Search results for "Physicochemical propertie"

showing 10 items of 22 documents

Systematic study of the physicochemical properties of a homologous series of aminobisphosphonates

2012

ABSTRACT: Aminobisphosphonates, e.g., alendronate and neridronate, are a well known class of molecules used as drugs for various bone diseases. Although these molecules have been available for decades, a detailed understanding of their most important physicochemical properties under comparable conditions is lacking. In this study, ten aminobisphosphonates, H2N(CH2)nC(OH)[P(O)(OH)2]2, in which n = 2-5, 7-11 and 15 have been synthesized. Their aqueous solubility as a function of temperature and pH, pKa-values, thermal stability, IR absorptions, and NMR spectral data for both liquid (1H, 13C, 31P-NMR) and solid state (13C, 15N and 31P-CPMAS NMR) were determined. Peer reviewed

Magnetic Resonance Spectroscopy116 Chemical sciencesSolid-statePharmaceutical Sciencephysicochemical properties010402 general chemistry01 natural sciencesArticleAnalytical Chemistrylcsh:QD241-441Homologous serieschemistry.chemical_compoundlcsh:Organic chemistryComputational chemistrybisphosphonates; aqueous solubility; pKa; physicochemical propertiesaqueous solubilityDrug DiscoveryAqueous solubilityMoleculeOrganic chemistrypKaThermal stabilityPhysical and Theoretical ChemistrySolubilitySpectral datata116bisphosphonatesAlendronateDiphosphonates010405 organic chemistryChemistryOrganic ChemistryTemperaturebisphosphonates aqueous solubility pKa physicochemical propertiesWaterNuclear magnetic resonance spectroscopyHydrogen-Ion Concentration0104 chemical sciences3. Good healthSolubilityChemistry (miscellaneous)Molecular Medicine
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Structure and thermal properties of a chitosan coated polyethylene bilayer film

2012

The thermal and the structural properties of chitosan coated polyethylene (PE) films were studied. The coating process did not significantly influence the thermal stability and the PE surface structure and/or composition of the polyolefin. Dehydration temperature of chitosan films reflected the strength of water/acetic acid/chitosan chains interactions. Glycerol, used as a plasticizer, formed new hydrophilic centres in the film matrix. Moreover it was better integrated in the CSEGLY than in CSAGLY network. Besides, the addition of a plasticizer in the chitosan films decreased the film degradation temperature. There were two main steps for the PE chitosan coated films degradation. The first …

Materials sciencePolymers and Plastics[SDV]Life Sciences [q-bio]BIOPOLYMERmacromolecular substances02 engineering and technologyengineering.material010402 general chemistryBLENDS01 natural sciencesChitosanchemistry.chemical_compoundAcetic acidCoatingPLASTIC FILMSPolymer chemistryMolecular interactionsMaterials ChemistryOXYGEN BARRIER[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyThermal stabilityPERMEABILITYTEMPERATUREMicrostructureEDIBLE FILMSBilayertechnology industry and agriculturePlasticizerThermal stabilityDEGRADATIONPolyethyleneChitosan coatingequipment and supplies021001 nanoscience & nanotechnologyCondensed Matter Physicspolyethylene; chitosan coating; thermal stability; microstructure; molecular interactions0104 chemical sciencesPolyolefincarbohydrates (lipids)chemistryChemical engineeringPolyethyleneMechanics of MaterialsPHYSICOCHEMICAL PROPERTIES[SDE]Environmental Sciencesengineering0210 nano-technologyBEHAVIORPolymer Degradation and Stability
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Carbon nanotube – Protamine hybrid: Evaluation of DNA cell penetration

2016

International audience; Carbon nanotubes (CNTs) represent a class of nanomaterials with important potential for biomedical and biotechnological applications. CNT based vectorization is an emerging approach to the transport of nucleic acid through cell membrane but limited by detachment of DNA and degradation process. To increase DNA internalization, it was proved that cationic functionalized CNT was essential. In such a way, protamine efficiently used in several transfection processes is a cationic protein which was never associated to CNT.We propose here a novel nanovector based on single-walled carbon nanotubes (SWCNT) functionalized by protamine. Our results based on qPCR methods clearly…

Materials sciencemedia_common.quotation_subjectmammalian-cellsCarbon nanotubesnoncovalent sidewall-functionalizationProtamineNanotechnology02 engineering and technologyCarbon nanotubetransportersphysicochemical propertiesin-vitro010402 general chemistryEndocytosis01 natural sciences[ CHIM ] Chemical Scienceslaw.inventionnonviral gene deliveryCell membranechemistry.chemical_compoundlawCellular internalizationmedicineendocytosis[CHIM]Chemical SciencesGeneral Materials ScienceInternalizationFunctionalizationComputingMilieux_MISCELLANEOUSmedia_commonbiologyMolecular dynamic simulationGeneral ChemistryTransfection[CHIM.MATE]Chemical Sciences/Material chemistry021001 nanoscience & nanotechnologyProtamineproteins0104 chemical sciencesdrug-deliverymedicine.anatomical_structureplasmid dnachemistryBiophysicsNucleic acidbiology.protein0210 nano-technologyNanovectorizationDNA
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Effect of refrigerated storage on microbiological, chemical and sensory characteristics of a ewes’ raw milk stretched cheese

