Search results for "Pilot Projects"

showing 10 items of 488 documents

Efficacy of a mandibular advancement intraoral appliance (MOA) for the treatment of obstructive sleep apnea syndrome (OSAS) in pediatric patients : a…

2018

Background To evaluate the treatment efficacy of a mandibular advancement intraoral appliance (MOA) for treatment of obstructive sleep apnea syndrome (OSAS) in pediatric patients. Material and Methods Eighteen patients (mean=8.39 years old, women=44.4%) were selected. Sleep disorders, sleep bruxism, and temporomandibular disorders were assessed by the Sleep Disturbance Scale for Children (SDSC), the BiteStrip® (portable SB device), and the Research Diagnostic Criteria for Temporomandibular Disorders, respectively. The clinical diagnosis of OSAS was confirmed with a type 3 portable monitor device (ApneaLinkTM Plus). A silicon-based material MOA was used by patients for 60 days, and the resul…

MaleResearch Diagnostic CriteriaSleep BruxismPilot ProjectsArousal03 medical and health sciences0302 clinical medicineHumansMedicineChildGeneral DentistrySleep Apnea ObstructiveSleep disorderOral Medicine and Pathologybusiness.industryHyperhidrosisResearchSleep apnea030206 dentistryTemporomandibular Joint Disorders:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseSleep in non-human animalsObstructive sleep apneaTreatment OutcomeOtorhinolaryngologyChild PreschoolAnesthesiaUNESCO::CIENCIAS MÉDICASFemaleSurgerymedicine.symptomSleep BruxismbusinessMandibular Advancement030217 neurology & neurosurgery
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The effect of the UP4FUN pilot intervention on objectively measured sedentary time and physical activity in 10-to 12 year old children in Belgium : t…

2012

Published version of an article in the journal: BMC Public Health. Also available from BMC: http://dx.doi.org/10.1186/1471-2458-12-805 Bakckground: The first aim was to examine the effect of the UP4FUN pilot intervention on children’s total sedentary time. The second aim was to investigate if the intervention had an effect on children’s physical activity (PA) level. Finally, we aimed to investigate demographic differences (i.e. age, gender, ethnicity, living status and having siblings) between children in the intervention group who improved in sedentary time and PA at post-test and children in the intervention group who worsened in sedentary time and PA at post-test. Methods: The six weeks …

MaleResearch designGerontologymedicine.medical_specialtyEthnic groupPilot ProjectsIntervention030209 endocrinology & metabolismlaw.inventionVDP::Medical disciplines: 700::Health sciences: 800::Nutrition: 81103 medical and health sciences0302 clinical medicineBelgiumRandomized controlled triallawIntervention (counseling)AccelerometryEpidemiologymedicineMedicine and Health SciencesHumans030212 general & internal medicineChildExerciseChildrenSedentary lifestylePhysical activitybusiness.industrylcsh:Public aspects of medicinePublic Health Environmental and Occupational Healthlcsh:RA1-1270Sedentary behaviour3. Good healthPeer reviewAccelerometerResearch DesignRandomized controlled trialPhysical therapyFemaleSedentary BehaviorBiostatisticsEnergy MetabolismbusinessResearch Article
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Saliva analysis by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS) in orthodontic treatment: first pilot…

2011

Abstract Objective SELDI-TOF-MS (Surface-Enhanced Laser Desorption/Ionization Time-Of-Flight Mass Spectrometry) allows the generation of an accurate protein profile from minimal amounts of biological samples and may executes proteomic profile of saliva. The aim of this work is to compare the proteomic profile of saliva of patients in orthodontic treatment to the beginning of treatment and after three months by using the surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS) technology. Materials and methods Saliva was collected from 14 patients, between the 11 and 17 years, to the beginning of the orthodontic treatment and after three months. Specimens …

MaleSaliva analysis SELDI-TOF-MS orthodontic treatmentSalivaAdolescentProteomePilot ProjectsOrthodonticsSinapinic acidMass spectrometrySensitivity and SpecificityOrthodontics CorrectiveMatrix (chemical analysis)chemistry.chemical_compoundOrthodontic AppliancesSELDI-TOF-MSHumansSalivary Proteins and PeptidesChildSalivaProteomic ProfileChromatographytooth movement; orthodontic treatment; seldi-tof-mstooth movementSurface-enhanced laser desorption/ionizationchemistrySpectrometry Mass Matrix-Assisted Laser Desorption-IonizationFemaleorthodontic treatmentTime-of-flight mass spectrometryseldi-tof-ms
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Gentamicin alters nitric oxide production in semicircular canals and otolith organs.

