Search results for "Planetary Science"
showing 10 items of 4367 documents
Does Metformin Modulate Mitochondrial Dynamics and Function in Type 2 Diabetic Patients?
2021
Metformin is an effective drug against type 2 diabetes (T2D), a pathogenesis in which mitochondrial dysfunction is one of the main players. Thus, our first aim was to describe the effect of metform...
New insights from recently migrated CROP multichannel seismic data at the outermost Calabrian arc accretionary wedge (Ionian sea)
2011
This study addresses selected aspects of the stratigraphic-structural setting of the outermost Calabrian Arc accretionary wedge and underlines relationships between structural development and Messinian evaporite stratigraphy through the analysis of re-processed CROP multichannel seismic reflection profiles. A detailed seismostratigraphic analysis, calibrated with P-velocities compiled by previous works, images a general bipartition of the Messinian evaporite deposits: the transparent «lower subunit» appears to have undergone ductile-flow deformation», with the development of salt-cored thrusting structures, and the layered «upper subunit» appears to be characterized by brittle deformation. …
E-heutagogy for lifelong e-learning
2012
Abstract The paper aims to introduce a new concept: e-heutagogy. This aim is approached through two sub-objectives:a) Giving the rationale for the new concept of e-heutagogy.b) Outlining the features of e-heutagogy necessary for lifelong e-learning.Why do we need a new concept? Learning is a complex concept and it is a part of our entire life. Today we can speak about new generations of learners at all levels, from kindergarten to university, not only due to technology but also due to rapid changes in open, heterogeneous, dynamic and uncertain environments.Taking into account that heutagogy is appropriate to the needs of learners but learners are most of their life without their teachers an…
The Repertoire of Tissue Inhibitors of Metalloproteases: Evolution, Regulation of Extracellular Matrix Proteolysis, Engineering and Therapeutic Chall…
2022
Tissue inhibitors of metalloproteases (TIMPs) belong to a fascinating protein family expressed in all Metazoa. They act as regulators of the turnover of the extracellular matrix, and they are consistently involved in essential processes. Herein, we recapitulate the main activities of mammalian TIMPs (TIMP1–4) in the control of extracellular-matrix degradation and pathologies associated with aberrant proteostasis. We delineate the activity of TIMPs in the control of extracellular matrix (ECM) homeostasis and discuss the diversity of TIMPs across metazoans taking into account the emergence of the components of the ECM during evolution. Thus, the TIMP repertoire herein analysed includes the ho…
The thin and medium filters of the EPIC camera on-board XMM-Newton: measured performance after more than 15 years of operation
2016
After more than 15 years of operation of the EPIC camera on board the XMM-Newton X-ray observatory, we have reviewed the status of its Thin and Medium filters. We have selected a set of Thin and Medium back-up filters among those still available in the EPIC consortium and have started a program to investigate their status by different laboratory measurements including: UV/VIS transmission, Raman scattering, X-Ray Photoelectron Spectroscopy, and Atomic Force Microscopy. Furthermore, we have investigated the status of the EPIC flight filters by performing an analysis of the optical loading in the PN offset maps to gauge variations in the optical and UV transmission. We both investigated repea…
The response of calcareous nannoplankton to sea surface variability at Ceara Rise during the early Pleistocene glacial-interglacial cycles
2019
The Ceara Rise lies just beyond the edge of the Amazon River Fan and sediments from this site may record the complex interplay of different climatic systems and processes, including past changes in southern America monsoon activity, Intertropical Convergence Zone setting, different Atlantic Meridional Overturning Circulation (AMOC) strength and phytoplankton blooming triggered by Amazon River plumes. Here we investigate early Pleistocene calcareous nannoplankton at Ceara Rise, between about 1150 and 850 kiloyears ago. Our investigation shows abrupt variations in water column dynamics across glacial/interglacial cycles or, even better, linked with different AMOC modes. Dominant placoliths in…
DIDÁCTICA DE LAS ARTES CON TIC, APRENDIZAJE COLABORATIVO E INTERDISCIPLINARIEDAD EN LA FORMACIÓN INICIAL DEL PROFESORADO
2021
El aprendizaje mediante las tecnologías de la información y comunicación y la interdisciplinariedad como ejes de la innovación pedagógica son aspectos que se deben fomentar en la Educación Superior desde la declaración de Bolonia, hace ya veinte años. Sin embargo, todavía no han arraigado lo suficiente en muchas aulas universitarias. Es por ello que se presenta un estudio sobre una experiencia educativa desarrollada por profesorado de las áreas de didáctica de la expresión musical, plástica y corporal con futuros docentes en formación. Los objetivos son promover el uso de las TIC, nuevos sistemas de comunicación de los trabajos académicos y el aprendizaje colaborativo e interdisciplinar ent…
Walking on exoplanets: Is Star Wars right?
2016
As the number of detected extrasolar planets increases, exoplanet databases become a valuable resource, confirming some details about planetary formation, but also challenging our theories with new unexpected properties.
New constraints on the presence of debris disks around G 196-3 B and VHS J125601.92-125723.9 b
2023
We obtained deep images of G 196-3 B and VHS J1256-1257 b with the NOrthern Extended Millimeter Array (NOEMA) at 1.3 mm. These data were combined with recently published Atacama Large Millimeter Array (ALMA) and Very Large Array (VLA) data of VHS J1256-1257 b at 0.87 mm and 0.9 cm, respectively. Neither G 196-3 B nor VHS J1256-1257 b were detected in the NOEMA, ALMA and VLA data. At 1.3 mm, we imposed flux upper limits of 0.108 mJy (G 196-3 B) and 0.153 mJy (VHS J1256-1257 b) with a 3-sigma confidence. Using the flux upper limits at the millimeter and radio wavelength regimes, we derived maximum values of 0.016 M$_{\rm Earth}$ and 0.004 M$_{\rm Earth}$ for the mass of any cold dust that mig…
A hemispherical dynamo model : Implications for the Martian crustal magnetization
2014
Abstract Mars Global Surveyor measurements revealed that the Martian crust is strongly magnetized in the southern hemisphere while the northern hemisphere is virtually void of magnetization. Two possible reasons have been suggested for this dichotomy: a once more or less homogeneously magnetization may have been destroyed in the northern hemisphere by, for example, resurfacing or impacts. The alternative theory we further explore here assumes that the dynamo itself produced a hemispherical field ( Stanley et al., 2008 , Amit et al., 2011 ). We use numerical dynamo simulations to study under which conditions a spatial variation of the heat flux through the core–mantle boundary (CMB) may yiel…