2017

This study aimed to describe the effects of refrigerated storage up to 180 days on microbiological, chemical, physical, and sensory characteristics of a PDO ewes’ raw milk stretched cheese. To this aim, a total of 224 cheeses were manufactured in four consecutive production weeks, and series of 32 of them were examined before packaging and after 15, 30, 60, 90, 120, and 180 d of storage at 4 ± 2 °C in the dark, respectively. Lactic acid bacteria cocci displayed the highest levels (7.8 Log CFU*g−1) during early storage and decreased progressively over time (7.4 Log CFU*g−1), while the opposite trend was observed for lactic acid bacteria rods (from 6.5 to 7.3 Log CFU*g−1). TMC and enterocci s…

Microbiology (medical)Settore AGR/19 - Zootecnica SpecialePolymers and PlasticsFresh cheese; Physicochemical properties; Sensory analysis; Shelf-life; Storage; Food Science; Biomaterials; Safety Risk Reliability and Quality; Polymers and Plastics; Microbiology (medical)Sensory analysiStoragePhysicochemical propertieBiomaterialschemistry.chemical_compound0404 agricultural biotechnologyBrowningSettore AGR/18 - Nutrizione E Alimentazione AnimaleFood scienceSolubilitySafety Risk Reliability and QualityPolymers and PlasticbiologyShelf-life0402 animal and dairy science04 agricultural and veterinary sciencesRaw milkbiology.organism_classification040401 food science040201 dairy & animal scienceBiomaterialLactic acidchemistryOdorFatty acid compositionFresh cheeseBacteriaFood ScienceSettore AGR/16 - Microbiologia Agraria
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Effect of grape pomace from red cultivar 'Nero d’Avola' on the microbiological, physicochemical, phenolic profile and sensory aspects of ovine Vasted…

2022

Abstract Aims The purpose of this study was to functionalize an ovine stretched cheese belonging to 'Vastedda' typology with red grape pomace powder (GPP) of Nero d’Avola cultivar and to characterize the microbiological, physicochemical, phenolic profile and sensory characteristics of the final cheeses. Methods and Results Before cheeses production, GPP was characterized for its microbiological profile, antibacterial activity and polyphenolic content. No colonies of bacteria and yeasts were detected in the GPP. GPP showed a large inhibition spectrum against spoilage and pathogenic bacteria. Three classes of polyphenolic compounds belonging to flavan-3-ols, flavonol and phenolic acids were i…

Settore AGR/13 - Chimica AgrariaFood spoilagePasteurizationApplied Microbiology and Biotechnologylaw.inventionSettore AGR/17 - Zootecnica Generale E Miglioramento GeneticoNutraceuticalStarterCheeselawAnimalsVitisFood scienceCultivarpolyphenolic profileSheep DomesticWinemakingphysicochemical propertieSheepChemistryPomacePolyphenolsfood and beveragesGeneral MedicineMilkovine stretched cheesefunctional dairy productFood Microbiologygrape pomace powderFemaleFermentationcommercial starter cultureSettore AGR/16 - Microbiologia AgrariaBiotechnologyJournal of Applied Microbiology
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Evolution of indigenous starter microorganisms and physicochemical parameters in spontaneously fermented beef, horse, wild boar and pork salamis prod…

2020

Abstract The present work was carried out to evaluate the microbiological and physicochemical composition of salamis produced with the meat of beef, horse, wild boar and pork. Salami productions occurred under controlled laboratory conditions to exclude butchery environmental contaminations, without the addition of nitrate and nitrite. All trials were monitored during the ripening (13 °C and 90% relative humidity) extended until 45 d. The evolution of physicochemical parameters showed that beef and pork salamis were characterized by a higher content of branched chain fatty acids (FA) and rumenic acid than horse and wild boar salamis, whereas the last two productions showed higher values of …

Settore AGR/19 - Zootecnica SpecialeSwinePhysicochemical propertiesStaphylococcusSus scrofaBiologyCarnobacteriumMicrobiologyPhysicochemical propertie03 medical and health scienceschemistry.chemical_compoundStarterLipid oxidationLactobacillalesLactobacillusLactic acid bacteriaAnimalsHorsesFood scienceNitriteFatty acidsSpontaneously fermented meat030304 developmental biologyStaphylococci0303 health sciences030306 microbiologyRumenic acidfood and beveragesAcinetobacterbiology.organism_classificationFatty acidMeat ProductsRed MeatSettore AGR/15 - SCIENZE E TECNOLOGIE ALIMENTARIchemistryFermentationMiSeq IlluminaFood MicrobiologyCattleFermentationFermented FoodsFood ScienceSettore AGR/16 - Microbiologia Agraria
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Influence of Citrus Essential Oils on the Microbiological, Physicochemical and Antioxidant Properties of Primosale Cheese

