Search results for "Phytochemicals"

showing 10 items of 124 documents

The problem of misidentification between edible and poisonous wild plants: Reports from the Mediterranean area

2018

Abstract Today, in many European countries, people are looking for wild edible plants to experience new tastes and flavors, by following the new trend of being green and environmentally friendly. Young borage and spinach leaves can be easily confused by inexpert pickers with those of other plants, including poisonous ones, such as Mandragora autumnalis Bertol. (mandrake) or Digitalis purpurea L. (foxglove), common in southern and northern Italy respectively. In the last twenty years, several cases of intoxication by accidental ingestion of mandrake and foxglove have been reported. The purpose of this work was to perform a pharmacognostic characterization of young leaves from borage, mandrak…

0106 biological sciences0301 basic medicineChromatography GasDigitalis GlycosidePhytochemicalsIntoxicationBiologyPhytochemicalToxicology010603 evolutionary biology01 natural sciencesEdible plantGas Chromatography-Mass SpectrometryAccidental ingestion03 medical and health sciencesPlant leaveAlkaloidsAlkaloidHumansDiscriminant analysePoisonous plants Edible plants Plant leaves Accidental ingestion Intoxication Discriminant analysesBorageTraditional medicineMediterranean RegionSettore BIO/02 - Botanica SistematicaDigitalis purpureafood and beveragesMandragora autumnalisDigitalis GlycosidesDiscriminant analysesGeneral MedicineMandrakebiology.organism_classificationPoisonous plantPlant LeavesPlants Toxic030104 developmental biologyPhytochemicalItalyChromatography GaPoisonous plantsSettore BIO/03 - Botanica Ambientale E ApplicataAccidental ingestionEdible plantsEdible plantsMediterranean areaPlants EdibleFood ScienceHuman
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Phytochemical profiles, phototoxic and antioxidant properties of eleven Hypericum species - A comparative study

2018

Hypericum is one out of the nine genera belonging to the botanical family Clusiaceae Lindl (syn. Hypericaceae Juss.; APG III, 2009). The genus contains 484 species spread worldwide, one of which, Hypericum perforatum, is largely used in folk medicine. The aim of this study was to evaluate the chemical composition, along with the antioxidant and phototoxic activity, of 11 Hypericum species grown in Sicily (H. perforatum L., H. aegypticum L., H. androsaemum L., H. calycinum L., H. hircinum L., H. hirsutum L., H. montanum L., H. patulum Thunb., H. perfoliatum L., H. pubescens Boiss., H. tetrapterum Fr.). Samples of flowering tops collected from these Hypericum species were extracted and analys…

0106 biological sciencesDPPHHyperforinAntioxidants Hyperforin Hypericin Hypericum species (Clusiaceae Lindl.) Phototoxicity; PolyphenolsPhytochemicalsHypericinFlowersPlant ScienceHorticultureHypericaceae01 natural sciencesBiochemistryAntioxidantsMass SpectrometryPhototoxicityMicechemistry.chemical_compoundPicratesSpecies SpecificityHypericum species (Clusiaceae Lindl.) Phototoxicity Polyphenols Hypericin Hyperforin AntioxidantsAnimalsHypericum species (Clusiaceae Lindl.)Molecular BiologyChromatography High Pressure LiquidbiologyTraditional medicine010405 organic chemistryChemistryBiphenyl CompoundsPolyphenolsHypericum perforatumGeneral MedicineFibroblastsbiology.organism_classificationSettore AGR/02 - Agronomia E Coltivazioni Erbacee0104 chemical sciencesHypericinHyperforinPhotochemotherapyPhytochemicalPolyphenolNIH 3T3 CellsAntioxidantReactive Oxygen SpeciesHypericumHypericumDermatitis Phototoxic010606 plant biology & botany
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The Application of a Plant Biostimulant Based on Seaweed and Yeast Extract Improved Tomato Fruit Development and Quality

2020

Plant biostimulants are under investigation as innovative products to improve plant production and fruit quality, without resulting in environmental and food contaminations. Here, the effects of the application of Expando, a biostimulant based on seaweed and yeast extracts, on plant productivity, fruit ripening times, and fruit quality of Solanum lycopersicum var. Micro-Tom were evaluated. After biostimulant treatment, a two-week reduction of ripening times and a concomitant enhancement of the production percentage during the earliest ripening times, in terms of both fruit yield (+110%) and size (+85%), were observed. Concerning fruit quality, proximate analysis showed that tomatoes treated…

