Search results for "Plaque"
showing 10 items of 334 documents
Techniques d'études de la formation des biofilms. Retour d'expérience issu du domaine "agro-alimentaire" et du domaine "environnemental"
2008
No abstract
Lesquin (Nord), ZAC du Mélantois, Au Chemin Perdu : la nécropole mérovingienne du hameau de Merchin (zone 2) (fin Ve siècle-début VIIIe siècle) : rap…
2015
La construction d'un complexe d'entreprises au hameau de Merchin, au sein d'une zone sensible de découvertes archéologiques, a motivé plusieurs prescriptions de fouille qui se sont déroulées entre l'été 2008 et l'été 2009. Elles ont porté sur un ensemble de structures néolithiques, sur un complexe à vocation agro-pastoral protohistorique/antique, et, enfin, sur une nécropole du premier Moyen Âge. Inscrite dans un terroir occupé de manière plus ou moins continue depuis le Hallstatt jusqu'au bas Moyen Âge, la nécropole mérovingienne de Lesquin est localisée sur la frange orientale du plateau du Mélantois. Elle supplante une occupation débutée au Hallstatt au travers de l'élément structurant l…
La Ortopantomografía como método para la detección de las placas de ateroma calcificadas: Revisión de la literatura
2006
Los accidentes cerebrovasculares (ACV) constituyen la tercera causa de muerte en los países industrializados, tras la cardiopatía isquémica y el cáncer. Se trata pues de un importante problema de Salud pública, no sólo por su elevada incidencia, sino también por el alto costo que genera la rehabilitación física y psicológica de estos pacientes. El Odontoestomatólogo, como profesional de la salud, debe implicarse ante esta situación y contribuir, dentro de sus posibilidades, a la detección precoz de los pacientes con riesgo de sufrir un ACV. Desde la década de los ochenta, distintos autores han descrito la posibilidad de detectar las placas de ateroma calcificadas localizadas en la bifurcaci…
Expression of inflammation-related genes in human atherosclerotic plaques
2010
Aims: Atherosclerosis is an inflammator y disease which molecular mechanisms are not been completely investigated. Our aim is to perform a wide expression study of inflammation related genes in human atherosclerotic plaques. Methods: The Human Inflammation Array (Applied Biosystems) was used to perform the mRNA quantification of 92 inflammation-related genes in 12 atherosclerotic plaques, their respective adjacent regions (with a lower grade lesion) and 7 healthy ar teries. The principle of the array is the real-time PCR amplification with a TaqMan probe specific for each gene. Data analysis was performed with SDS 2.3 software with the comparative Ct method using the gene beta-2-microglobulin as h…
The Role of the anti-amyloidogenic secretase ADAM10 in shedding the APP-like proteins.
2011
ADAM10 (A disintegrin and metalloproteinase 10) has been demonstrated as an enzyme with protective properties in Alzheimer's disease: in mouse models it not only lowered generation of toxic A-beta peptides and formation of senile plaques but also alleviated learning deficits and enhanced synaptic density. This is due to cleavage of the amyloid precursor protein (APP) within its A-beta stretch and to the release of the extracellular domain of APP with neuroprotective function. Aside from cleaving APP, ADAM10 has been linked to over 40 putative substrates at least in cell culture. These substrates are connected with important cellular functions such as cell migration, stress response and tran…
Valoración de la regeneración ósea en un modelo animal: Utilización del plasma rico en plaquetas en la curación de los defectos óseos. Estudio prelim…
2007
INTRODUCCIÓN: Los factores de crecimiento y otras moléculas con capacidad osteoinductora pueden considerarse biomateriales que poseen actividad importante en los procesos de reparación y regeneración de los seres vivos. Esta capacidad puede utilizarse para favorecer, asegurar y aumentar lo procesos de reparación del tejido óseo. En esta tesis doctoral se realiza el estudio de la aplicación aislada en un defecto óseo, de un compuesto rico en plaquetas y factores de crecimiento, el plasma rico en plaquetas (PRP).MATERIAL Y MÉTODO: Hemos realizado un estudio experimental prospectivo, comparativo bilateral y controlado, interviniendo quirúrgicamente 30 conejos raza Nueva Zelanda, a los que se p…
EFFECT OF IMAGE NORMALIZATION ON CAROTID PLAQUE CLASSIFICATION AND THE RISK OF IPSILATERAL HEMISFERIC ISCHEMIC EVENTS. RESULTS FROM THE ASYMPTOMATIC …
2005
The aim of this study was to determine the effect of image normalization on plaque classification and the risk of ipsilateral ischemic neurologic events in patients with asymptomatic carotid stenosis. The first 1,115 patients recruited to the Asymptomatic Carotid Stenosis and Risk of Stroke (ACSRS) study with a follow-up of 6 to 84 months (mean 37.1 months) were included in this study. Duplex ultrasonography was used for grading the degree of internal carotid artery stenosis and for plaque characterization (types 1-5), which was performed before and after image normalization. One hundred sixteen ipsilateral ischemic hemispheric events occurred. Image normalization resulted in 60% of plaques…
Association of carotid atherosclerosis with coronary artery disease: comparison between carotid ultrasonography and coronary angiography in patients …
2012
Les plaques-boucles mérovingiennes ornées d'une croix encadrée par deux griffons : à propos d'une découverte faite à Fleurey-sur-Ouche (Côte-d'Or)
2010
The presentation of this copper alloy belt buckle decorated with a cross flanked by two griffons from Fleurey-sur- Ouche (Côte-d'Or), gives us the opportunity to review our knowledge of this type of buckle, the corpus of which has been recently enriched by new examples. Even though the fifteen known pieces can be categorized in the group D defined by the characteristic finds of the Burgundian kingdom, the iconographical theme remains quite diverse. Also, discoveries have been made all over this vast area, underlining the existence of several workshops, not only in the Jura put also in the Lauragais area.
Sildenafil inhibits the proliferation of cultured human endothelial cells.
2013
The proliferation of endothelial cells plays a crucial role in the development of intraplaque angiogenesis (IPA). IPA is a major source of intraplaque hemorrhage and therefore contributes to the destabilization of atherosclerotic plaques. Therefore, the aim of the present study was to examine, whether sildenafil inhibits endothelial cell growth. The proliferation of human endothelial cells derived from umbilical cord veins (HUVEC) was examined on DNA level by measurements of (3H)-thymidine incorporation. Cell viability was analyzed using trypan blue staining. The proliferation of cultured human endothelial cells was significantly decreased by 1 μmol/l (-48.4%) and 10 μmol/l (-89.6%) sildena…