Search results for "Pies"

showing 10 items of 510 documents

Piedziņas vēršana uz kustamo mantu.

2019

Maģistra darba temats ir “Piedziņas vēršana uz kustamo mantu”. Darba tēmas izvēle ir pamatota ar šī piespiedu izpildes līdzekļa aktualitāti un nemitīgu piemērošanu praksē. Lai ātri un kvalitatīvi pildītu tiesas un citu institūciju nolēmumus, piespiedu izpildes procesā piemērojami piespiedu izpildes līdzekļi. Praksē nereti tieši piedziņas vēršana uz kustamo mantu ir vienīgais veids kā izpildīt tiesas vai citu institūciju nolēmumus, tomēr minētais piespiedu izpildes līdzeklis nav efektīvākais starp citiem piespiedu izpildes līdzekļiem. Neskatoties uz pozitīvu attīstību piespiedu izpildes procesā, Civilprocesa likumā un līdz ar to arī praksē, joprojām pastāv problēmas piemērot piedziņas vēršan…

kustama mantaapķīlāšanapiespiedu izpildes līdzekļilietasJuridiskā zinātne
researchProduct

Cell therapy medicinal product regulatory framework in Europe and its application for MSC-based therapy development

2012

Advanced therapy medicinal products (ATMPs), including cell therapy products, form a new class of medicines in the European Union. Since the ATMPs are at the forefront of scientific innovation in medicine, specific regulatory framework has been developed for these medicines and implemented from 2009. The Committee for Advanced Therapies (CAT) has been established at the European Medicines Agency (EMA) for centralized classification, certification and evaluation procedures, and other ATMP-related tasks. Guidance documents, initiatives, and interaction platforms are available to make the new framework more accessible for small- and medium-sized enterprises, academia, hospitals, and foundation…

lcsh:Immunologic diseases. Allergymesenchymal stem/progenitor cellMesenchymal stem cells (MSC)ImmunologyReview ArticleCertificationBest interestsAgency (sociology)Hospital Exemption authorisationImmunology and AllergyMedicinemedia_common.cataloged_instanceProduct (category theory)European unionHospital Exemptionmedia_commonbusiness.industrynational competent authorityCommittee for Advanced TherapiesCell therapy medicinal product (CTMP)AuthorizationGuidance documentsCommittee for Advanced Therapies (CAT)Engineering managementNew product developmentadvanced therapy medicinal productlcsh:RC581-607businesscell therapy medicinal productAdvanced therapy medicinal product (ATMP)Frontiers in Immunology
researchProduct

No dalītā īpašuma attiecībām izrietošās lietu tiesības

2015

Darbā ir piedāvāta metodoloģija dalītā īpašuma attiecību vietas noteikšanai civiltiesību sistēmā. Atbilstoši piedāvātajai metodoloģijai ir secināts, ka dalītā īpašuma attiecības pašlaik ietver gan zemes īpašuma, gan ēkas īpašuma lietošanas tiesības aprobežojumus, no kuriem ēkas īpašuma aprobežojums atbilst reālnastai, kas apgrūtina ēkas īpašumu par labu zemes īpašumam, bet zemes īpašuma aprobežojums – reālservitūtam, kas apgrūtina zemes īpašumu par labu ēkas īpašumam. Izriet, ka piespiedu zemes nomas līguma loma ir fakultatīva, tas noteic dalītā īpašuma attiecībās uz likuma pamata pastāvošo tiesību izlietošanas un pienākumu veikšanas kārtību.

lietu tiesībanostiprinājums zemesgrāmatādalītais īpašumsreālnastaJuridiskā zinātnepiespiedu zemes noma
researchProduct

