Search results for "Pilin"

Rapid and specific detection of F17-related pilin and adhesin genes in diarrheic and septicemic Escherichia coli strains by multiplex PCR

1996

The F17-related adhesins are prevalent in Escherichia coli strains isolated from calves with diarrhea or septicemia and from lambs with nephropathy. The F17 family includes the F17a, F17b, F17c, and F111 fimbriae produced by bovine E. coli strains and the G agglutinin produced by human uropathogenic E. coli strains. An easy and inexpensive multiplex PCR method was developed to detect all the F17-related fimbriae and to identify four subtypes of structural subunit genes and two distinct subfamilies of adhesin genes by only two runs of amplification. A strict correlation was observed between the phenotypic assays and the multiplex PCR method when 166 pathogenic E. coli strains isolated from i…

Liver-primed memory T cells generated under noninflammatory conditions provide anti-infectious immunity.

2013

SummaryDevelopment of CD8+ T cell (CTL) immunity or tolerance is linked to the conditions during T cell priming. Dendritic cells (DCs) matured during inflammation generate effector/memory T cells, whereas immature DCs cause T cell deletion/anergy. We identify a third outcome of T cell priming in absence of inflammation enabled by cross-presenting liver sinusoidal endothelial cells. Such priming generated memory T cells that were spared from deletion by immature DCs. Similar to central memory T cells, liver-primed T cells differentiated into effector CTLs upon antigen re-encounter on matured DCs even after prolonged absence of antigen. Their reactivation required combinatorial signaling thro…

Senti chi parla. Su un aspetto dell’attività di parola a partire da Lacan.

2017

The impact of the receptor binding profiles of the vascular endothelial growth factors on their angiogenic features

2013

Abstract Background Vascular endothelial growth factors (VEGFs) are potential therapeutic agents for treatment of ischemic diseases. Their angiogenic effects are mainly mediated through VEGF receptor 2 (VEGFR2). Methods Receptor binding, signaling, and biological efficacy of several VEGFR2 ligands were compared to determine their characteristics regarding angiogenic activity and vascular permeability. Results Tested VEGFR2 ligands induced receptor tyrosine phosphorylation with different efficacy depending on their binding affinities. However, the tyrosine phosphorylation pattern and the activation of the major downstream signaling pathways were comparable. The maximal angiogenic effect stim…

Gestion du pâturage au printemps en système bovin allaitant : diversité des pratiques en Saône-et-Loire

2009

National audience; Grazed grass is the cheapest forage for making meat'. In order to incite farmers to make their forage systems more self-sufficient and thrifty, the 'Chambre d'Agriculture de Saone-et-Loire' (a professional agricultural organization for that departement) has been monitoring for five years the management of spring grazing on 23 farms. The analysis of farmers' practices lead to considerations as to put to the best use the grazed grass, according to the pedo-climatic conditions and the constraints of the farms. With the aim of optimizing the pasture resources in order to limit the purchase of concentrates and to cope with the climatic hazards, the study of the management of s…

Bibliogrāfija – autora devuma sabiedriska prezentācija

2018

Autentiski teksti vidusskolas ķīmijas mācību satura apguvē

2016

Maģistra darbā atbilstoši gadījuma pētījuma dizainam aprakstīts, kā ķīmijas vidusskolas mācību stundās izmantot populārzinātniskus rakstus, lai veidotu mācību tematu saikni ar reālo dzīvi, attīstot arī skolēnu zinātnisko kompetenci. Darbā apskatīta literatūra par mūsdienīgu mācību procesu dabaszinātņu apguvē un autentisku tekstu, īpaši populārzinātnisku tekstu, izmantošanu tā realizēšanā. Pētījumā veikta skolotāju anketēšanu, izveidota populārzinātnisko rakstu datu bāze, izstrādāti metodiskie materiāli populārzinātnisko rakstu izmantošanai ķīmijas stundās un veikta to aprobācija. Veikta arī skolēnu anketēšana pirms un pēc materiālu aprobācijas, secinot, ka izmantotā metode palīdz arī veidot…