Search results for "Photic stimulation"
showing 10 items of 307 documents
COMT genotype predicts BOLD signal and noise characteristics in prefrontal circuits.
2006
Abstract Objective: Prefrontal dopamine (DA) is catabolized by the COMT (catechol- O -methyltransferase) enzyme. Literature suggests that the Val/Met single nucleotide polymorphism (SNP) in the COMT gene predicts executive cognition in humans with Val carriers showing poorer performance due to less available synaptic DA. Recent fMRI studies are thought to agree with these studies having demonstrated prefrontal hyperactivation during n -back and attention-requiring tasks. This was interpreted as “less efficient” processing due to impaired signal-to-noise ratio (SNR) of neuronal activity. However, electrophysiological studies of neuronal SNR in primates and humans imply that prefrontal cortex…
Encoding of faces and objects into visual working memory: an event-related brain potential study.
2013
Visual working memory (VWM) is an important prerequisite for cognitive functions, but little is known on whether the general perceptual processing advantage for faces also applies to VWM processes. The aim of the present study was (a) to test whether there is a general advantage for face stimuli in VWM and (b) to unravel whether this advantage is related to early sensory processing stages. To address these questions, we compared encoding of faces and complex nonfacial objects into VWM within a combined behavioral and event-related brain potential (ERP) study. In detail, we tested whether the N170 ERP component - which is associated with face-specific holistic processing - is affected by mem…
The preview benefit for familiar and unfamiliar faces
2013
Abstract Previewing distracters improves visual search – the preview benefit ( Watson & Humphreys, 1997 ). Recent fMRI evidence suggests that the preview benefit rests on active inhibition in brain regions concerned with spatial memory, as well as in content selective areas ( Allen, Humphreys, & Matthews, 2008 ). Using familiar and unfamiliar faces in a preview search task we show that search performance is much better with familiar than with unfamiliar faces. With both types of stimuli we obtained preview benefits of at least 10%, measured in terms of the advantage in reaction time relative to the no preview condition. The preview benefit increased up to 30% when distracter faces and their…
Excitability of subcortical motor circuits in Go/noGo and forced choice reaction time tasks
2006
The size of the response to a startling auditory stimulus (SAS) may reflect the excitability of the reticulospinal tract. In this study, we examined whether there was any excitability change in the reticulospinal tract during preparation for execution of two types of choice reaction time task: a forced choice reaction time task (fCRT) and a Go/no-Go task (GnG). In 13 healthy volunteers we used three types of trials: control trials in which subjects were requested to perform ballistic wrist movements during fCRT or GnG tasks; test trials in which a SAS was presented with the visual cue, and baseline trials in which SAS was presented alone. Latency and area of the responses to SAS were measur…
Color and time perception: Evidence for temporal overestimation of blue stimuli.
2017
The perceived duration of a visual stimulus depends on various features, such as its size, shape, and movement. Potential effects of stimulus color have not been investigated in sufficient detail yet, but the well-known effects of arousal on time perception suggest that arousing hues, such as red, might induce an overestimation of duration. By means of a two-interval duration discrimination task in the sub-second range, we investigated whether participants overestimate the duration of red stimuli in comparison to blue stimuli, while controlling for differences in brightness (individual adjustments by means of flicker photometry) and saturation (colorimetric adjustment in terms of the CIELAB…
Conflicts in language processing: A new perspective on the N400-P600 distinction
2011
Conflicts in language processing often correlate with late positive event-related brain potentials (ERPs), particularly when they are induced by inconsistencies between different information types (e.g. syntactic and thematic/plausibility information). However, under certain circumstances, similar sentence-level interpretation conflicts (inanimate subjects) engender negativity effects (N400s) instead. The present ERP study was designed to shed light on this inconsistency. In previous studies showing monophasic positivities (P600s), the conflict was irresolvable and induced via a verb. whereas N400s were elicited by resolvable, argument-induced conflicts. Here, we therefore examined irresolv…
Human eyes do not need monochromatic aberrations for dynamic accommodation
2017
Purpose To determine if human accommodation uses the eye's own monochromatic aberrations to track dynamic accommodative stimuli. Methods Wavefront aberrations were measured while subjects monocularly viewed a monochromatic Maltese cross moving sinusoidally around 2D of accommodative demand with 1D amplitude at 0.2 Hz. The amplitude and phase (delay) of the accommodation response were compared to the actual vergence of the stimulus to obtain gain and temporal phase, calculated from wavefront aberrations recorded over time during experimental trials. The tested conditions were as follows: Correction of all the subject's aberrations except defocus (C); Correction of all the subject's aberratio…
Visuospatial processing in schizophrenia: Does it share common mechanisms with pseudoneglect?
2011
International audience; ''Schizophrenia patients demonstrate behavioural and cerebral lateralised anomalies, prompting some authors to suggest they exhibit a mild form of right unilateral neglect. To better describe and understand lateralised visuospatial anomalies in schizophrenia, three experiments were run using tasks often utilised to study visuospatial processing in healthy individuals and in neglect patients: the Behavioural Inattention Test (BIT), the manual line bisection task with and without a local cueing paradigm, the landmark task (or line bisection judgement), and the number bisection task. Although the schizophrenia patients did not exhibit the full-blown neglect syndrome, th…
Effects of valence and arousal on implicit approach/ avoidance tendencies: A fMRI study.
2018
To date, it is still a matter of debate, whether valence or valence and arousal interactively foster implicit approach and avoidance tendencies, and which neural circuitries underlie these effects. To address these questions, we investigated the effects of valence and arousal on implicit approach/avoidance tendencies during fMRI in healthy volunteers (N=46). The implicit approach of positive social scenes was associated with shorter response preparation times and increased activation of the lingual, parahippocampal and fusiform gyri. Valence and arousal did not influence reaction times interactively, but we observed increased activation of prefrontal, motor, temporal, middle cingulate and p…
Parieto-frontal interactions in visual-object and visual-spatial working memory: Evidence from transcranial magnetic stimulation
2001
This study aimed to investigate whether transcranial magnetic stimulation (TMS) can induce selective working memory (WM) deficits of visual-object versus visual-spatial information in normal humans. Thirty-five healthy subjects performed two computerized visual n-back tasks, in which they were required to memorize spatial locations or abstract patterns. In a first series of experiments, unilateral or bilateral TMS was delivered on posterior parietal and middle temporal regions of both hemispheres after various delays during the WM task. Bilateral temporal TMS increased reaction times (RTs) in the visual-object, whereas bilateral parietal TMS selectively increased RTs in the visual-spatial W…