMedicineHumansSalivaBiological PsychiatryEndocrine and Autonomic Systemsbusiness.industryPanic disorderStressorRepeated measures designMiddle Agedmedicine.diseaseEndocannabinoid system030227 psychiatryPsychiatry and Mental healthEthanolaminesAnxietyPanic DisorderFemalemedicine.symptombusinessPsychosocial030217 neurology & neurosurgeryStress PsychologicalAgoraphobiaEndocannabinoidsPsychoneuroendocrinology
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