Search results for "Pilot Projects"

showing 10 items of 488 documents

The LANN technique to reduce postoperative functional morbidity in laparoscopic radical pelvic surgery

2005

BACKGROUND: We investigated the feasibility and advantages of introducing Laparoscopic Neuro-Navigation (LANN) into the field of laparoscopic gynecologic radical pelvic surgery. STUDY DESIGN: In a prospective pilot study, 261 consecutive patients underwent laparoscopic radical pelvic surgery for cervical cancer or deep infiltrating endometriosis of the parametria. During the procedure, dissection and electrostimulation, and consequently, sparing of the pelvic parasympathetic nerves by transection of the parametria, were performed. Postoperative bladder dysfunction was documented. RESULTS: Laparoscopic dissection and electrostimulation of the pelvic splanchnic nerves were feasible in all pat…

endometriosisAdultmedicine.medical_specialtyUterine Cervical Neoplasmmedicine.medical_treatmentVaginal DiseasesUterine Cervical NeoplasmsPilot ProjectsSplanchnic Nerveendometriosis; splanchnic nerve; laparoscopic surgerymedicineHysterectomy VaginalHumansPilot ProjectProspective StudiesPostoperative PeriodEndometriosiProspective cohort studyPelvic surgeryAgedCervical cancerHysterectomybusiness.industryVaginal DiseaseRectal DiseaseSplanchnic NervesMiddle Agedmedicine.diseaselaparoscopic surgeryDeep infiltrating endometriosisSurgeryFeasibility StudieDissectionProspective StudieRectal DiseasesFeasibility StudiesFemaleLaparoscopySurgerybusinessBladder functionPelvic splanchnic nerveHuman
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Effect on Orange Juice of Batch Pasteurization in an Improved Pilot-Scale Microwave Oven

2010

The effects on orange juice batch pasteurization in an improved pilot-scale microwave (MW) oven was evaluated by monitoring pectin methyl-esterase (PME) activity, color, carotenoid compounds and vitamin C content. Trials were performed on stirred orange juice heated at different temperatures (60, 70, 75, and 85 degrees C) during batch process. MW pilot plant allowed real-time temperature control of samples using proportional integrative derivative (PID) techniques based on the infrared thermography temperature read-out. The inactivation of heat sensitive fraction of PME, that verifies orange juice pasteurization, showed a z-value of 22.1 degrees C. Carotenoid content, responsible for sensor…

food.ingredientPectinMicrowave ovenPasteurizationPilot ProjectsAscorbic AcidXanthophyllslaw.inventionBeverageschemistry.chemical_compoundfoodZeaxanthinslawFood PreservationHumansFood scienceMicrowavesCryptoxanthinsOrange juiceChemistryFood preservationbeta CaroteneAscorbic acidPilot plantTasteCryptoxanthinNutritive ValueCitrus sinensisFood ScienceJournal of Food Science
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Synthesis and preliminary in vivo evaluation of well-dispersed biomimetic nanocrystalline apatites labeled with positron emission tomographic imaging…

2015

In recent years, biomimetic synthetic apatite nanoparticles (AP-NPs), having chemical similarity with the mineral phase of bone, have attracted a great interest in nanomedicine as potential drug carriers. To evaluate the therapeutic perspectives of AP-NPs through the mechanisms of action and organs they interact with, the noninvasive monitoring of their in vivo behavior is of paramount importance. To this aim, here the feasibility to radiolabel AP-NPs ("naked" and surface-modified with citrate to reduce their aggregation) with two positron emission tomographic (PET) imaging agents ([F-18]NaF and Ga-68-NO(2)AP(BP)) was investigated. [F-18]NaF was used for the direct incorporation of the radi…

inorganic chemicalsMalepositron emission tomographyMaterials scienceNanoparticleNanotechnologyPilot ProjectsDiffusionNanocapsulesIn vivoBiomimetic MaterialsApatitesMaterials TestingmedicineAnimalsGeneral Materials ScienceChelationWhole Body ImagingColloidsParticle SizeRats Wistarmedicine.diagnostic_testtechnology industry and agriculturenanomedicinecalcium phosphatesPositron emission tomographyIsotope LabelingPositron-Emission Tomographydrug deliveryDrug deliverySurface modificationNanomedicineFeasibility StudiesNanoparticlesRadiopharmaceuticalsDrug carrierCrystallizationACS applied materialsinterfaces
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Analysis of Somatosensory Cortical Responses to Different Electrotactile Stimulations as a Method Towards an Objective Definition of Artificial Senso…

