Search results for "Pool"
showing 10 items of 238 documents
Rheumatoid arthritis affects left ventricular mass: Systematic review and meta-analysis.
2015
Abstract Background Cardiovascular disease represents one of the most important extra-articular causes of morbidity and mortality in patients with rheumatoid arthritis (RA). Evidences showed that several cardiac structures can be affected during the course of the disease as well as abnormalities of left ventricular diastolic filling. Contrasting data are available about left ventricular mass (LVM) involvement in patients asymptomatic for cardiovascular disease. The purpose of this systematic review and meta-analysis is to summarize the effects of RA on LVM in rheumatoid arthritis patients without cardiovascular disease. Methods A systematic research of the current case–control studies was c…
Effects of Morning Versus Evening Statin Administration on Lipid Profile: A Systematic Review and Meta-Analysis
2017
Background Evidence about the optimal time of day at which to administer statins is lacking. Objective The objective of this study is to synthesize evidence about effects of morning vs evening statin administration on lipid profile. Methods We searched PubMed, SCOPUS, Web of Science, and Embase databases (from inception up to July 24, 2016) to identify the relevant studies. Mean differences (MDs) between the change scores in lipid parameters were pooled using a fixed-effect model. Results Eleven articles with 1034 participants were eligible for the analysis. The pooled analysis comparing effects of morning vs evening administration of statins on plasma total cholesterol (TC; P = .10), high…
National level wealth inequality and socioeconomic inequality in adolescent mental wellbeing
2020
Abstract Background Previous research established a positive association between national income inequality and socioeconomic inequalities in adolescent health, but little is known about the extent to which national level inequalities in accumulated financial resources (i.e. wealth) are associated with these health inequalities. Therefore, we examined the association between national wealth inequality and income inequality and socioeconomic inequalities in adolescent mental wellbeing. Methods Data were from 17 countries participating in three successive waves (2010, 2014 and 2018) of the cross-sectional Health Behaviour in School-aged Children (HBSC) study. We combined individual-level data…
Microsurgical Scalp Reconstruction in the Elderly
2015
BACKGROUND Microvascular reconstruction is the mainstay of treatment in complex scalp defects. The rate of elderly patients requiring scalp reconstruction is increasing, but outcomes in elderly patients are unclear. The purpose of this study was to systematically review the literature pertaining to free tissue transfer for scalp reconstruction in patients older than 65 years to compare outcomes among different free flaps and determine the safety profile of treatment. METHODS A systematic review of the available literature of patients undergoing microvascular scalp reconstruction was completed. Details for patients 65 years and older were extracted and reviewed for data analysis. RESULTS A t…
Use of Marginal Donors in Kidney Transplantation: Our Experience
2006
The use of elderly donors has been advocated to expand the organ donor pool because of increased needs and the organ shortage. The aim of this study was to analyze whether the use of elderly donors and marginal kidneys affected the outcome of renal transplantations. Herein we presented data on 126 kidney transplantations performed from January 1996 to September 2003 using 32 marginal donors (group A) and 94 ideal donors (group B). We analyzed the medical and surgical complications and the graft survivals at a median follow-up of 18 months. Medical and surgical complications occurred in 22% and 5% versus 7% and 4% in groups A and B, respectively. The mean cold ischemia time and the mean age …
FRI0189 POOLED ANALYSIS OF THE REAL-WORLD EFFECTIVENESS OF BELIMUMAB IN TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS USING MULTI-COUNTRY DATA FROM THE O…
2019
Background: Real-world evidence of belimumab effectiveness in patients with systemic lupus erythematosus (SLE) has been reported separately for several countries through the OBSErve (evaluation Of use of Belimumab in clinical practice SEttings) programme. Objectives: To evaluate the effectiveness of belimumab in patients with SLE using pooled data from the individual OBSErve studies. Methods: This was a post hoc meta-analysis (GSK study 206351) of patient level data pooled from six retrospective observational cohort studies (Argentina, Canada, Germany, Spain, Switzerland, United States of America). Physicians provided data for adults (≥18 years; clinical diagnosis of SLE) who had initiated …
Cohort profile: Thrombolysis in Ischemic Stroke Patients (TRISP): a multicentre research collaboration
2018
PurposeThe ThRombolysis in Ischemic Stroke Patients (TRISP) collaboration aims to address clinically relevant questions about safety and outcomes of intravenous thrombolysis (IVT) and endovascular thrombectomy. The findings can provide observational information on treatment of patients derived from everyday clinical practice.ParticipantsTRISP is an open, investigator-driven collaborative research initiative of European stroke centres with expertise in treatment with revascularisation therapies and maintenance of hospital-based registries. All participating centres made a commitment to prospectively collect data on consecutive patients with stroke treated with IVT using standardised definiti…
Taxonomy and conservation ofPancratium maritimum(Amaryllidaceae) and relatives in the Central Mediterranean
2015
Pancratium maritimum L. (Amaryllidaceae) is a geophyte occurring in the Mediterranean region, from the Black Sea to part of the Atlantic coast. This plant is receiving much attention from the international scientific community due to its value as a bioindicator, the potential industrial value of its chemical compounds, and its use as a commercial ornamental plant. Plant morphometry and sequences of three plastid DNA regions (rbcL, matK, trnH-psbA) were used to assess the phenotypic and genetic variability of this taxon and its closest congeneric species (in particular Pancratium linosae, from the volcanic island of Linosa) in the Central Mediterranean (Sicily, Tunisia and surrounding island…
Hyper-flexible Convolutional Neural Networks based on Generalized Lehmer and Power Means
2022
Convolutional Neural Network is one of the famous members of the deep learning family of neural network architectures, which is used for many purposes, including image classification. In spite of the wide adoption, such networks are known to be highly tuned to the training data (samples representing a particular problem), and they are poorly reusable to address new problems. One way to change this would be, in addition to trainable weights, to apply trainable parameters of the mathematical functions, which simulate various neural computations within such networks. In this way, we may distinguish between the narrowly focused task-specific parameters (weights) and more generic capability-spec…
Ohjelmistokehittäjän keinoja Java-koodin tehostamiseen ja keinojen hyödyllisyys
2010
Honkanen, Juho Ville-Pekka Ohjelmistokehittäjän keinoja Java-koodin tehostamiseen ja keinojen hyödyllisyys / Ville-Pekka Honkanen Jyväskylä: Jyväskylän yliopisto, 2010. 37 s. Kandidaatintutkielma Tässä tutkielmassa käydään lävitse keinoja, joilla voidaan parantaa Java-koodin suorituskykyä. Tutkielma on toteutettu kirjallisuuskatsauksena ja sen tarkoituksena on tutkia perinteisiä koodioptimointeja ja selvitetään onko niistä enää nykypäivänä hyötyä. Lisäksi käsitellään keinoja, joilla todella voi parantaa ohjelman suorituskykyä ja missä tilanteissa näitä voidaan käyttää. Läpi käydään myös koodaamistapoja, joita tulisi välttää, esimerkiksi lopetusmetodien käyttö. Tutkielmassa selviää, että us…