0106 biological sciencesDPPHPhytochemicalslcsh:QR1-50201 natural sciencesBiochemistryripening timeAntioxidantslcsh:Microbiologychemistry.chemical_compoundSolanum lycopersicumSettore BIO/10 - BiochimicaYeastsSettore BIO/04 - Fisiologia Vegetale0303 health sciencesMineralsABTSbiologyChemistry<i>Solanum lycopersicum</i>carotenoidsfood and beveragesRipeningfruit sizeBioactive compoundLycopeneHorticulturetocopherolsmineral contentArticle03 medical and health sciencesNutraceuticalPicratesYeast extractBenzothiazolesMolecular Biologypolyphenols030304 developmental biologySolanum lycopersicum; carotenoids; fruit quality; fruit size; lycopene; mineral content; polyphenols; ripening time; tocopherolsBiphenyl Compoundsfungifruit qualitybiology.organism_classificationSeaweedlycopeneFruitCarotenoids Fruit quality Lycopene Mineral content Polyphenols Ripening time Solanum lycopersicum TocopherolsSolanumSulfonic Acids010606 plant biology & botany
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Anthocyanins: Biosynthesis, Distribution, Ecological Role, and Use of Biostimulants to Increase Their Content in Plant Foods—A Review

2021

In the past century, plant biostimulants have been increasingly used in agriculture as innovative and sustainable practice. Plant biostimulants have been mainly investigated as potential agents able to mitigate abiotic stress. However, few information is available about their ability to influence fruit quality or change fruit phytochemical composition. In particular, very little is known about their effects on anthocyanin synthesis and accumulation. Due to the increasing demand of consumers for healthier foods with high nutraceutical values, this review tries to fill the gap between anthocyanin content and biostimulant application. Here, we elucidate the chemical structure, biosynthetic pat…

0106 biological sciencesDistribution (economics)antioxidant activityPlant ScienceBiologyPlant foods01 natural sciences03 medical and health scienceschemistry.chemical_compoundNutraceuticalBibliometric analysisSettore BIO/10 - BiochimicaSustainable agricultureSustainable practiceslcsh:Agriculture (General)030304 developmental biologynutraceuticals0303 health sciencesAbiotic stressbusiness.industryfungifruit qualityfood and beveragesphytochemicalslcsh:S1-972Biotechnologysustainable agricultureMeta-analysischemistryAgricultureAnthocyaninbusinessAnthocyanidins; Antioxidant activity; Bibliometric analysis; Fruit quality; Meta-analysis; Nutraceuticals; Phytochemicals; Sustainable agricultureAgronomy and Crop Scienceanthocyanidins010606 plant biology & botanyFood ScienceAgriculture
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Essential Oils Extracted from Different Species of the Lamiaceae Plant Family as Prospective Bioagents against Several Detrimental Pests

2020

On the basis of the side effects of detrimental synthetic chemicals, introducing healthy, available, and effective bioagents for pest management is critical. Due to this circumstance, several studies have been conducted that evaluate the pesticidal potency of plant-derived essential oils. This review presents the pesticidal efficiency of essential oils isolated from different genera of the Lamiaceae family including Agastache Gronovius, Hyptis Jacquin, Lavandula L., Lepechinia Willdenow, Mentha L., Melissa L., Ocimum L., Origanum L., Perilla L., Perovskia Kar., Phlomis L., Rosmarinus L., Salvia L., Satureja L., Teucrium L., Thymus L., Zataria Boissier, and Zhumeria Rech. Along with acute to…

0106 biological sciencesfood.ingredientHyptisLavandulaPhytochemicalsPharmaceutical ScienceReviewacute toxicitysublethal effectsSatureja01 natural sciencesRosmarinusessential oilAnalytical Chemistrylaw.inventionTeucriumlcsh:QD241-441foodlcsh:Organic chemistrylawDrug DiscoveryOils Volatilesublethal effectPesticidesPhysical and Theoretical ChemistrymonoterpenoidsEssential oilLamiaceaeMolecular StructurebiologyTraditional medicineOrganic ChemistryOriganumbiology.organism_classification010602 entomologyChemistry (miscellaneous)Insect RepellentsSettore BIO/03 - Botanica Ambientale E ApplicataMolecular MedicineLamiaceae010606 plant biology & botanyMolecules
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Indicaxanthin from Opuntia Ficus Indica (L. Mill) impairs melanoma cell proliferation, invasiveness, and tumor progression.

