Search results for "Placement."
showing 10 items of 1123 documents
Fast Axial Scanning in 3D Imaging
2016
We establish the conditions for obtaining fast axial 3D microscopy with constant magnification, invariant resolution, and symmetrical displacement range. We demonstrate that liquid lenses permit the axial scanning free of mechanical movements and vibrations. This allows speeding-up the process and avoiding distortionsin the image of dynamic specimens. Article not available.
Asymptotic observer of the link states of flexible joint robots with motor-side sensing
2015
This paper proposes an approach for observing the link states, i.e. angular position and velocity, of the robotic joints with elasticities, when only the motor-side sensing is available. By separating the state-dependent nonlinearities of the rigid manipulator dynamics a linear sub-model of the elastic joint robot is obtained in an observable state-space form. The standard asymptotic Luenberger state observer is then designed for the given motor position signal which is measured by encoder and rectified from the nonlinear contribution. The configurable poles of observer allow shaping the estimated states dynamics to be fast enough in relation to the actual resonant joint behavior. Therefore…
Treatment of Anderson-Fabry Disease
2020
Fabry disease is an X-linked disorder of glycosphingolipid metabolism that results in progressive accumulation of neutral glycosphingolipids, predominantly globotriaosylsphingosine (Gb3) in lysosomes, as well as other cellular compartments of several tissues, causing multi-organ manifestations (acroparesthesias, hypohidrosis, angiokeratomas, signs and symptoms of cardiac, renal, cerebrovascular involvement). Pathogenic mutations lead to a deficiency of the lysosomal enzyme alpha-galactosidase A (GLA). In the presence of high clinical suspicion, a careful physical examination and specific laboratory tests are required. Finally, the diagnosis of Fabry’s disease is confirmed by the demonstrat…
Evaluation of the long-term treatment effects of idursulfase using statistical modelling: Data from the Hunter Outcome Survey (HOS)
2019
Treatment for mucopolysaccharidosis type II (MPS II Hunter syndrome) is available in the form of intravenous enzyme replacement therapy (ERT) with idursulfase (Shire, Lexington, MA, USA). This analysis used statistical modelling to evaluate the long-term treatment effects of idursulfase on selected clinical parameters based on data from HOS, a global, observational registry (Shire, Lexington, MA, USA). Mixed modelling was used to analyse data from male patients followed prospectively in HOS who had received idursulfase for 5-8 years and information available for two or more timepoints, of which one was pre-ERT. Data were excluded from patients with only pre-ERT information available, who ha…
Optimal placement of quality sensors in water distribution systems
2019
Water supply infrastructures are crucial for the sustainable existence and development of modern cities [1,2]. Water distribution systems (WDSs) are complex structures formed by many elements designed and erected to transport water of sufficient quality from water sources to consumers. The amount of the above elements, which can reach up to tens of thousands of links and junctions, their frequently wide spatial dispersion and the WDS characteristic of being very dynamic structures make the management of real WDSs a complex problem [3-5]. Moreover, although the main objective is to supply water in the quantity and quality required, other requirements are essential, namely maintaining conditi…
Elastic waves in random-fibre networks
1997
The propagation of the first displacement maximum of a semi-infinite wavetrain in a two-dimensional random-fibre network is analysed. Model calculations and numerical simulations are used for demonstrating that two qualitatively different wavefront velocities appear in the network. A transient wave, which travels fast and whose amplitude decreases exponentially, dominates the short-time behaviour when the bending stiffness of the fibres is small and the driving frequency is high. This mode can be described by a one-dimensional model. The transient-wave mode propagates even if the bending stiffness of the fibres vanishes, in which case the normal sound velocity is zero. The usual, and slower…
Interspecific territoriality in Calopteryx damselflies: the role of secondary sexual characters
2006
Interspecific territoriality is usually interpreted to result from interspecific interference competition, although it may also originate from mistaken species recognition. In the latter case, it may be based on similarity of secondary sexual characters. In the damselfly Calopteryx splendens, males have pigmented wing spots as a sexual character, and males with the largest spots resemble males of another species, Calopteryx virgo. Probably because of this resemblance, C. virgo males are more aggressive towards large- than small-spotted C. splendens males. We examined whether wing spot size of C. splendens males affects territorial interactions between the species. In a removal experiment, t…
Experimental determination of mode I fracture parameters in orthotropic materials by means of Digital Image Correlation
2020
Abstract The mode I fracture parameters for an orthotropic body are directly calculated from full-field deformation measurements provided by Digital Image Correlation (DIC). Three complementary and direct approaches are evaluated and compared: (i) the determination of the Stress Intensity Factor (SIF) by fitting the displacement field using the analytical expression proposed by Lekhnitskii; (ii) the determination of the J-Integral by using the Energy Domain Integral (EDI) formulation on the raw DIC data; and (iii) the calculation of the J-Integral using the EDI approach on the displacement data fitted using Lekhnitskii’s formulation. A comparative experimental study is performed by testing …
Limit analysis of a beam in bending immersed in an elastoplastic medium
1968
The behavior of the beam-soil system is examined within the scope of the bilateral schematization of ideal elastoplastic bodies, in the following work stages; the expression for the limit load is supplied for each stage: Two peculiar features of the problem are highlighted:1) the “plastic hinge migration” phenomenon, due to the elastic unloading of the material, and2) the successive propagation of plastification in the soil which, being related to the displacement of the hinges in the beam, leads to the identification of the collapse mechanism of the systme.
The interphase model applied to the analysis of masonry structures
2014
Abstract Masonry material presents a mechanical response strongly dependent on the static and kinematic phenomena occurring in the constituents and at their joints. At the mesoscopic level the interaction between the units is simulated by means of specific mechanical devices such as the zero thickness interface model where the contact tractions and the displacement discontinuities are the primary static and kinematic variables respectively. In many cases the joint response depends also on internal stresses and strains within the interface layer adjacent to the joint interfaces. The introduction of internal stresses and strains leads to the formulation of the interphase model, a sort of enha…