Search results for "Plate"

showing 10 items of 1689 documents

Evolving Risk Factors for Mortality after Lung Transplantation over the Last 10 Years: Insights from a Single-Centre Database

2016

s S233 218 (82%) patients received pooled platelet transfusion -median (IQR) 1(1-2) U. 209 (79%) and 129 (49%) patients received fresh frozen plasma (FFP) and cryoprecipitate with a median (IQR) of 3(2-4) and 0(0-0) U respectively. Conclusion: Rate and volume of transfusion of blood products compare favourably with centres performing surgery off CPB or on ECMO. Requirement for ECMO particularly for BTT, but also PGD is associated with high transfusion requirements.

Pulmonary and Respiratory MedicineTransplantationmedicine.medical_specialtybusiness.industrymedicine.medical_treatmentSurgerySingle centresurgical procedures operativePlatelet transfusionCryoprecipitatemedicineLung transplantationSurgeryFresh frozen plasmaCardiology and Cardiovascular MedicinebusinessIntensive care medicineThe Journal of Heart and Lung Transplantation
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185 * RED BLOOD CELL DISTRIBUTION WIDTH PREDICTS MORBIDITY AND MORTALITY AFTER AORTIC VALVE REPLACEMENT

2014

Pulmonary and Respiratory Medicinemedicine.medical_specialtyrenal failuremedicine.medical_treatmentcardiovascular disease red distribution width aortic valve replacement prolonged ventilation renal failurered distribution widthPreoperative careBlood cellchemistry.chemical_compoundAortic valve replacementcardiovascular diseaseInternal medicineMedicineDistribution (pharmacology)Plateletaortic valve replacementRenal replacement therapyCreatininebusiness.industrySettore MED/23 - Chirurgia Cardiacamedicine.diseaseSurgerymedicine.anatomical_structurechemistryprolonged ventilationCardiologySurgeryUnderweightmedicine.symptomCardiology and Cardiovascular Medicinebusiness
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Role of JAK/STAT in Interstitial Lung Diseases; Molecular and Cellular Mechanisms

2021

Interstitial lung diseases (ILDs) comprise different fibrotic lung disorders characterized by cellular proliferation, interstitial inflammation, and fibrosis. The JAK/STAT molecular pathway is activated under the interaction of a broad number of profibrotic/pro-inflammatory cytokines, such as IL-6, IL-11, and IL-13, among others, which are increased in different ILDs. Similarly, several growth factors over-expressed in ILDs, such as platelet-derived growth factor (PDGF), transforming growth factor β1 (TGF-β1), and fibroblast growth factor (FGF) activate JAK/STAT by canonical or non-canonical pathways, which indicates a predominant role of JAK/STAT in ILDs. Between the different JAK/STAT iso…

QH301-705.5medicine.medical_treatmentReviewCatalysisstatInorganic ChemistryPulmonary fibrosismedicineHumansProtein IsoformsPhysical and Theoretical ChemistryBiology (General)STAT3Molecular BiologyProtein Kinase InhibitorsQD1-999SpectroscopyCellular SenescenceJanus KinasesbiologyChemistryGrowth factorInterleukinsinterstitial lung disease (ILD)Organic ChemistryJAK-STAT signaling pathwayGeneral Medicinerespiratory systemmedicine.diseaseEndoplasmic Reticulum StressComputer Science Applicationsrespiratory tract diseasesSTAT Transcription FactorsChemistrysignal transducer and activator of transcription (STAT)biology.proteinCancer researchidiopathic pulmonary fibrosis (IPF)Janus kinaseLung Diseases InterstitialJanus kinases (JAK)Platelet-derived growth factor receptorTransforming growth factorSignal TransductionInternational Journal of Molecular Sciences
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Analytical and Numerical Investigation of 3D Multilayer Detachment Folding