2018

Abstract Background: A strong, reciprocal crosstalk between inflammation and melanoma has rigorously been demonstrated in recent years, showing how crucial is a pro-inflammatory microenvironment to drive therapy resistance and metastasis. Purpose: We investigated on the effects of Indicaxanthin, a novel, anti-inflammatory and bioavailable phytochemical from Opuntia Ficus Indica fruits, against human melanoma both in vitro and in vivo. Study Design and Methods: The effects of indicaxanthin were evaluated against the proliferation of A375 human melanoma cell line and in a mice model of cutaneous melanoma. Cell proliferation was assessed by MTT assay, apoptosis by Annexin V-Fluorescein Isothio…

0301 basic medicine3003MaleSkin NeoplasmsPyridinesPyridinePhytochemicalsMelanoma ExperimentalPharmaceutical ScienceIndicaxanthinApoptosisBcl-2 B cell lymphoma gene-2 (Bcl-2)chemistry.chemical_compoundMice0302 clinical medicineOpuntia Ficus Indica (L.Mill)Settore BIO/10 - BiochimicaDrug DiscoveryCXCL1 chemokine (C-X-C motif) ligand 1MelanomaNF-κB nuclear factor kappa BMTT 3-[45-dimethyltiazol-2-yl]-25-diphenyl tetrazolium bromideMelanomaNF-kappa BOpuntiaComplementary and Alternative Medicine2708 DermatologyBetaxanthinsCXCL1030220 oncology & carcinogenesisMolecular MedicinePhC phytochemicalGrowth inhibitionIndicaxanthinHumanBiologyPhytochemicalNHEM normal human epidermal melanocyte03 medical and health sciencesc-FLIP FLICE-inhibitory proteinIn vivoCell Line TumormedicineAnimalsHumansNeoplasm InvasivenessSkin NeoplasmCell ProliferationNeoplasm InvasiveneInflammationPharmacologyCell growthAnimalDrug Discovery3003 Pharmaceutical ScienceApoptosimedicine.diseaseMice Inbred C57BL030104 developmental biologyComplementary and alternative medicinechemistryTumor progressionList of Abbrevations: AxV-FITC annexin V-fluorescein isothiocyanateBetaxanthinFruitCutaneous melanomaCancer researchPI propidium iodide PIPhytomedicine : international journal of phytotherapy and phytopharmacology
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Targeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular Diseases

2016

Within the family of endogenous gasotransmitters, nitric oxide (NO) is the smallest gaseous intercellular messenger involved in the modulation of several processes, such as blood flow and platelet aggregation control, essential to maintain vascular homeostasis. NO is produced by nitric oxide synthases (NOS) and its effects are mediated by cGMP-dependent or cGMP-independent mechanisms. Growing evidence suggests a crosstalk between the NO signaling and the occurrence of oxidative stress in the onset and progression of vascular diseases, such as hypertension, heart failure, ischemia, and stroke. For these reasons, NO is considered as an emerging molecular target for developing therapeutic stra…

0301 basic medicineAgingPhytochemicalsIschemiaEndogenyReview Article030204 cardiovascular system & hematologyPharmacologyBiologyNitric Oxidemedicine.disease_causeCardiovascular SystemBiochemistryNitric oxide03 medical and health scienceschemistry.chemical_compound0302 clinical medicinemedicineAnimalsHumansVascular Diseasescell biology; aging; biochemistrylcsh:QH573-671GasotransmittersPlants Medicinallcsh:CytologyPolyphenolsCardiovascular AgentsCell BiologyGeneral Medicinemedicine.diseaseDietOxidative StressCrosstalk (biology)030104 developmental biologychemistryHeart failurePlant PreparationsOxidative stressIntracellularPhytotherapySignal TransductionOxidative Medicine and Cellular Longevity
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Potential Health Benefits of Olive Oil and Plant Polyphenols

2018

Beneficial effects of natural plant polyphenols on the human body have been evaluated in a number of scientific research projects. Bioactive polyphenols are natural compounds of various chemical structures. Their sources are mostly fruits, vegetables, nuts and seeds, roots, bark, leaves of different plants, herbs, whole grain products, processed foods (dark chocolate), as well as tea, coffee, and red wine. Polyphenols are believed to reduce morbidity and/or slow down the development of cardiovascular and neurodegenerative diseases as well as cancer. Biological activity of polyphenols is strongly related to their antioxidant properties. They tend to reduce the pool of reactive oxygen species…

