Search results for "Piperidine-2"
showing 4 items of 4 documents
Diastereoselective synthesis of 6-functionalized 4-aryl-1,3-oxazinan-2-ones and their application in the synthesis of 3-aryl-1,3-aminoalcohols and 6-…
2010
Abstract Halocyclocarbamation of benzyl N -(1-phenyl-3-butenyl)carbamates afforded 6-functionalized 4-aryl-1,3-oxazinan-2-ones with moderate to excellent diastereoselectivity depending on the N -substituent. Importantly, in contrast to reported cyclocarbamations of homoallylic carbamates, which are generally trans -diastereoselective, cyclization of N -unsubstituted Cbz-protected homoallylamines led to cis -1,3-oxazinan-2-ones, predominantly. The use of N -benzylated and in situ prepared N -silylated derivatives resulted however in trans -selectivity. Transition states are proposed to explain the stereochemical influence of the N -substituent on the cyclocarbamations. The functionalized 1,3…
CCDC 1483077: Experimental Crystal Structure Determination
2017
Related Article: Vittorio Pace, Wolfgang Holzer, Guangrong Meng, Shicheng Shi, Roger Lalancette, Roman Szostak, Michal Szostak|2016|Chem.-Eur.J.|22|14494|doi:10.1002/chem.201603543
CCDC 1969085: Experimental Crystal Structure Determination
2020
Related Article: Md. Mahbubur Rahman, Chengwei Liu, Elwira Bisz, Błażej Dziuk, Roger Lalancette, Qi Wang, Hao Chen, Roman Szostak, Michal Szostak|2020|J.Org.Chem.|85|5475|doi:10.1021/acs.joc.0c00227
CCDC 1969082: Experimental Crystal Structure Determination
2020
Related Article: Md. Mahbubur Rahman, Chengwei Liu, Elwira Bisz, Błażej Dziuk, Roger Lalancette, Qi Wang, Hao Chen, Roman Szostak, Michal Szostak|2020|J.Org.Chem.|85|5475|doi:10.1021/acs.joc.0c00227