2010

Objectives/Hypothesis: Intratympanic application of gentamicin is an important therapeutic option to control vertigo spells in Meniere's disease. Low doses eliminate the function of semicircular canal ampullae (SCCA) and saccule in most patients, although utricular function is maintained in many cases. Local alteration in free radical production might be responsible for these differences. Therefore, the gentamicin-induced nitric oxide (NO) production was determined in an animal model using separate organ cultures of SCCA, saccule, and utricle. Study Design: Prospective pilot study in male guinea pigs. Methods: SCCA, saccule, and utricle of 28 guinea pigs were isolated and incubated separate…

MaleSemicircular canalbusiness.industryAminoglycosideGuinea PigsPhysiologyPilot ProjectsAnatomyOrgan cultureNitric OxideSemicircular CanalsOtolithic Membranemedicine.anatomical_structureOtorhinolaryngologyUtriclemedicineLinear ModelsAnimalsInner earSacculeProspective StudiesGentamicinsbusinessOtolithAntibacterial agentThe Laryngoscope
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Down regulation of CD11b and CD18 expression in children with hypercholesterolemia: A preliminary report.

2009

BACKGROUND AND AIM: Cell adhesion molecules play an important role in the development of atherosclerosis mediating the attachment of monocytes to the endothelium. The aim of our study was to assess the cell surface expression of CD11b/CD18 integrin on the phagocytes of children affected by hypercholesterolemia. METHODS AND RESULTS: Twenty-six children with hypercholesterolemia (15 males, mean age 8.3, range 2-18) with a family history of early cardiovascular disease, as well as 26 children with normocholesterolemia matched for gender and age (15 males, mean age 8.3) were studied. Cell surface expression of CD11b/CD18 on peripheral blood mononuclear cells (PBMC) were analyzed by flow cytomet…

MaleSettore MED/09 - Medicina InternaAdolescentEndotheliumEndocrinology Diabetes and MetabolismDown-RegulationMedicine (miscellaneous)Pilot ProjectsCD18Context (language use)Peripheral blood mononuclear cellFlow cytometrychildrencd11b/cd18HumansMedicineFamily historyChildCD18PhagocytesCD11b AntigenNutrition and Dieteticsatherosclerosis; cd11b; cd11b/cd18; cd18; children; hypercholesterolemiahypercholesterolemiamedicine.diagnostic_testbiologybusiness.industryCell adhesion moleculeCD11bLipidsCross-Sectional Studiesmedicine.anatomical_structureIntegrin alpha MCD18 AntigensCase-Control StudiesChild PreschoolImmunologybiology.proteinFemaleatherosclerosisCardiology and Cardiovascular Medicinebusiness
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A pilot study of the effects of RightStart instruction on early numeracy skills of children with specific language impairment

2013

This pilot study investigated the effects of an early numeracy program, RightStart Mathematics (RS), on Finnish kindergartners with specific language impairment (SLI). The study applied a pre-test-instruction-post-test design. The children with SLI (n=9, Mage=82.11 months) received RS instruction two to three times a week for 40 min over seven months, which replaced their business-as-usual mathematics instruction. Mathematical skill development among children with SLI was examined at the individual and group levels, and compared to the performance of normal language-achieving age peers (n=32, Mage=74.16 months) who received business-as-usual kindergarten mathematics instruction. The childre…

MaleShort-term memoryPilot ProjectsSpecific language impairmentDevelopmental psychologyMathematical skillEarly Intervention EducationalDevelopmental and Educational PsychologymedicineHumansLanguage Development Disorders0501 psychology and cognitive sciencesChildMathematics instructionWorking memory4. Education05 social sciencesSignificant differenceSubtraction050301 educationmedicine.diseaseClinical PsychologyEarly numeracyFemalePsychology0503 educationMathematics050104 developmental & child psychologyResearch in Developmental Disabilities
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Rationale and results of the international society of pediatric oncology (SIOP) Italian pilot study on childhood hepatoma: Surgical resectionD'Emblée…

1993

MaleSurgical resectionPediatricsmedicine.medical_specialtyCarcinoma HepatocellularAdolescentBiopsyPilot ProjectsChildhood HepatomaAntineoplastic Combined Chemotherapy ProtocolsPreoperative CarePediatric oncologymedicineHepatectomyHumansPrimary chemotherapyChildbusiness.industryLiver NeoplasmsRemission InductionInfantGeneral MedicineCombined Modality TherapySurvival RateItalyOncologyDoxorubicinChild PreschoolFemaleSurgeryCisplatinbusinessFollow-Up StudiesJournal of Surgical Oncology
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Influence of occlusal loading on peri-implant clinical parameters. A pilot study

2013

Objectives: To investigate the relation between occlusal loading and peri-implant clinical parameters (probing depth, bleeding on probing, gingival retraction, width of keratinized mucosa, and crevicular fluid volume) in pa - tients with implant-supported complete fixed prostheses in both arches. Material and Methods: This clinical study took place at the University of Valencia (Spain) dental clinic. It included patients attending the clinic for regular check-ups during at least 12 months after rehabilitation of both arches with implant-supported complete fixed ceramo-metallic prostheses. One study implant and one control implant were established for each patient using the T-Scan®III comput…

