Search results for "Pines"
showing 10 items of 421 documents
Effects of endotoxin on neurally-mediated gastric acid secretion in the rat.
1998
Abstract The effects of a peripheral administration of E. coli endotoxin on neurally-mediated gastric acid secretion and the role of endogenous opioids or PAF receptors in endotoxin effects have been evaluated in the continuously perfused stomach of the anaesthetized rat. Gastric acid secretion stimulated by distension (20 cm H2O) was reduced dose-dependently by single intravenous bolus injection of endotoxin (0.1–10 μg kg−1). Doses of 5 μg kg−1 induced a peak reduction of distension-stimulated acid output and significantly reduced the secretory response induced by an intravenous bolus of 2-deoxy-d-glucose (150 mg kg−1). This dose of endotoxin did not significantly modify mean systemic arte…
Rational Choice Theory and the Environment: Variants, Applications, and New Trends
2010
Rational choice theory (RCT) is a research paradigm based on methodological individualism. Collective phenomena are explained by assumptions about the behavior of (subjectively) rational individual or corporate actors. In environmental research, RCT is used to predict ecological perceptions, attitudes and behavior on the micro level, and to shed light on environmental outcomes on the macro level. The most fundamental insight from RCT is that environmental problems are often the result of a social dilemma, that is, individuals’ purposive action leads to unintended negative collective consequences. This chapter addresses variants of RCT including game theory, shows applications in the field o…
On Martial Law at 50 : Fact-Checking the Marcos Story, Countering the EDSA History
2022
To fact-check and counter the historical denialism of the Marcos family, there is need for a counterfactual history analysis of the failings of the 1986 EDSA People Power Revolution. nonPeerReviewed
The human side of leadership: Inspirational leadership effects on follower characteristics and happiness at work (HAW)
2020
Abstract Leadership has received significant attention over the past years. Now is the time to refine how leaders impact on followers and their attitudes. This study examines how inspirational leaders influence follower characteristics (FC), and in turn, their happiness at work. In this study, the mediating effect of follower characteristics in the relationship between inspirational leadership and happiness at work was specifically examined. Data was gathered from 389 frontline banking employees working in Italian and Spanish banks. A confirmatory factor analysis revealed a positive partial mediating role of follower characteristics in the relationship between inspirational leadership and h…
Development and evaluation of occlusive systems employing polyvinyl alcohol for transdermal delivery of sumatriptan succinate
2010
The aim of the present study was to develop a sumatriptan succinate transdermal system for applying migraine treatments efficiently and easily. For this system polyvinyl alcohol was employed as a matrix and Azone((R)) was added as a permeability enhancer. The physical characteristics, mechanical properties, and in vivo bioadhesion of the systems were evaluated, as was in vitro permeation across porcine skin. A uniform distribution of the drug in the matrix was observed, and moisture uptake values were constant. With regard to mechanical parameters, occlusive layer inclusion made the system more resistant, and no significant differences were detected with respect to other systems. Although A…
Attentional biases toward emotional images in the different episodes of bipolar disorder: an eye-tracking study.
2014
Attentional biases toward emotional information may represent vulnerability and maintenance factors in bipolar disorder (BD). The present experimental study examined the processing of emotional information in BD patients using the eye-tracking technology. Bipolar patients in their different states (euthymia, mania, depression) simultaneously viewed four pictures with different emotional valence (happy, neutral, sad, threatening) for 20 s while their eye movements were monitored. A group of healthy individuals served as the control. The data revealed the following: (i) a decrease in attention to happy images in BD patients in their depressive episodes compared to healthy individuals, and (ii…
Synthesis and antiproliferative activity of 3-(2-chloroethyl)-5-methyl-6-phenyl-8-(trifluoromethyl)-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4-(…
2015
Based on the encouraging results found for 3,5-dimethyl-6-phenyl-8-(trifluoromethyl)-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4-(3H)-one 7 previously tested by us, as well as the consideration that heterocycle fused tetrazepinones bearing the 2-chloroethyl substituent show a better cytotoxic profile than temozolomide and mitozolomide against human cancer cell lines which express the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT), in this paper we report the multistep synthesis and the biological study of 3-(2-cloroethyl)-5-methyl-6-phenyl-8-(trifluoromethyl)-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4-(3H)-one 10. Like compound 7, it was active on P-glycoprotein e…
Metro Manila’s competing business districts; Edge Cities, Philippine style ?
2016
International audience
Feasibility of the Internet Attachment-Based Compassion Therapy in the General Population: Protocol for an Open-Label Uncontrolled Pilot Trial
2020
Background Compassion-based interventions delivered over the internet are showing promising results for the promotion of psychological health and well-being. Several studies have highlighted their feasibility, acceptance, and preliminary efficacy. However, this is an incipient field of research, and to the best of our knowledge, there are no data available from Spanish-speaking countries. Objective The aim of this study is to investigate the feasibility, acceptance, and preliminary efficacy of the Internet Attachment–Based Compassion Therapy (iABCT), a web-based version of the Attachment-Based Compassion Therapy, in Spanish speakers from the general population. Methods This feasibility stu…
Copia de carta en forma de Breve
Precedeix al tít.: [creu de Malta Còpia certificada amb signatura ms.: "Franco. Rodriguez de Penin" Carta en llatí Filets Text a 1 col