Search results for "Plasma Volume"

showing 2 items of 12 documents

Rapid hemodilution induced by desmopressin after erythropoietin administration in humans

2011

We have shown that treatment with desmopressin has a very effective hemodilution effect in healthy humans. These results led us to suggest the possible role of desmopressin to mask blood doping in sports. Based on our results, the World Anti-Doping Agency included the desmopressin in the 2011 List of Prohibited Substances and Methods. On this occasion, the aim of our study was to test the desmopressin-induced hemodilution after rHuEpo administration in humans. This was an intra-subject, crossover study in which five physically active males acted as their own controls. A basal blood sample was taken on their first visit to the laboratory. The next day, the subjects began the treatment. They …

medicine.medical_specialtyReticulocytesPLASMA VOLUME EXPANDERS[SDV]Life Sciences [q-bio]Physical Therapy Sports Therapy and RehabilitationHematocrit01 natural sciences03 medical and health sciences0302 clinical medicineBlood dopingInternal medicinemedicineEducación Física y DeportivaHaematocritHemoglobinSTIMULATION INDEXlcsh:Sports medicineDesmopressinHEMOGLOBINmedicine.diagnostic_testbusiness.industry010401 analytical chemistryPlasma volume expanders030229 sport sciencesCrossover study3. Good health0104 chemical sciencesStimulation index and plasma volume expandersEndocrinologyBasal (medicine)HematocritErythropoietinAnesthesiaHemoglobinHEMATOCRITHaemoglobinbusinesslcsh:RC1200-1245hormones hormone substitutes and hormone antagonistsmedicine.drugJournal of Human Sport and Exercise
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Physical activity - an important preanalytical variable

2014

The concentration of several biochemical and hematological biomarkers is strongly influenced by a number of preanalytical variables. Several lines of evidence attest that short, middle, and long-term exercise, as well as the relative intensity of physical effort (from mild to strenuous), may influence a broad array of laboratory variables. The amount of extracellular release and clearance from blood of most of these biomarkers is markedly influenced by the biological characteristics of the molecule(s), level of training, type, intensity and duration of exercise, and time of recovery after training. It is hence noteworthy that test results that fall outside the conventional reference ranges …

medicine.medical_specialtyStrenuous exerciseClinical BiochemistryPhysical activityphysical activityPhysiologyContext (language use)Physical exerciseReviewDiseasepreanalytical variables; exercise; physical activitypreanalytical variablesbiomarkers; training; plasma volume; metabolism; cellular damagecellular damageHumansMedicineDiagnostic ErrorsPlasma VolumetrainingexercisebiologyRelative intensityAthletesbusiness.industryBiochemistry (medical)biomarkersbiology.organism_classificationPhysical therapyNarrative reviewbusinessmetabolismBlood Chemical AnalysisBiochemia Medica
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