MaleTime FactorsPeriBleeding on probingDentistryPilot ProjectsOdontologíaBite ForceCrevicular fluidmedicineHumansGeneral DentistryOcclusal AdjustmentOrthodonticsbusiness.industryResearchSignificant differenceGingival Crevicular FluidMiddle Aged:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludBite force quotientOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASComputerized systemFemaleSurgeryDental Prosthesis Implant-SupportedImplantPeriodontal Indexmedicine.symptombusinessImplantologyMedicina Oral Patología Oral y Cirugia Bucal
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Peroperative Intravascular Ultrasound for Endovascular Aneurysm Repair versus Peroperative Angiography: A Pilot Study in Fit Patients with Favorable …

2020

The aim of this study was to compare intravascular ultrasound (IVUS) assistance for endovascular aortic aneurysm repair (EVAR) to standard assistance by angiography.From June 2015 to June 2017, 173 consecutive patients underwent EVAR. In this group, 69 procedures were IVUS-assisted with X-ray exposure limited to completion angiography for safety purposes because an IVUS probe does not yet incorporate a duplex probe (group A), and 104 were angiography-assisted procedures (group B). All IVUS-assisted procedures were performed by vascular surgeons with basic duplex ultrasound (DUS) training. The primary study endpoints were mean radiation dose, duration of fluoroscopy, amount of contrast media…

MaleTime FactorsRadiographymedicine.medical_treatmentContrast MediaPilot Projects030204 cardiovascular system & hematologyRadiography InterventionalEndovascular aneurysm repair030218 nuclear medicine & medical imagingEndovascular aortic repairAortic aneurysmPostoperative Complications0302 clinical medicineRisk FactorsIntravascular ultrasoundAortic aneurysm endovascular repair intravascular ultrasoundFluoroscopyAged 80 and overmedicine.diagnostic_testEndovascular ProceduresAngiographyGeneral MedicineMiddle AgedRadiation ExposureTreatment Outcomesurgical procedures operativecardiovascular systemendovascularFemaleRadiologyCardiology and Cardiovascular MedicineAdultmedicine.medical_specialtyAortographyOperative TimeRadiation DosageAortographyintravascular ultrasoundBlood Vessel Prosthesis Implantation03 medical and health sciencesText miningabdominal aortic aneurysmPredictive Value of TestsmedicineHumanscardiovascular diseasesUltrasonography InterventionalAgedRetrospective StudiesIVUSbusiness.industrymedicine.diseaseAngiographySurgerybusinessAortic Aneurysm AbdominalAbdominal surgeryAnnals of Vascular Surgery
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Rate vs. rhythm control and adverse outcomes among European patients with atrial fibrillation

2018

Aim The impact of rate and rhythm control strategies on outcomes in patients with atrial fibrillation (AF) remains controversial. Our aims were: to report use of rate and rhythm control strategies in European patients from the EURObservational Research Program AF General Pilot Registry. Secondly, to evaluate outcomes according to assigned strategies. ........................................................................................................................................................... Methods and results Use of pure rate and rhythm control agents was described according to European regions. 1-year follow-up data were reported. Among rate control strategies, beta-blockers …

MaleTime FactorsRate controlAction PotentialsPilot Projects030204 cardiovascular system & hematologyAmiodaroneAction Potentials/drug effectsHeart Conduction System/drug effectsCardiologists0302 clinical medicineHeart RateRisk FactorsCause of DeathAtrial Fibrillation030212 general & internal medicineRegistriesPractice Patterns Physicians'Cause of deathAged 80 and overAll-cause death; Atrial fibrillation; Major adverse events; Rate control; Registry; Rhythm controlHeart Rate/drug effectsAtrial fibrillationMiddle AgedEuropeTreatment OutcomeCohortCardiologyHealthcare Disparities/trendsRhythm controlFemaleCardiology and Cardiovascular MedicineAnti-Arrhythmia AgentsCardiologists/trendsmedicine.drugmedicine.medical_specialtyMajor adverse eventsRegistryAll-cause deathAnti-Arrhythmia Agents/adverse effectsEurope/epidemiology03 medical and health sciencesHeart Conduction SystemPhysiology (medical)Internal medicineHeart ratemedicineAtrial Fibrillation/diagnosisHumansHealthcare DisparitiesAdverse effectAgedbusiness.industryProportional hazards modelmedicine.diseaseAtrial fibrillationPractice Patterns Physicians'/trendsAtrial fibrillation • Rate control • Rhythm control • Major adverse events • All-cause death • RegistryPropensity score matchingbusiness
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