Search results for "Phylogenetic"

showing 10 items of 1179 documents

Sympathetic Overactivity and 24-Hour Blood Pressure Pattern in Hypertensives with Chronic Renal Failure

1995

In order to assess the activity of the sympathetic system and to evaluate the 24-h blood pressure pattern in hypertensives with chronic renal failure (CRF), 12 CRF patients and 16 essential hypertensives (EHs) were studied. In all subjects, plasma samples for catecholamines and renin activity were obtained both in the basal condition and after standing, and 24-h blood pressure monitoring (ABPM) was performed. The 24-h mean blood pressure results were quite similar between CRFs and EHs. In 50% of the CRFs, ABPM showed a nighttime decrease in diastolic BP (DBP) greater than 10%, while in the remaining 50% the ABPM indicated a nondipper blood pressure pattern. Of the 16 EHs, 4 had a nighttime …

medicine.medical_specialtySympathetic nervous systemSympathetic Nervous SystemEpinephrineDiastoleBlood PressureCritical Care and Intensive Care MedicinePlasma renin activityNorepinephrineBasal (phylogenetics)CatecholaminesInternal medicineBlood plasmaHumansMedicinebusiness.industryGeneral MedicineBlood Pressure Monitoring AmbulatoryCircadian RhythmMean blood pressureBlood pressuremedicine.anatomical_structureEndocrinologyNephrologyHypertensionCatecholamineKidney Failure Chronicbusinessmedicine.drugRenal Failure
researchProduct

Transient mid-ventricular dyskinesia: a variant of Takotsubo syndrome

2008

Takotsubo Cardiomyopathy is characterized by a reversible systolic left ventricular apical ballooning. A new pattern of dyskinesia in the absence of angiographic evidence of coronary artery stenosis has been indicated like a variant of takotsubo cardiomiopathy: mid-ventricular akinesis with preservation of apical and basal contractilities revealed at echocardiograms and ventriculographies. We report the case of a 65 years old patient with this pattern, reverted in 4 weeks.

medicine.medical_specialtyTakotsubo syndromeTakotsubo Cardiomyopathy Mid-ventricular dyskinesia Echocardiograms VentriculographiesHeart diseasebusiness.industryCardiomyopathyNeurological disordermedicine.diseaseVentricular dyskinesiaSurgeryCentral nervous system diseaseBasal (phylogenetics)DyskinesiaInternal medicinecardiovascular systemCardiologyMedicinecardiovascular diseasesmedicine.symptomCardiology and Cardiovascular Medicinebusiness
researchProduct

Do overactive bladder symptoms and their treatment-associated changes exhibit a normal distribution? Implications for analysis and reporting

2020

Aims: To explore the use of means vs medians (assuming or not the presence of normal distribution) in studies reporting overactive bladder syndrome symptoms and to test for normal distribution of basal values and treatment-associated changes thereof in two large noninterventional studies. Methods: Systematic review of all original studies reporting on at least one overactive bladder syndrome symptom published in four leading urology journals in 2016 to 2017. Testing of the normal distribution of urgency, incontinence, frequency, and nocturia in two large noninterventional studies (n = 1335 and 745). Results: Among 48 eligible articles, 86% reported means (assuming a normal distribution), 6%…

medicine.medical_specialtyUrologyMedizin030232 urology & nephrologyNormal Distribution610 MedizinNormal distribution03 medical and health sciencesBasal (phylogenetics)0302 clinical medicineInternal medicine610 Medical sciencesmedicineNocturiaHumansBaseline values030219 obstetrics & reproductive medicinebusiness.industryUrinary Bladder Overactivemedicine.diseaseOveractive bladder syndrome3. Good healthUrinary IncontinenceOveractive bladderPropiverineNocturiaNeurology (clinical)medicine.symptombusinessmedicine.drug
researchProduct

The Female Sex Confers Different Prognosis in Heart Failure: Same Mortality but More Readmissions

