Search results for "Physical exercise"

Molecular hydrogen (H 2 ) as a potential treatment for acute and chronic fatigue

2020

Many diseases as well as acute conditions can lead to fatigue, which can be either temporary or chronic in nature. Acute fatigue develops frequently after physical exercise or after alcohol hangover, whereas microbial infections such as influenza or COVID-19 and chronic diseases like Parkinson's disease or multiple sclerosis are often associated with chronic fatigue. Oxidative stress and a resulting disturbance of mitochondrial function are likely to be common denominators for many forms of fatigue, and antioxidant treatments have been shown to be effective in alleviating the symptoms of fatigue. In this study, we review the role of reactive oxygen and nitrogen species in fatigue and the an…

Antioxidants in skeletal muscle physiology, a radically different approach.

2015

Regular physical exercise has many health benefits (1). Paradoxically, it is also clear that contracting skeletal muscles generate reactive oxygen species (ROS) and that prolonged and intense exercise can result in oxidative damage to cellular constituents (2-4). Reactive oxygen species production is dependent on the intensity of the exercise with higher amount of ROS generated by strenuous exercise (5, 6). Antioxidants may reduce the adverse effects of exercise-induced ROS (2-4). However, ROS are not only toxic but rather play an important role in cell signalling and in the regulation of gene expression (7, 8) and force production in skeletal muscle (9). Thus, we have recently raised quest…

Exercise as an antioxidant: it up-regulates important enzymes for cell adaptations to exercise

2006

Abstract Aims. – To assess the role of the reactive oxygen species (ROS) in cell signalling and in the regulation of gene expression. Methods. – Exercise causes oxidative stress only when exhaustive. Strenuous exercise causes oxidation of glutathione, release of cytosolic enzymes, and other signs of cell damage. We have tested this hypothesis by studying the effect of inhibition of ROS production by allopurinol (an inhibitor of xanthine oxidase, a free radical generating enzyme) on cell signalling pathways in marathon runners and in rats submitted to exhaustive exercise by running on a treadmill. Results. – Exercise caused an activation of NF-κB in lymphocytes from marathon runners which wa…

COGNITION AND PHYSICAL ACTIVITY ACROSS AGES

2021

Physical activity and exercise in mild cognitive impairment and dementia::an umbrella review of intervention and observational studies

2020

Objectives:\ud \ud The aim of this umbrella review was to determine the effect of physical activity/exercise on improving cognitive and noncognitive outcomes in people with MCI (mild cognitive impairment) and dementia.\ud \ud Design:\ud \ud Umbrella review of systematic reviews (SR), with or without meta-analyses (MAs), of randomized controlled trials (RCTs) and observational studies.\ud \ud Settings and Participants:\ud \ud People with MCI or dementia, confirmed through validated assessment measures. Any form of physical activity/exercise was included. As controls, we included participants not following any prespecified physical activity/exercise intervention or following the same standard…

A single bout of physical exercise does not affect young adults’ executive functions

2020

Summary Study aim. The purpose of the current study is to determine the impact of single bouts of physical exercise of different duration and intensity on young adults’ executive functions. Material and methods. The study employed 81 participants (37 females, 44 males) ranging between 19 and 39 years (mean age: 24.6 ± 4.08 years; mean height: 168 ± 9.67 cm; mean weight: 67.2 ± 13.0 kg). The executive functions were assessed through the Stroop task, the Tower of London test, and the Corsi block test. Participants were randomly assigned to one of the three experimental conditions (30-second Wingate test condition, an incremental intensity exercise test, and a submaximal constant-intensity tes…

The Impact of the Progressive Efficiency Test on a Rowing Ergometer on White Blood Cells Distribution and Clinical Chemistry Changes in Paralympic Ro…

2017

Abstract There is a large gap in knowledge regarding research on post-exercise blood changes in disabled athletes. There are relatively few data on adaptive mechanisms to exercise in disabled athletes, including disabled rowers. Two rowers from a Polish adaptive rowing settle TAMix2x that qualified for the Paralympic Games in Rio, 2016 took part in this study. They performed a progressive test on a rowing ergometer until exhaustion. The cardiorespiratory fitness measures, complete blood count, white blood cells’ distribution and 30 clinical chemistry variables describing laboratory diagnostic profiles and general health were determined. The extreme effort induced changes in all studied meta…

Function and Fiber-Type Specific Distribution of Hsp60 and αB-Crystallin in Skeletal Muscles: Role of Physical Exercise

2021

Simple Summary Skeletal muscle represents about 40% of the body mass in humans and it is a copious and plastic tissue, rich in proteins that are subject to continuous rearrangements. Physical exercise is considered a physiological stressor for different organs, in particular for skeletal muscle, and it is a factor able to stimulate the cellular remodeling processes related to the phenomenon of adaptation. All cells respond to various stress conditions by up-regulating the expression and/or activation of a group of proteins called heat shock proteins (HSPs). Although their expression is induced by several stimuli, they are commonly recognized as HSPs due to the first experiments showing thei…

Comparison of the roles of common constitutional and behavioural parameters in back performance estimates

2006

Objective: To compare the associations between different physical activity histories and anthropometric measures in isokinetic lifting performance, isometric back extension endurance and psychophysical lifting tests. Background: The relative roles and interaction of these factors related to back function are largely unknown. Methods: The subjects consisted of a population-based sample of 210 working-age males. Paraspinal muscle cross-sectional areas were obtained by magnetic resonance imaging; anthropometric measures, isokinetic and psychophysical lifting capacity, and isometric back extension endurance tests were performed and current and physical activity histories and occupational loadin…

Do E-Athletes Move?

2016

This article offers possibly the first peer-reviewed study on the training routines of elite e-athletes with special focus on the subjects' physical exercise routines. The study is based on a sample of 115 elite e-athletes. According to the responses, e-athletes train approximately 5.28 hours every day around the year on the elite level. Approximately 1.08 hours of that training is physical exercise. More than half (55.6%) of the elite e-athletes believe that integrating physical exercise in their training programs has a positive effect on esport performance; however, no less than 47.0% of the elite e-athletes do their physical exercise chiefly to maintain overall health. Accordingly, the s…