2022

Sensory feedback is a critical component in many human-machine interfaces (e.g., bionic limbs) to provide missing sensations. Specifically, electrotactile stimulation is a popular feedback modality able to evoke configurable sensations by modulating pulse amplitude, duration, and frequency of the applied stimuli. However, these sensations coded by electrotactile parameters are thus far predominantly determined by subjective user reports, which leads to heterogeneous and unstable feedback delivery. Thus, a more objective understanding of the impact that different stimulation parameters induce in the brain, is needed. Analysis of cortical responses to electrotactile afference might be an effe…

magnetoencephalographyMEGbiologypalauteMagnetoencephalographyPilot ProjectsSomatosensory CortexFeedbackfrequency modulationkosketusaistiFeedback SensoryEvoked Potentials Somatosensoryihminen-konejärjestelmätHumansfingersspatiotemporal phenomenaman-machine systems
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Social media use to improve communication on children and adolescent’s health: the role of the Italian Paediatric Society influencers

2021

Abstract Background Fake news on children’s and adolescent health are spreading. Internet availability and decreasing costs of media devices are contributing to an easy access to technology by families. Public health organizations are working to contrast misinformation and promote scientific communication. In this context, a new form of communication is emerging social media influencers. Aim of this study is to evaluate the role of paediatric influencers (PI) in communicating information about children and adolescents’ health. Materials and methods A group of PI was enrolled from December 2019 to January 2020 by a scientific commission nominated by the Italian Paediatric Society (SIP). PI w…

medicine.medical_specialtyAdolescentAdolescent HealthContext (language use)Pilot ProjectsPediatricsRJ1-570Social mediaInfluencermedicineHumansSocial mediaPilot ProjectMisinformationChildChildrenSocieties MedicalPediatricConsumer Health Informationbusiness.industryPublic healthResearchCommunicationChild HealthHealth InfluencerAdvertisingInfluencer marketingHealthThe InternetbusinessScientific communicationAdolescent healthHumanItalian Journal of Pediatrics
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Neprilysin inhibition, endorphin dynamics, and early symptomatic improvement in heart failure: a pilot study

2020

Altres ajuts: This work was supported in part by Fundació La Marató de TV3 (201516-10, 201502-30), Societat Catalana de Cardiologia, "la Caixa" Banking Foundation. Altres ajuts: PERIS/SLT002-16-00234 Sacubitril/valsartan is a first-in-class angiotensin receptor-neprilysin inhibitor developed for the treatment of heart failure with reduced ejection fraction. Its benefits are achieved through the inhibition of neprilysin (NEP) and the specific blockade of the angiotensin receptor AT1. The many peptides metabolized by NEP suggest multifaceted potential consequences of its inhibition. We sought to evaluate the short-term changes in serum endorphin (EP) values and their relation with patients' p…

medicine.medical_specialtyAngiotensin receptorEndorphins; Heart failure; Neprilysin; Sacubitril/valsartan; α-Endorphin; γ-Endorphinα‐EndorphinVascular damage Radboud Institute for Health Sciences [Radboudumc 16]HemodynamicsPilot ProjectsHeart failure030204 cardiovascular system & hematologyγ‐EndorphinvalsartanSacubitril03 medical and health sciences0302 clinical medicineOriginal Research ArticlesInternal medicinemedicineHumansDiseases of the circulatory (Cardiovascular) systemalpha-EndorphinOriginal Research ArticleProspective Studies030212 general & internal medicineSacubitril/valsartanγ-EndorphinAngiotensin II receptor type 1Ejection fractionbusiness.industryα-EndorphinStroke Volumegamma-Endorphinmedicine.diseaseSacubitrilValsartanRC666-701Heart failureCardiologyNeprilysinEndorphinsCardiology and Cardiovascular MedicinebusinessSacubitril Valsartanmedicine.drug
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Food as medicine in psychiatric care: Which profession should be responsible for imparting knowledge and use of omega-3 fatty acids in psychiatry