2021

Introduction: Heart failure (HF) is a major cause of morbimortality both in men and women. Differences between sex in etiopathogenesis, response to treatment, and quality of care have been found in patients with HF. Females are usually under-represented in clinical trials and there is no solid evidence demonstrating the influence of sex in the prognostic of chronic HF. The primary objective of this study was to analyse the differences in mortality and probability of hospital readmission between males and females with HF. The secondary objective was to compare mortality and probability of hospital readmission by ejection fraction (reduced vs. preserved).Methods: Patients with decompensated H…

medicine.medical_specialtylcsh:Diseases of the circulatory (Cardiovascular) systemMultivariate analysisheart failuremorbidity030204 cardiovascular system & hematologyCardiovascular Medicinereadmissions03 medical and health sciencesBasal (phylogenetics)0302 clinical medicineInternal medicinegenderMedicinesex030212 general & internal medicineOriginal ResearchHospital readmissionEjection fractionbusiness.industryFemale sexleft ventricular ejection fractionmedicine.diseaseResponse to treatmentmortalityClinical triallcsh:RC666-701Heart failureCardiologyCardiology and Cardiovascular MedicinebusinessFrontiers in Cardiovascular Medicine
researchProduct

Impasse in the management of recurrent basal cell carcinoma of the skull with sagittal sinus erosion

2015

Abstract Basal cell carcinoma (BCC) is a non melanocytic skin cancer that arises from basal cells, affecting commonly fair-skinned human beings. Although the tumor is well known for local recurrences, extension into the intracranial space is reported. A case of a giant BCC of the scalp invading the middle and posterior third of the superior sagittal sinus (SSS) is reported. A 70-year-old male with a basal cell carcinoma history presented with a massive bleeding from the SSS invaded by the tumor. Since the patient refused surgery the bleeding was managed through direct compression by applying a thrombin-based hemostatic agents and sterile dressings. This procedure was performed daily in orde…

medicine.medical_specialtylcsh:Surgerylcsh:RC346-429Basal (phylogenetics)MedicineBasal cell carcinomalcsh:Neurology. Diseases of the nervous systemmedicine.diagnostic_testintegumentary systembusiness.industryMagnetic resonance imaginglcsh:RD1-811medicine.diseaseSurgerySSS*Superior sagittal sinusSkullmedicine.anatomical_structureScalpBasal cell carcinomaConservative managementSurgeryNeurology (clinical)Skin cancerbusinessSuperior sagittal sinusInterdisciplinary Neurosurgery
researchProduct

The role of in situ species diversification for the evolution of high vascular plant species diversity in the European Alps—A review and interpretati…

2017

Abstract By harbouring ca. 3500 native vascular plant species in an area of ca. 170 000 km2, the European Alps represent a region of very high species diversity. Using the most recently published flora of the area and phylogenetic literature, I here review which proportion of the endemic flora of the Alps is the result of in situ diversification, i.e., of diversification in the area and (largely) restricted to the area. There exist only very few and mostly species-poor species diversifications in the Alps, accounting for ca. 1.2% of the native and for ca. 9% of the endemic flora of the Alps. In contrast to this, ca. 33% of the endemic species of the Alps belong to lineages widespread in the…

musculoskeletal diseases0106 biological sciences0301 basic medicineVascular plantFloraExtinctionFlora of the AlpsbiologyPhylogenetic treeEcologymusculoskeletal neural and ocular physiologySpecies diversityPlant Sciencemusculoskeletal systembiology.organism_classification010603 evolutionary biology01 natural sciences03 medical and health sciences030104 developmental biologystomatognathic systemEndemismQuaternaryEcology Evolution Behavior and SystematicsPerspectives in Plant Ecology, Evolution and Systematics
researchProduct

Hearing loss in facioscapulohumeral dystrophy.

1986

Bilateral sloping high frequency hearing loss of 20–90 dB was found in six out of ten patients with infantile or adolescent onset FSHD. In all cases the basic defect could be traced to the cochlea. The outer hair cells of the basal turn are predominantly affected. In 20 patients with various other forms of muscular dystrophy or neuromuscular disorders with an FSH distribution, no sensorineural hearing loss was found. Myopathology of FSHD patients extended from mild to severe, often showing inflammatory infiltrates and type I fibre atrophy, without unequivocal differences between the two groups with and without hearing loss. It is concluded that cochlear dysfunction is a specific and frequen…

musculoskeletal diseasesmedicine.medical_specialtyShoulderAdolescentHearing lossBiopsyFacial MusclesAudiologyMuscular DystrophiesBasal (phylogenetics)Atrophyotorhinolaryngologic diseasesMedicineHumansMuscular dystrophyChildHearing LossHearing Loss High-FrequencyCochleaEarly onsetRetrospective Studiesbusiness.industryHearing TestsMusclesDystrophySyndromemedicine.diseaseMuscular AtrophyPediatrics Perinatology and Child HealthSensorineural hearing lossmedicine.symptombusinessEuropean journal of pediatrics
researchProduct

The late Late Albian (Mortoniceras fallax Zone) cephalopod fauna from the Bracquegnies formation at Strépy-Thieu (Hainaut, southern Belgium).

