Search results for "Plaque"

showing 10 items of 334 documents

Therapeutic modulation of lipoprotein-associated phospholipase A2 (Lp-PLA2)

2011

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a calcium-independent phospholipase A2 that circulates in plasma in association with lipoprotein particles, whereas in atherosclerotic plaques it is co-localized with macrophages. Lp-PLA2 generates two proinflammatory mediators, lysophosphatidylcholine and oxidized nonesterified fatty acids, which play a role in the development of atherosclerotic lesions and formation of a necrotic core, leading to more vulnerable plaques. Epidemiologic studies demonstrate that increased circulating levels of Lp-PLA2 predict an increased risk of myocardial infarction, stroke and cardiovascular mortality. Furthermore, histologic examination of diseased hum…

RiskPathologymedicine.medical_specialtycoronary-artery-diseasecardiovascular-diseasePharmacologyatherosclerotic plaqueProinflammatory cytokinechemistry.chemical_compoundPhospholipase A2cardiovascular diseaseDarapladibOximesDrug DiscoveryHyperlipidemiamedicineHumansMyocardial infarctionPharmacologyClinical Trials as Topicbiologylow-density-lipoproteinLipoprotein-associated phospholipase A2risk-assessmentCardiovascular AgentsAtherosclerosismedicine.diseaselp-pla2heart-diseaselipoproteinsLysophosphatidylcholinechemistryCardiovascular DiseasesinflammationBenzaldehydes1-Alkyl-2-acetylglycerophosphocholine Esterasebiology.proteindarapladibrheumatoid-arthritislipids (amino acids peptides and proteins)atherosclerosisfactor-acetylhydrolase activityAtherosclerosis Cardiovascular disease Darapladib Inflammation Lipoproteins Lp-PLA2.platelet-activating-factorsecondary preventionLipoprotein
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Effect of two prophylaxis methods on adherence of Streptococcus mutans to microfilled composite resin and giomer surfaces

2010

Objectives: Surface attributes of a restoration play an important role in adherence of plaque bacteria. Prophylaxis methods may be involved in modification of or damaging the restoration surface. The aim of the present study was to evaluate the effect of two prophylaxis methods on adherence of Streptococcus mutans to the surface of two restorative materials. Study design: A total of 60 specimens were prepared from each material; a microfilled composite resin (HelioProgress) and a giomer (Beautifil II). For each material, the specimens were randomly divided into three groups (n=20). Group 1: no prophylaxis treatment (control); Group 2: prophylaxis with pumice and rubber cup; Group 3: prophyl…

Rubber CupPost hocbiologySurface PropertiesAtomic force microscopybusiness.industryComposite numberDentistryHelioprogress:CIENCIAS MÉDICAS [UNESCO]biology.organism_classificationComposite ResinsStreptococcus mutansBacterial AdhesionStreptococcus mutansOtorhinolaryngologyGlass Ionomer CementsUNESCO::CIENCIAS MÉDICASRestorative materialMicroscopy Electron ScanningMedicineSurgerybusinessGeneral DentistryPlaque inflammationMedicina Oral Patología Oral y Cirugia Bucal
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Efficacy of chlorhexidine, hydrogen peroxide and tulsi extract mouthwash in reducing halitosis using spectrophotometric analysis : a randomized contr…

2019

Background To evaluate the efficacy of tulsi extract mouthrinse in reducing halitosis as compared to chlorhexidine and hydrogen peroxide mouthrinses using spectrophotometric analysis. Material and methods It was a parallel, single center, double blinded randomized controlled trial of 15 days duration. A total of 300 participants were screened, out of which 45 subjects those fulfilled inclusion criteria of age range 17-35 years were included in the trial. The participants were randomly provided with tulsi, hydrogen peroxide or chlorhexidine mouthwashes (control group) to use 10 ml twice daily for 15 days. Clinical measurements were taken at baseline and 15 days using arbitrary 0-5 scale for …

SalivaPlaque indexCost effectiveness0211 other engineering and technologiesDentistry02 engineering and technologylaw.invention03 medical and health scienceschemistry.chemical_compoundGingivitis0302 clinical medicineRandomized controlled triallaw021105 building & constructionMedicineHydrogen peroxideGeneral Dentistrybusiness.industryResearchChlorhexidine030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Community and Preventive DentistryGingival indexchemistryUNESCO::CIENCIAS MÉDICASmedicine.symptombusinessmedicine.drug
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The GLP-1 Receptor Agonist Liraglutide Attenuates Atherosclerotic Lesion Development and Potentially Enhances Plaque Stability in an ApoE–/–Mouse Mod…

2013

Settore MED/09 - Medicina InternaAtherosclerosis liraglutide plaque mouseSettore MED/49 - Scienze Tecniche Dietetiche ApplicateSettore MED/13 - Endocrinologia
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Lipoprotein-associated phospholipase A2 activity is increased in patients with definite familial hypercholesterolemia compared with other forms of hy…