2011

Accepted version of an article in Complementary Therapies in Clinical Practice, 17 (2011), 107-112. Also available from the publisher: http://dx.doi.org/10.1016/j.ctcp.2010.08.001 The effect of omega-3 fatty acids on depression is well documented. The purpose of this study was to determine if and how food is used as medicine in psychiatric care, especially how omega-3 fatty acids are used as a supplement in the treatment of depression. This is a pilot study with a qualitative design using questionnaires and interviews among nursing students, tutor nurses and psychiatrists. Three main categories emerged: 1. Nutrition is considered important but few evaluations are made. 2. There was a lack o…

medicine.medical_specialtyAttitude of Health PersonnelAlternative medicinePilot ProjectsInterviews as TopicProfessional CompetenceProfessional RolePatient Education as TopicSurveys and QuestionnairesFatty Acids Omega-3medicineHumansLack of knowledgeMedical nutrition therapyTUTORPsychiatryDepression (differential diagnoses)Qualitative Researchcomputer.programming_languagePsychiatryDepressive DisorderSocial Responsibilitybusiness.industryDepressionDietary FatsVDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710Peer reviewOmega 3 fatty acids psychiatric care CAMComplementary and alternative medicineQualitative designDietary SupplementsHealth educationbusinesscomputer
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Simulation for training in sinus floor elevation: new surgical bench model

2011

Objectives: to describe a bench model (workshop of abilities) for sinus floor elevation (SFE) training that simulates the surgical environment and to assess its effectiveness in terms of trainees’ perception. Study design: thirty-six randomly selected postgraduate students entered this cross-sectional pilot study and asked to fill in an anonymous, self-applied, 12-item questionnaire about a SFE workshop that included a study guide containing the workshop’s details, supervised practice on a simulated surgical environment, and assessment by means of specific check-lists. Results: Thirtiy-six fresh sheep heads were prepared to allow access to the buccal vestible. Using the facial tuber, third …

medicine.medical_specialtyBench modelStudy guideOral Surgical ProcedureseducationSinus Floor AugmentationPilot ProjectsEducation Dental GraduateSinus floor elevationmedicineAnimalsMedical physicsGeneral DentistryMedian scoreSheep:CIENCIAS MÉDICAS [UNESCO]SurgeryClinical PracticeCross-Sectional StudiesOtorhinolaryngologyModels AnimalUNESCO::CIENCIAS MÉDICASResorbable membranesResearch-ArticleSurgeryOral SurgeryCommunication skillsPsychologyMedicina Oral Patología Oral y Cirugia Bucal
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Is cell salvage safe in liver resection? A pilot study

2007

Abstract Study Objective To investigate the quality of cell salvaged (CS) blood in patients undergoing hemihepatectomy (study group) and compare it with CS-blood from aortic surgery (control group). Design Observational study. Setting Operating room in a university hospital. Measurements 6 patients undergoing hemihepatectomy or aortobifemoral bypass with intraoperative blood loss of more than 800 mL. Samples were drawn from the central venous catheter, from the reservoir of a CS recovery system, and from the processed blood in each patient to determine interleukin (IL)-6, IL-8, IL-10, tumor necrosis factor (TNF), complement C3a, and the terminal complement complex C5b-9. Microbiological ana…

medicine.medical_specialtyBlood transfusionmedicine.medical_treatmentCellPilot ProjectsComplement Membrane Attack ComplexResectionBlood Transfusion AutologousmedicineHepatectomyHumansInterleukin-6business.industryInterleukin-8InterleukinBacterial InfectionsInterleukin-10Complement systemSurgeryAnesthesiology and Pain Medicinemedicine.anatomical_structureCytokineComplement C3aErythrocyte TransfusionbusinessAnaerobic exerciseCentral venous catheterJournal of Clinical Anesthesia
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Successful treatment of axillary hyperhidrosis with very low doses of botulinum toxin B: a pilot study

2003

medicine.medical_specialtyBotulinum ToxinsInjections SubcutaneousTreatment outcomePilot ProjectsSweatingDermatologyAxillary hyperhidrosismedicineHumansHyperhidrosisBotulinum Toxins Type AInjections subcutaneousHyperhidrosisbusiness.industryLow doseGeneral MedicineDermatologyBotulinum toxinSurgeryAxillaAutonomic nervous systemTreatment Outcomemedicine.anatomical_structureAxillamedicine.symptombusinessmedicine.drugArchives of Dermatological Research
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