2016

Excavations in 1989-1990 for the construction of a boat lift near the villages of Strépy and Thieu, east of Mons (province of Hainaut, southern Belgium), exposed a 40-metre section of the Bracquegnies Formation (Haine Green Sandstone Group; the ‘Meule de Bracquegnies’ of previous authors). Several hundred well-preserved, silicified cephalopods were collected from between 15 and 35 metres above the base of the sequence temporarily exposed there. The fauna is: Eutrephoceras clementianum (d’Orbigny, 1840), Puzosia (Puzosia) mayoriana (d’Orbigny, 1841), Callihoplites tetragonus (Seeley, 1865), Discohoplites valbonnensis valbonnensis (Hébert & Munier-Chalmas, 1875), Cantabrigites cantabrigense S…

nautiloidstaxonomyAmmonitesAmmonoidea[SDV.BID.SPT] Life Sciences [q-bio]/Biodiversity/Systematics Phylogenetics and taxonomyNautiloidea[SDU.STU.PG] Sciences of the Universe [physics]/Earth Sciences/PaleontologyAlbiantaxonomy.Cretaceous[ SDV.BID.SPT ] Life Sciences [q-bio]/Biodiversity/Systematics Phylogenetics and taxonomy[ SDU.STU.PG ] Sciences of the Universe [physics]/Earth Sciences/Paleontology
researchProduct

Description and phylogenetic relationships of a new species of treefrog of theOsteocephalus buckleyispecies group (Anura: Hylidae)

2020

The Osteocephalus buckleyi species group is widely distributed in primary and secondary forests of the Amazon Basin and Guiana Region. Based on integrative analysis, including morphological and genetic data, we estimate the phylogenetic relationships and species boundaries among populations of the Osteocephalus buckleyi group from the Ecuadorian Amazon, focusing on the O. verruciger-O. cannatellai species complex. Our results uncovered the existence of one confirmed candidate species from Sangay National Park and one unconfirmed candidate species. Here, we describe the new species which is morphologically and ecologically distinct from other Osteocephalus species. The new species is unusual…

new species0106 biological sciencesecuadorGlobal and Planetary ChangeOsteocephalusEcologyPhylogenetic treeosteocephalus010607 zoologyBiodiversityGeneral. Including nature conservation geographical distributionZoologyQH1-199.5Biologymolecular toolsbiology.organism_classification010603 evolutionary biology01 natural sciencesHylidaeSpecies groupQH540-549.5Ecology Evolution Behavior and SystematicsbiodiversityAmazon basinNeotropical Biodiversity
researchProduct

Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella

2017

The α-proteobacterial genus Bartonella comprises a group of ubiquitous mammalian pathogens that are studied as a model for the evolution of bacterial pathogenesis. Vast abundance of two particular phylogenetic lineages of Bartonella had been linked to enhanced host adaptability enabled by lineage-specific acquisition of a VirB/D4 type IV secretion system (T4SS) and parallel evolution of complex effector repertoires. However, the limited availability of genome sequences from one of those lineages as well as other, remote branches of Bartonella has so far hampered comprehensive understanding of how the VirB/D4 T4SS and its effectors called Beps have shaped Bartonella evolution. Here, we repor…

parallel evolution0301 basic medicineBartonellaAMPylation; bacterial effector; filamentation induced by cAMP; parallel evolutionVirulence FactorsIn silico030106 microbiologyBiologyfilamentation induced by cAMPGenomeEvolution MolecularType IV Secretion Systems03 medical and health sciencesBacterial ProteinsBartonella InfectionsGeneticsAMPylationHumansEvolutionary dynamicsBacterial Secretion SystemsPhylogenyEcology Evolution Behavior and SystematicsPhylogenetic treeEffectorbiology.organism_classificationbacterial effectorVirology030104 developmental biologyEvolutionary biologyFilamentation induced by cAMP; AMPylation; Parallel evolution; Bacterial effectorHost-Pathogen InteractionsParallel evolutionAdaptationBartonellaResearch Article
researchProduct