2018

Background and Aim: Lipoprotein-associated phospholipase A2(Lp-PLA2) plays a key role in atherosclerosis development. It is considered a marker of increased risk of cardiovascular disease (CVD) and plaque vulnerability. Familial hypercholesterolemia (FH) is a genetic disorder characterized by elevated plasma levels of low-density lipoprotein cholesterol and a higher prevalence of early CVD. Our aim was to evaluate the differences in Lp-PLA2activity in a population of hypercholesterolemic patients with and without definite FH. Methods and Results: Hypercholesterolemic patients were consecutively recruited. Definite FH was defined according to Dutch Lipid Clinic Network criteria ≥8. All pat…

Settore MED/09 - Medicina InternaStatin treatmentEndocrinology Diabetes and MetabolismFamilial hypercholesterolemiaNutrition and DieteticMedicine (miscellaneous)Low density lipoproteinCardiovascular diseaseCardiovascular riskLipoprotein-associated phospholipase A2Plaque vulnerabilityCardiology and Cardiovascular MedicineVascular inflammation
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Gingivitis

2012

Gingival inflammation is caused by bacterial plaque (dental biofilm) that accumulates daily on the teeth. Results in redness, slight swelling, or "puffiness" of the gums and bleeding on tooth brushing. Treatment involves thorough professional tooth cleaning and effective daily removal of dental plaque by tooth brushing and cleaning between the teeth. Necrotizing ulcerative gingivitis (NUG) is a more serious condition that is mainly found in developing countries associated with people with severe malnutrition or HIV/AIDS with low CD4 T-cell counts.

Settore MED/28 - Malattie OdontostomatologicheSettore MED/50 - Scienze Tecniche Mediche ApplicateGingivitis dental plaque systemic diseases
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Gingivitis

2010

Gingival inflammation is caused by bacterial plaque (dental biofilm) that accumulates daily on the teeth. Results in redness, slight swelling, or "puffiness" of the gums and bleeding on tooth brushing. Treatment involves thorough professional tooth cleaning and effective daily removal of dental plaque by tooth brushing and cleaning between the teeth. Necrotizing ulcerative gingivitis (NUG) is a more serious condition that is mainly found in developing countries associated with people with severe malnutrition or HIV/AIDS with low CD4 T-cell counts.

Settore MED/28 - Malattie OdontostomatologicheSettore MED/50 - Scienze Tecniche Mediche ApplicateGingivitis dental plaque systemic diseases
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Gingivitis

2013

Gingival inflammation is caused by bacterial plaque (dental biofilm) that accumulates daily on the teeth. Results in redness, slight swelling, or "puffiness" of the gums and bleeding on tooth brushing. Treatment involves thorough professional tooth cleaning and effective daily removal of dental plaque by tooth brushing and cleaning between the teeth. Necrotizing ulcerative gingivitis (NUG) is a more serious condition that is mainly found in developing countries associated with people with severe malnutrition or HIV/AIDS with low CD4 T-cell counts.

Settore MED/28 - Malattie OdontostomatologicheSettore MED/50 - Scienze Tecniche Mediche ApplicateGingivitis dental plaque systemic diseases
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Gingivitis

2011

Gingival inflammation is caused by bacterial plaque (dental biofilm) that accumulates daily on the teeth. Results in redness, slight swelling, or "puffiness" of the gums and bleeding on tooth brushing. Treatment involves thorough professional tooth cleaning and effective daily removal of dental plaque by tooth brushing and cleaning between the teeth. Necrotizing ulcerative gingivitis (NUG) is a more serious condition that is mainly found in developing countries associated with people with severe malnutrition or HIV/AIDS with low CD4 T-cell counts.

Settore MED/28 - Malattie OdontostomatologicheSettore MED/50 - Scienze Tecniche Mediche ApplicateGingivitis dental plaque systemic diseases
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The effects of two essential oil mouthrinses on supragingival plaque regrowth: a comparative study

2012

Aim: The aim of the study was to investigate the plaque inhibiting effects of two commercially available mouthrinses containing essential oils (EO): Listerine (Johnson & Johnson Consumer Healthcare, S. Palomba-Pomezia, I) and Curasept Daycare (Curaden Healthcare, Saronno, I). Both products contain the same concentration of EO, but Curasept Daycare does not contain ethanol as a solvent. Material and Methods: The study was a single-center, observermasked, cross-over design with 12 subjects randomly allocated to treatment sequence according to three replicates of a 4x4 Latin square, incorporating balance for any carryover. A 0.12% chlorhexidine (CHX) rinse and a saline solution served as posit…

Settore MED/28 - Malattie Odontostomatologichedental plaque mouthrinses essential oils ethanol
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