Administratīvā aizturēšana

2018

Bakalaura darbā “Administratīvā aizturēšana” ir pētīts un analizēts administratīva aizturēšanas institūta normatīvais regulējums Latvijas Administratīvo pārkāpumu kodeksā un citos normatīvajos aktos, kā arī analizēta pastāvošā problemātika piemērošanai praksē. Ņemot vērā novecojušu, nepilnīgu normatīvo regulējumu un pa vairākiem normatīviem aktiem sadrumstaloto administratīvās aizturēšanas regulējumu, ir konstatējamas nepilnības gan normatīvajos aktos, gan normatīvo aktu piemērošanā praksē, kā rezultātā tiek administratīvi aizturētas personas, kaut gan būtu iespējams panākt likumdevēja mērķi arī citos, personu tiesību respektējošākos veidos, kā arī ir problemātisks administratīvās aizturēša…

lietvedība administratīvā pārkāpuma lietāprocesuālie piespiedu līdzekļiLatvijas Administratīvo pārkāpumu kodekssJuridiskā zinātneadministratīvā aizturēšanaadministratīvi procesuālā aizturēšana
researchProduct

Extracellular Vesicles as Biological Shuttles for Targeted Therapies.

2019

The development of effective nanosystems for drug delivery represents a key challenge for the improvement of most current anticancer therapies. Recent progress in the understanding of structure and function of extracellular vesicles (EVs)—specialized membrane-bound nanocarriers for intercellular communication—suggests that they might also serve as optimal delivery systems of therapeutics. In addition to carrying proteins, lipids, DNA and different forms of RNAs, EVs can be engineered to deliver specific bioactive molecules to target cells. Exploitation of their molecular composition and physical properties, together with improvement in bio-techniques to modify their content are critical iss…

liposomesMolecular compositionBioactive moleculesReviewExtracellular vesiclesCatalysislcsh:ChemistryInorganic Chemistry03 medical and health sciencesExtracellular Vesicles0302 clinical medicineDrug Delivery SystemsPlant-derived extracellular vesicleAnimalsHumanstarget therapiesTarget therapyPhysical and Theoretical ChemistryRNA Small Interferinglcsh:QH301-705.5Molecular BiologySpectroscopy030304 developmental biology0303 health sciencesDrug CarriersChemistryOrganic ChemistryGeneral MedicinePlantsComputer Science ApplicationsStructure and functionCell biologyLiposomeplant-derived extracellular vesicleslcsh:Biology (General)lcsh:QD1-999Pharmaceutical Preparations030220 oncology & carcinogenesisDrug deliverydrug deliveryExtracellular vesicleNanocarriersDrug carrierInternational journal of molecular sciences
researchProduct

Ārvalstu tiešo investīciju un to ietekmējošo makroekonomisko faktoru analīze Latvijas ekonomikā

2021

Ārvalstu tiešās investīcijas ieņem nozīmīgu lomu katras valsts ekonomikas attīstībā un izaugsmē. Tāpat kā visām citām pasaules valstīm, arī Latvijai ir svarīgi piesaistīt papildus kapitālu valsts ekonomikā, tāpēc, lai ĀTI piesaistes politika būtu efektīva, ir jāanalizē vairāki aspekti. Bakalaura darba mērķis ir, pamatojoties uz Latvijas, Lietuvas un Igaunijas Centrālo banku datu analīzi, kā arī starptautisko indeksu un reitingu rādītāju analīzi, identificēt nozīmīgākās Latvijas ekonomikas vājās puses ĀTI piesaistē un izstrādāt priekšlikumus par iespējamajiem Latvijas valdības darbības virzieniem, kuri varētu sekmēt ĀTI piesaisti Latvijas ekonomikā. Izanalizējot situāciju Latvijas ekonomikā,…

makroekonomiskie faktoriĀTI piesaistes politikasalīdzinošā analīzeEkonomikaārvalstu tiešās investīcijasinvestīciju vide
researchProduct

Severe asthma at COVID-19 time: what is new on biologic therapies.

2021

medicine.medical_specialty2019-20 coronavirus outbreakAsthma therapyCoronavirus disease 2019 (COVID-19)business.industrySevere asthmaBiologic therapiesMEDLINECOVID-19General MedicineSettore MED/10 - Malattie Dell'Apparato Respiratoriomedicine.diseaseSeverity of Illness IndexAsthmaAsthma; COVID-19; Humans; Severity of Illness Index; Biological TherapyBiological TherapyInternal medicineSeverity of illnessmedicineHumansbusinessAsthmaHumanMinerva medica
researchProduct

Non-glycemic effects of pioglitazone and incretin-based therapies.

