Search results for "Population"

Chapter 4 3D brainstem topodiagnosis – a voxel-based model analyzing MR imaging data

2006

Publisher Summary This chapter presents a new method of statistically based three-dimensional (3D) brainstem mapping to identify brainstem structures responsible for specific clinical and electrophysiological abnormalities. To ensure reliable correlations, a large cohort of patients with magnetic resonance (MR)-documented brainstem infarctions were recruited in two European neurological institutions—namely, the Department of Neurology, Johannes Gutenberg University, Mainz, Germany, and the Department of Neurological Sciences, “La Sapienza” University of Rome, Italy. This method minimizes the risk of highlighting vascular territories rather than the structures specifically responsible for th…

Fibrinogen plasma levels in an apparently healthy general population: Relation to environmental and genetic determinants

1998

SummaryElevated fibrinogen levels are an independent risk factor for cardiovascular ischemic disease. We investigated the relationship between cardiovascular ischemic risk factors, the fibrinogen Bβ-chain G/A-455 polymorphism and plasma fibrinogen levels in 989 apparently healthy subjects. Fibrinogen values were higher in subjects with C reactive protein (C-RP) > 0.33 mg/dl, BMI > 23.9 kg/m2, total cholesterol > 4.84 mmol/l, triglycerides >1.02 mmol/l, PAI-1 antigen >12.2 ng/ml, carriers of the A allele, first-degree relative history of coronary artery disease, or consuming >10 cigarettes per day (p <0.01). Men and ethanol drinkers showed lower plasma fibrinogen levels …

Case Control Study on Childhood Leukemia in Lower Saxony, Germany

1996

In two municipalities in Lower Saxony statistically valid clusters were observed, which attracted great public interest. Committees were set up to initiate a large variety of on-the-spot-investigations. Finally, it was decided to conduct a case control study throughout Lower Saxony to explore potential risk factors which might explain the observed clusters. A limited number of already established and currently discussed hypotheses was chosen for investigation. The study was based on patients registrated at the German Children's Cancer Registry (GCCR). For each child with leukemia diseased between 1988 and 1993 two population-based controls (local and state controls) and one tumour control w…

SP1-5 Endocrine, nutritional and metabolic diseases as associated causes of death in older women in Rio de Janeiro, Brazil

2011

Introduction Changes in lifestyle contributed to an increased incidence and mortality from endocrine, nutritional and metabolic diseases in developing countries. The aim of this study was to evaluate the burden of these diseases as a cause of death in older women in a Brazilian city. Methods All deaths of women aged 70 years or older, occurring in Rio de Janeiro, between 2003 and 2006, were identified in the Mortality Information System, a population-based nationwide registry. Death certificates with an ICD 10 Chapter IV code (E00-E90) were selected. When the code corresponded to the underlying cause, its subgroup was determined (endocrine, nutritional or metabolic diseases) and the associa…

PO-0994 Ltri In Paediatrics: Analysis Of An Annual Survey

2014

Background and aims Lower tract respiratory infections (LTRI) are very frequent in paediatric population. We collected epidemiological, etiological and clinical data and correlated them to some variables. Methods We performed an observational study of all children with a LTRI, admitted to our Paediatric Unit from February 2013 to January 2014. The population was grouped in three classes of ages (0–2yr, 3–6yr, >6yr). All patients underwent to a questionnaire focused on exposition to protective and risk factors for respiratory diseases. Results 83 children were included. We grouped them according to discharge diagnosis and analysed the distribution for ages, sex and season of onset. At the ad…

Prevalence of lumbosacral radiculopathy in two Sicilian municipalities

2009

Objectives - As part of a door-to-door survey of neurologic diseases, we investigated the prevalence of lumbosacral radiculopathy (LR) in two Sicilian municipalities (N = 14,540, as of November 1, 1987). Material & methods - During phase 1, we administered a brief screening instrument to subjects in the study population. In phase 2, study neurologists using specified diagnostic criteria investigated those subjects who screened positive. Our case finding was restricted to subjects who manifested symptoms of LR in the six months preceding the prevalence day. Results - We found 143 subjects affected by LR (112 definite, 31 possible) yielding a crude prevalence of 9.8 cases per 1,000 population…

New Technique in Tendon Sport Recovery. Percutaneous Electrolysis Intratissue (EPI®)

2013

Based on the literature and clinical experience we know that the technique of percutaneous electrolysis intratissue (EPI ® ) has positive effects on the recovery of human tendinopathies. The application of the technique, together with the completion of eccentric exercise, give benefits leading to anatomical and functional recovery in the tendon that can be appreciated by ultrasound using the scale of "Victorian Institute of Sport Assessment-patellar tendon" (VISA-P). Due to clinical knowledge, damage to tendon is accompanied by increase in oxidative stress, cell death and inflammation at the damaged area. The EPI ® technique produced a galvanic current inside the tendon, with an acupuncture…

Exercise effects on cardiovascular disease: from basic aspects to clinical evidence.

2021

Contains fulltext : 283453.pdf (Publisher’s version ) (Closed access) Cardiovascular (CV) disease (CVD) remains the leading cause of major morbidity and CVD- and all-cause mortality in most of the world. It is now clear that regular physical activity (PA) and exercise training (ET) induces a wide range of direct and indirect physiologic adaptations and pleiotropic benefits for human general and CV health. Generally, higher levels of PA, ET, and cardiorespiratory fitness (CRF) are correlated with reduced risk of CVD, including myocardial infarction, CVD-related death, and all-cause mortality. Although exact details regarding the ideal doses of ET, including resistance and, especially, aerobi…

Comparison of the roles of common constitutional and behavioural parameters in back performance estimates

2006

Objective: To compare the associations between different physical activity histories and anthropometric measures in isokinetic lifting performance, isometric back extension endurance and psychophysical lifting tests. Background: The relative roles and interaction of these factors related to back function are largely unknown. Methods: The subjects consisted of a population-based sample of 210 working-age males. Paraspinal muscle cross-sectional areas were obtained by magnetic resonance imaging; anthropometric measures, isokinetic and psychophysical lifting capacity, and isometric back extension endurance tests were performed and current and physical activity histories and occupational loadin…

2015

Low prevalence of substance-use disorder has been reported in adults with autism. However, on a superficial level, adults with high-functioning autism (HFA) display a ‘normal’ facade when they drink alcohol, which may explain why their alcohol dependency is not better diagnosed. Here, we report two cases of HFA adults who use alcohol and psychostimulants to cope with their anxiety and improve their cognitive abilities and social skills. We analyze how neurocognitive traits associated with HFA may be potential triggers for substance-use disorder. Better identification of autism and its cognitive impairments, which may be vulnerability traits for developing substance-use disorders, could help…