0301 basic medicineAntioxidantAnticancer therapy; Hydroxytyrosol; Olea europea; Oleuropein; Olive oil; Polyphenols; Catalysis; Molecular Biology; Spectroscopy; Computer Science Applications1707 Computer Vision and Pattern Recognition; Physical and Theoretical Chemistry; Organic Chemistry; Inorganic Chemistrymedicine.medical_treatmentPhytochemicalsReviewAntioxidantsCatalysilcsh:Chemistrychemistry.chemical_compoundFood sciencelcsh:QH301-705.5Spectroscopyfood and beveragesComputer Science Applications1707 Computer Vision and Pattern RecognitionGeneral Medicineolive oilComputer Science Applicationsvisual_artvisual_art.visual_art_mediumBarkhydroxytyrosolPolyphenolContext (language use)Dark chocolateBiologyCatalysisInorganic Chemistry03 medical and health sciencesfoodOleuropeinOleamedicineAnimalsHumansanticancer therapyPhysical and Theoretical ChemistryMolecular BiologyWinePlant ExtractsOlea europeaOrganic ChemistryPolyphenolsAntineoplastic Agents Phytogenicfood.foodPlant Leaves030104 developmental biologylcsh:Biology (General)lcsh:QD1-999chemistryPolyphenololeuropeinHydroxytyrosolInternational Journal of Molecular Sciences
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Dietary phytochemicals in the protection against oxysterol-induced damage.

2017

The intake of fruits and vegetables is associated with reduced incidence of many chronic diseases. These foods contain phytochemicals that often possess antioxidant and free radical scavenging capacity and show anti-inflammatory action, which are also the basis of other bioactivities and health benefits, such as anticancer, anti-aging, and protective action for cardiovascular diseases, diabetes mellitus, obesity and neurodegenerative disorders. Many factors can be included in the etiopathogenesis of all of these multifactorial diseases that involve oxidative stress, inflammation and/or cell death processes, oxysterols, i.e. cholesterol oxidation products (COPs) as well as phytosterol oxidat…

0301 basic medicineAntioxidantOxysterolmedicine.medical_treatmentPhytochemicalsContext (language use)PhytochemicalPharmacologymedicine.disease_causeBiochemistryAntioxidants03 medical and health scienceschemistry.chemical_compoundOxysterol0302 clinical medicineDiabetes mellitusmedicinePhytosterol oxidation productAnimalsHumansCholesterol oxidation productMolecular BiologyCell DeathAnimalCholesterolPhytosterolOrganic ChemistryHuman chronic diseaseCell BiologyOxysterolsmedicine.diseaseObesity030104 developmental biologyBiochemistrychemistry030220 oncology & carcinogenesisChronic DiseaseAntioxidantOxidative stressHumanChemistry and physics of lipids
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Redox Imbalance and Mitochondrial Release of Apoptogenic Factors at the Forefront of the Antitumor Action of Mango Peel Extract

2021

Today, an improved understanding of cancer cell response to cellular stress has become more necessary. Indeed, targeting the intracellular pro-oxidant/antioxidant balance triggering the tumor commitment to cell demise could represent an advantageous strategy to develop cancer-tailored therapies. In this scenario, the present study shows how the peel extract of mango—a tropical fruit rich in phytochemicals with nutraceutical properties—can affect the cell viability of three colon cancer cell lines (HT29, Caco-2 and HCT116), inducing an imbalance of cellular redox responses. By using hydro-alcoholic mango peel extract (MPE), we observed a consistent decline in thiol group content, which was a…

0301 basic medicineAntioxidantmedicine.medical_treatmentCellPharmaceutical ScienceOrganic chemistryApoptosisphytochemicalArticleAnalytical Chemistry03 medical and health scienceschemistry.chemical_compound0302 clinical medicineQD241-441Downregulation and upregulationCell Line TumorNeoplasmsDrug DiscoverymedicineHumansViability assayPhysical and Theoretical ChemistryMethyl gallateMembrane Potential MitochondrialMangiferaPlant Extractsmitochondrial apoptogenic proteinsphytochemicalsAntineoplastic Agents PhytogenicBcl-2 family proteinCell biologyMitochondriaBcl-2 family proteins030104 developmental biologymedicine.anatomical_structurechemistryChemistry (miscellaneous)030220 oncology & carcinogenesisCancer cellMolecular MedicineVDAC1Oxidation-ReductionIntracellularmitochondria injuryMolecules
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