Search results for "Piper"
showing 10 items of 632 documents
Comparison of two partial least squares infrared spectrometric methods for the quality control of pediculosis lotions.
2006
Two vibrational spectroscopy procedures have been developed and compared for the direct and simultaneous determination of piperonyl butoxide and tetramethrin, the active ingredients of alcoholic capillary lotions, for hair pediculosis diseases. Nine lotions, purchased from the Spanish market, were analyzed using both, attenuated total reflectance (ATR) and transmission FT-IR measurements, and based on the use of partial least squares (PLS) multivariate calibration. A reduced set of 15 matched standards (11 for calibration and 4 for validation) was employed using both measurement modes. The spectral wave number ranges between 1757 and 1712 cm(-1) was selected to determine tetramethrin by bot…
Dragon method for finding novel tyrosinase inhibitors: Biosilico identification and experimental in vitro assays
2006
QSAR (quantitative structure-activity relationship) studies of tyrosinase inhibitors employing Dragon descriptors and linear discriminant analysis (LDA) are presented here. A data set of 653 compounds, 245 with tyrosinase inhibitory activity and 408 having other clinical uses were used. The active data set was processed by k-means cluster analysis in order to design training and prediction series. Seven LDA-based QSAR models were obtained. The discriminant functions applied showed a globally good classification of 99.79% for the best model Class=-96.067+1.988 x 10(2)X0Av +9 1.907 BIC3 + 6.853 CIC1 in the training set. External validation processes to assess the robustness and predictive pow…
Transintestinal secretion of ciprofloxacin, grepafloxacin and sparfloxacin: in vitro and in situ inhibition studies.
2003
The influence of the secretion process on the absorption of ciprofloxacin, grepafloxacin and sparfloxacin has been evaluated by means of inhibition studies. Two well known P-glycoprotein inhibitors (cyclosporine, verapamil), a mixed inhibitor of P-glycoprotein and the organic cation transporter OCT1 (quinidine) and a well established MRP substrate (p-aminohipuric acid) have been selected in order to distinguish the possible carriers implicated. An in situ rat gut perfusion model and CACO-2 permeability studies are used. Both methods suggest the involvement of several types of efflux transporters for every fluoroquinolone. The relevance of the secretory pathway depends on the intrinsic perme…
Carnosine inhibits amyloid fibril formation of alpha crystallin under destabilizing conditions
2008
Inhibition of α-crystallin amyloid fibrils formation by carnosine
2008
Effect of the heat treatment on α-crystallin : characterisation of amyloid fibrils formation and inhibitory effect of carnosine
2009
Migration patterns and fat reserves of Curlew Sandpipers Calidris ferruginea at a stopover site in southern Italy
2006
The Volturno Plain, southern Italian coast, is a regular stopover site for Curlew Sandpipers during northward migration. During 1992–1998, 2,177 Curlew Sandpipers were ringed and measured on northward migration; numbers trapped each year fluctuated. Peak passage was during the period 6–10 May, with 94% of birds trapped in the period 1–20 May. Median date of passage of males preceded females by about five days. Using a new visual method to evaluate fat deposition in waders, there was a strong correlation between body weight and visually estimated fat deposits. Birds showed a mass increase of 2.8 g/day. The mean stopover duration was 2.2 days. Only 0.9% of the total catch of Curlew Sandpipers…
Halogen bonding drives the self-assembly of piperazine cyclophanes into tubular structures.
2009
Halogen bonding with 1,4-diiodotetrafluorobenzene leads to the self-assembly of piperazine cyclophanes into well-defined tubular structures with solvent inclusion.
CCDC 1822973: Experimental Crystal Structure Determination
2019
Related Article: Krzysztof M. Borys, Alicja Matuszewska, Dorota Wieczorek, Karolina Kopczyńska, Jacek Lipok, Izabela D. Madura, Agnieszka Adamczyk-Woźniak|2019|J.Mol.Struct.|1181|587|doi:10.1016/j.molstruc.2019.01.018
CCDC 104616: Experimental Crystal Structure Determination
1999
Related Article: J.Ratilainen, K.Airola, R.Frohlich, M.Nieger, K.Rissanen|1999|Polyhedron|18|2265|doi:10.1016/S0277-5387(99)00117-5