Search results for "Plate"

Steady state thermo-mechanical analysis of the IFMIF Lithium target system with bayonet backplate under design conditions

2014

Enhanced Lipid Peroxidation and Platelet Activation in the Early Phase of Type 1 Diabetes Mellitus

2003

Background— To investigate early events possibly related to the development of diabetic angiopathy, we examined whether 8-iso-prostaglandin F 2α (8-iso-PGF 2α ) formation, a marker of in vivo oxidant stress, is altered in different stages of type 1 diabetes (T1DM) and whether it correlates with the rate of thromboxane (TX) A 2 biosynthesis, a marker of in vivo platelet activation. We also investigated the relationship between inflammatory markers and F 2 -isoprostane formation in this setting. Methods and Results— A cross-sectional study was performed in 23 insulin-treated patients aged <18 years with new-onset T1DM (≤6 weeks, group A), matched for age and gender with 23 patients with s…

Flow and Heat Transfer in Corrugated Passages: Direct and Large-Eddy Simulation and Comparison with Experimental Results

1993

Complex pluri-fragmentary fractures of the distal humerus: our experience with double-plate

2011

Stress and strain distribution in perforated plate loaded in median plane

2019

Managerial career plateaue : determinants, consequences and coping strategies

2008

Masteroppgave i økonomi og administrasjon - Universitetet i Agder 2008 During last decade managers who were practicing in different industries in Sri Lanka, have struggled with having less promotional opportunities. This initially leads them to become plateaued with their career. This study applied the theory from career management literature to examine factors significantly influenced to employees’ perception of being subjectively plateaued and objectively plateaued. Additionally, this study aims to identify the relationship between career plateauing and its implication toward job satisfaction, organizational commitment, intention to quit and job induced stress. Further, coping strategies …

Influence of geometric variations on LV activation times: A study on an atlas-based virtual population

2010

We present the fully automated pipeline we have developed to obtain electrophysiological simulations of the heart on a large atlas-based virtual population. This virtual population was generated from a statistical model of left ventricular geometry, represented by a surface model. Correspondence between tetrahedralized volumetric meshes was obtained using Thin Plate Spline warps. Simulations are based on the fast solving of Eikonal equations, and stimulation sites correspond to physiological activation. We report variations of total activation time introduced by geometry, as well as variations in the location of last activation. The obtained results suggest that the total activation time ha…

Sensitivity analysis of mesh warping and subsampling strategies for generating large scale electrophysiological simulation data

2011

The analysis of large-scale simulation data from virtual populations can be effective to gain computational insight into disease mechanisms and treatment strategies, which can serve for generating hypotheses for and focusing subsequent clinical trials. This can be instrumental in shortening the critical path in medical product development and more cost-effective clinical trials. A previously published pipeline established point correspondence among volumetric meshes to enable meaningful statistics on cardiac electrophysiological simulations on the anatomical distribution of a large-scale virtual population. Thin Plate Splines (TPS), derived from surface deformations, were used to warp a tem…


 Donor Exposures in Recipients of Pooled Platelet Concentrates: a Case-Study in Arithmetic, Logic, "Expert Opinion", and the "Peer Review" Proc…

2013

Advocacy for single-donor (rather than pooled) platelets has been based on the absolute increase in the risk of transfusion-transmitted infections (TTIs) from pooled (rather than single-donor) platelets in the population of platelet transfusion recipients. A recent study published in a prestigious medical journal advocated for pooled (rather than single-donor) platelets based on the relative increase in the risk of TTIs from pooled (rather than single-donor) platelets in patients transfused with any blood component. If this policy recommendation for use of pooled (rather than single-donor) platelets were followed in the US, there would be an annual increase in the risk of TTIs by 15-20 reci…

Micromanipulation Techniques for the Isolation of Single Microorganisms

2005

A prerequisite for the biochemical and physiological investigation of microorganisms is the isolation and management of pure cultures. The only absolute criterion of purity for a bacterial culture is that it has been derived from the progeny of a single cell. Failure to apply this criterion may lead to much effort in proving the purity of a culture. All strains upon which research is to be based should therefore be rigorously purified before starting to investigate the properties of individual organisms (Johnstone 1969). Ecologically oriented microbiologists are faced especially with the problem of how to obtain a pure culture of certain microbial strains from their densely populated natura…