2013

Multilayer detachment folding, in which a sequence of sedimentary layers is compressed above a weaker salt layer, is a common mode of deformation in thin-skinned fold-and-thrust belts. Here, we investigate the dynamics of multilayer detachment folding with three different viscosities: lower detachment or salt layer, overlying weak layers and competent layers. A semi-analytical solution, based on thick plate analysis of multilayer systems, is used to create mechanical phase diagrams of folding dominant wavelength and growth rate as a function of material parameters. The validity of the phase diagrams is tested and confirmed beyond the nucleation stages of folding by performing several 2D and…

Quantitative Biology::BiomoleculesMaterials science010504 meteorology & atmospheric sciencesDeformation (mechanics)NucleationNumerical modelingGeometry010502 geochemistry & geophysics01 natural sciencesFolding (chemistry)Thick plateGrowth rateLayer (electronics)0105 earth and related environmental sciencesPhase diagramMathematics of Planet Earth
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Structural and conformational dynamics of supercooled polymer melts: Insights from first-principles theory and simulations

2007

We report on quantitative comparisons between simulation results of a bead-spring model and mode-coupling theory calculations for the structural and conformational dynamics of a supercooled, unentangled polymer melt. We find semiquantitative agreement between simulation and theory, except for processes that occur on intermediate length scales between the compressibility plateau and the amorphous halo of the static structure factor. Our results suggest that the onset of slow relaxation in a glass-forming melt can be described in terms of monomer-caging supplemented by chain connectivity. Furthermore, a unified atomistic description of glassy arrest and of conformational fluctuations that (as…

Quantitative Biology::BiomoleculesMaterials scienceThermodynamicsFOS: Physical sciences02 engineering and technologyCondensed Matter - Soft Condensed Matter021001 nanoscience & nanotechnologyPlateau (mathematics)01 natural sciencesAmorphous solidCondensed Matter::Soft Condensed Matterchemistry.chemical_compoundMonomerchemistry0103 physical sciencesCompressibilityRelaxation (physics)Soft Condensed Matter (cond-mat.soft)Halo010306 general physics0210 nano-technologySupercoolingStructure factor[PHYS.COND.CM-SCM]Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft]ComputingMilieux_MISCELLANEOUS
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Seismic stratigraphy of the north-westernmost area of the Malta Plateau (Sicily Channel): The Middle Pleistocene-Holocene sedimentation in a tidally …

2022

In this study we present the results of a seismic-stratigraphic analysis of sub-bottom profiles in the north-westernmost area of the Malta Plateau in order to define the depositional mechanisms for the upper Quaternary sequences. During this interval the morphology of the Malta Plateau was characterized by a ramp and bathymetries not exceeding 200 m. Two major unconformities, related to MIS 6 and MIS 2 (the latter corresponding to the Last Glacial Maximum, LGM), characterize the upper Quaternary sequences. The geometries of the recognized seismic units indicate as depositional mechanisms were controlled by subsidence and sea-level fluctuations. In detail, deposits related to the last glacia…

QuaternaryGeochemistry and PetrologySand sheetSand sheet; Infralittoral prograding wedge; Bedforms; Coastal dune system; Malta Plateau; QuaternaryGeologyCoastal dune systemBedforms Coastal dune system Infralittoral prograding wedge Malta Plateau Quaternary Sand sheetOceanographyBedformsMalta PlateauInfralittoral prograding wedge
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On the Nature of the Plateau in Two-Step Dinuclear Spin-Crossover Complexes

2004

A remarkable feature of the spin-crossover process in several dinuclear iron(II) compounds is a plateau in the two-step transition curve. Up to now, it has not been possible to analyse the spin state of dinuclear pairs that constitute such a plateau, due to the relative high temperatures at which the transition takes place in complexes investigated so far. We solved this problem by experimentally studying a novel dinuclear spin-crossover compound [[Fe(phdia)(NCS)(2)](2)(phdia)] (phdia: 4,7-phenanthroline-5,6-diamine). We report here on the synthesis and characterisation of this system, which exhibits a two-step spin transition at T(c1)=108 K and T(c2)=80 K, displaying 2 K and 7 K wide therm…