2022

The aim of this study was to produce a fresh ovine pressed cheese within Pecorino “Primosale” typology with the addition of citrus essential oils (EOs). For this purpose, ewe’s pasteurized milk was added with EOs from the peel of lemons, oranges and tangerines. Seven cheese productions were performed at the pilot plant scale level, including one control production (CP) without the addition of EOs and six experimental productions obtained by the addition of two EO concentrations (100 and 200 µL/L) to milk. The acidification process was obtained by means of the starter cultures Lactococcus lactis CAG4 and PON36. All cheeses showed levels of lactic acid bacteria (LAB) a…

Settore AGR/19 - Zootecnica Specialeovine cheese; citrus essential oils; <i>Lactococcus lactis</i>; physicochemical properties; volatile organic compounds; antioxidant capacityPhysiologySettore AGR/13 - Chimica AgrariaClinical BiochemistryCell BiologyMolecular BiologyBiochemistryantioxidant capacity citrus essential oils Lactococcus lactis ovine cheese physicochemical properties volatile organic compoundsSettore AGR/16 - Microbiologia AgrariaAntioxidants
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Steviol glycosides and bioactive compounds of a beverage with exotic fruits and Stevia rebaudiana Bert. as affected by thermal treatment

2020

The aim of this study was to investigate the effects of thermal processing on physicochemical properties, steviol glycosides, bioactive compounds, and antioxidant capacity degradation of a beverage based on exotic fruit juices, orange juice, açaí, and oat and sweetened with Stevia rebaudiana water extracts at different concentrations. The experimental design comprised a response surface methodology according to a central composite face-centered design. The variable ranges were 60–99°C, 0.25–15 min, 0–2.5% Stevia percentage. This design was used to determine the optimal thermal processing-Stevia concentration in order to obtain the best retention of bioactive compounds and physicochemical pr…

Steviollcsh:TX341-641Thermal treatmentphysicochemical properties01 natural scienceschemistry.chemical_compound0404 agricultural biotechnologyFood sciencethermal processingsteviol glycosideschemistry.chemical_classificationbioactive compoundslcsh:TP368-456stevia rebaudiana bertoni010401 analytical chemistryGlycoside04 agricultural and veterinary sciences040401 food science0104 chemical sciencesStevia rebaudianaAntioxidant capacitylcsh:Food processing and manufacturechemistrytotal antioxidant capacityexotic fruitslcsh:Nutrition. Foods and food supplyFood ScienceInternational Journal of Food Properties
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Properties of titanium dioxide

2021

"Properties of titanium dioxide" presents a survey of the main physicochemical properties of TiO2 upon which rely all of the applications of this material. Structures and morphologies of titanium dioxide have been taken into account, also in correlation with thermodynamic properties. Bulk and surface defectivity has been described in detail, because of its relevant consequences in terms of catalytic activity. The basic mechanisms of interaction between photons and TiO2 have been discussed on the basis of the optoelectronic features of the semiconductor. Finally, electrical, mechanical, and rheological properties of TiO2 have been presented.

Titanium dioxide Physicochemical properties Photocatalytic activity. Optoelectronic propertieschemistry.chemical_compoundMaterials scienceSemiconductorchemistrybusiness.industryTitanium dioxideNanotechnologyChemical stabilityBiocompatible materialbusiness
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Identification of Abies sibirica L. Polyprenols and Characterisation of Polyprenol-Containing Liposomes

2020

The needles of conifer trees are one of the richest sources of natural polyprenols. Polyprenol homologs from Abies sibirica L. lipophilic 80% purified extract were analyzed and quantified. In total, 10 peaks (Prenol-11 to Prenol-20) were observed in the ultra-high-performance liquid chromatography&ndash

food.ingredientPharmaceutical ScienceEthanol Injectionphysicochemical properties<i>Abies sibirica</i> L.High-performance liquid chromatographyLecithinAnalytical Chemistrylcsh:QD241-44103 medical and health sciencesPolyprenolchemistry.chemical_compound0302 clinical medicinefoodlcsh:Organic chemistryDrug DiscoverypolyprenolsPhysical and Theoretical ChemistrySolubility030304 developmental biology0303 health sciencesLiposomeChromatographybiologyOrganic ChemistryAbies sibiricabiology.organism_classificationchemistryChemistry (miscellaneous)030220 oncology & carcinogenesisYield (chemistry)liposomeMolecular MedicineHPLCMolecules
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