2013

Atherosclerosis and cardiovascular events are highly prevalent and represent the major cause of mortality in patients with type 2 diabetes. Therefore, there is significant interest in the non-glycemic properties of anti-diabetic agents, particularly on those that are effective on cardiovascular risk factors. Thiazolidinediones and incretin-based therapies (IBTs) represent some of the most recent treatment options approved for the management of type 2 diabetes; these agents have shown important glycemic effects, as well as a number of non-glycemic effects. The latter include those on body weight, inflammation, hypertension and dyslipidemia, thus impacting the different components of the meta…

medicine.medical_specialtyAtherosclerosis cardiovascular events type 2 diabetes pioglitazone incretin-based therapiesClinical BiochemistryMEDLINEIncretinType 2 diabetesPharmacologyIncretinsDrug DiscoverymedicineHumansHypoglycemic AgentsIn patientIntensive care medicineGlycemicDyslipidemiasPharmacologyPioglitazonebusiness.industryBody Weightmedicine.diseaseCardiovascular DiseasesMolecular MedicineThiazolidinedionesMetabolic syndromebusinessPioglitazoneDyslipidemiamedicine.drug
researchProduct

Update on the effects of graded motor imagery and mirror therapy on complex regional pain syndrome type 1: A systematic review.

2017

Graded motor imagery (GMI) and mirror therapy (MT) is thought to improve pain in patients with complex regional pain syndrome (CRPS) types 1 and 2. However, the evidence is limited and analysis are not independent between types of CRPS. The purpose of this review was to analyze the effects of GMI and MT on pain in independent groups of patients with CRPS types 1 and 2. Searches for literature published between 1990 and 2016 were conducted in databases. Randomized controlled trials that compared GMI or MT with other treatments for CRPS types 1 and 2 were included. Six articles met the inclusion criteria and were classified from moderate to high quality. The total sample was composed of 171 p…

medicine.medical_specialtyCausalgiaImagery PsychotherapyPopulationPhysical Therapy Sports Therapy and Rehabilitationlaw.invention03 medical and health sciences0302 clinical medicineMotor imageryPhysical medicine and rehabilitationRandomized controlled triallawmedicineHumansOrthopedics and Sports MedicineIn patient030212 general & internal medicineeducationPain Measurementeducation.field_of_studyMind-Body TherapiesRehabilitationChronic painmedicine.diseaseReflex Sympathetic DystrophyComplex regional pain syndromeMirror therapySample size determinationPhysical therapyPsychology030217 neurology & neurosurgeryComplex Regional Pain SyndromesJournal of back and musculoskeletal rehabilitation
researchProduct

Management of giant cell arteritis: Recommendations of the French Study Group for Large Vessel Vasculitis (GEFA).

2016

Abstract Purpose Management of giant cell arteritis (GCA, Horton's disease) involves many uncertainties. This work was undertaken to establish French recommendations for GCA management. Methods Recommendations were developed by a multidisciplinary panel of 33 physicians, members of the French Study Group for Large Vessel Vasculitis (Groupe d’etude francais des arterites des gros vaisseaux [GEFA]). The topics to be addressed, selected from proposals by group members, were assigned to subgroups to summarize the available literature and draft recommendations. Following an iterative consensus-seeking process that yielded consensus recommendations, the degree of agreement among panel members was…

medicine.medical_specialtyConsensusConsensus Development Conferences as TopicGiant Cell ArteritisDiseaseRecommendations03 medical and health sciences0302 clinical medicineLarge vessel vasculitisDiagnosismedicineInternal MedicineHumans030212 general & internal medicineIntensive care medicineExpert TestimonySocieties Medical030203 arthritis & rheumatologyModalitiesbusiness.industryBiologic therapiesGastroenterologyTemporal artery biopsymedicine.diseaseSurgeryTreatmentGiant cell arteritisRegimenAdjunctive treatmentCommittee MembershipFrancebusinessAlgorithmsLa Revue de medecine interne
researchProduct