QuenchingSpin statesChemistryOrganic ChemistrySpin transitionGeneral ChemistryPlateau (mathematics)CatalysisCrystallographyNuclear magnetic resonanceSpin crossoverMetastabilityMössbauer spectroscopySpin-½
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A Rayleigh-Ritz approach for postbuckling analysis of variable angle tow composite stiffened panels

2018

Abstract A Rayleigh-Ritz solution approach for generally restrained multilayered variable angle tow stiffened plates in postbuckling regime is presented. The plate model is based on the first order shear deformation theory and accounts for geometrical nonlinearity through the von Karman’s assumptions. Stiffened plates are modelled as assembly of plate-like elements and penalty techniques are used to join the elements in the assembled structure and to apply the kinematical boundary conditions. General symmetric and unsymmetric stacking sequences are considered and Legendre orthogonal polynomials are employed to build the trial functions. A computer code was developed to implement the propose…

Rayleigh–Ritz methodEngineeringSource codemedia_common.quotation_subjectComposite numberStructure (category theory)02 engineering and technologyPhysics::Fluid Dynamics0203 mechanical engineeringGeneral Materials ScienceBoundary value problemSettore ING-IND/04 - Costruzioni E Strutture AerospazialiVariable angle tow composites Composite stiffened plates Postbuckling analysis Rayleigh-Ritz method First Order Shear DeformationLegendre polynomialsCivil and Structural Engineeringmedia_commonbusiness.industryMechanical EngineeringStructural engineering021001 nanoscience & nanotechnologyFinite element methodComputer Science Applications020303 mechanical engineering & transportsModeling and SimulationOrthogonal polynomials0210 nano-technologybusinessComputers & Structures
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Post-buckling analysis of cracked multilayered composite plates by pb-2 Rayleigh–Ritz method

2015

Abstract A pb-2 Rayleigh–Ritz variational approach for the analysis of post-buckling behavior of cracked composite plates is presented. The plate is modeled by the first order shear deformation theory taking geometric nonlinearities into account through the von Karman’s theory. General stacking sequences are considered. Cracks are modeled by using subdomain decomposition of the plate coupled with penalty techniques, used to augment the variational statement with the needed continuity conditions along the connected subdomains edges. Numerical procedures have been developed and used to validate the present solution by comparison with available literature results. Original results are then pre…

Rayleigh–Ritz methodEngineeringbusiness.industryShear deformation theoryComposite numberStackingStructural engineeringComposite plateFirst order shear deformation theory (FSDT)First orderCracked platePb2 Ritz methodPhysics::Fluid DynamicsPost-buckling analysiBucklingCeramics and CompositesSettore ING-IND/04 - Costruzioni E Strutture AerospazialibusinessCivil and Structural EngineeringComposite Structures
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Post-Buckling Analysis of Damaged Multilayered Composite Stiffened Plates by Rayleigh-Ritz Method

2016

A Rayleigh-Ritz approach for the analysis of buckling and post-buckling behavior of cracked composite stiffened plates is presented. The structure is modeled as the assembly of plate elements modeled by the first order shear deformation theory and taking geometric nonlinearities into account through the von Karman’s theory assumptions. Continuity along the plate elements connected edges and the enforcement of rigid and elastic restraints of the plate boundaries are obtained by using penalty techniques, which also allow to straightforwardly implement efficient crack modeling strategies. General symmetric and unsymmetric stacking sequences are considered and numerical procedures have been dev…

Rayleigh–Ritz methodcomposite plates cracked plates post-buckling analysis Ritz method first order shear deformation theory (FSDT)Materials sciencebusiness.industryShear deformation theoryComposite numberStacking02 engineering and technologyGeneral MedicineStructural engineeringFirst order01 natural sciencesFinite element methodRitz methodPhysics::Fluid Dynamics010101 applied mathematics020303 mechanical engineering & transports0203 mechanical engineeringBuckling0101 mathematicsbusinessSettore ING-IND/04 - Costruzioni E Strutture Aerospaziali
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