Search results for "Pleurodesis"

2021

BACKGROUND Postoperative air leaks are a common complication after lung surgery. They are associated with prolonged hospital stay, increased postoperative pain and treatment costs. The treatment of prolonged air leaks remains controversial. Several treatments have been proposed including different types of sealants, chemical pleurodesis, or early surgical intervention. The aim of this review was to analyze the impact of autologous blood pleurodesis in a systematic way. METHODS A systematic review of the literature was conducted until July 2020. Studies with more than five adult patients undergoing lung resections were included. Studies in patients receiving blood pleurodesis for pneumothora…

Matrix metalloproteinases production in malignant pleural effusions after talc pleurodesis

2003

SUMMARY In this study we have evaluated the modifications of matrix metalloproteinases (MMPs) in malignant pleural fluids taken from patients suffering from lung cancer and treated with intrapleural talc instillation to induce pleurodesis. Furthermore, we have analysed the variations of some inflammatory mediators (C-reactive protein, α-1 antitrypsin) and of a protein (plasminogen) involved in MMP activation. In all patients the clinical improvement after talc pleurodesis was followed by a reduction in MMP-1, TIMP-1, C-reactive protein, α-1 antitrypsin and plasminogen activity. Furthermore, MMP-9 levels were variable; in fact, in some patients they were high at the beginning of treatment, i…

Video-thoracoscopic surgical pleurodesis in the management of malignant pleural effusion: the importance of an early intervention.

2005

Thoracentesis plays an important role in cancer patients with symptomatic effusions, although its effect is short-lived and symptoms recur in almost all patients. Early video-thoracoscopic surgical pleurodesis may provide added benefit to a group of patients with advanced cancer presenting with symptomatic malignant pleural effusion. Seventy-six patients with advanced cancer and pleural effusion due to pulmonary-pleural metastases were recruited. In 51 cases (67.1%), at least one thoracentesis was performed before admission for surgery. Preoperative staging consisted of chest radiograph, CT scan, and blood gas analysis. The mean Karnofsky performance status was about 50. Pleurodesis with ta…

Resultados de la cirugía videotoracoscópica en el neumotórax espontáneo primario analizando la técnica de pleurodesis por abrasión versus la técnica …

2013

Presentamos en este trabajo nuestra experiencia acumulada en el tratamiento quirúrgico del neumotórax espontáneo primario mediante cirugía videotoracoscópica. Se ha elegido el neumotórax por tratarse de la patología benigna que, además de frecuente, ha sido la primera en beneficiarse de la VATS. Durante un periodo de dieciséis años (entre junio de 1994 y febrero de 2010) se realizaron 238 intervenciones por neumotórax espontáneo primario mediante VATS en 216 pacientes; en 115 procedimientos se escogió la abrasión pleural como método de pleurodesis, mientras que en 123 casos se llevó a cabo una técnica mixta consistente en pleurectomía apical combinada con abrasión del resto de la pleura par…