Search results for "Porte"

showing 10 items of 1894 documents

The cytoplasmic PASC domain of the sensor kinase DcuS of Escherichia coli : role in signal transduction, dimer formation, and DctA interaction

2013

The cytoplasmic PAS(C) domain of the fumarate responsive sensor kinase DcuS of Escherichia coli links the transmembrane to the kinase domain. PAS(C) is also required for interaction with the transporter DctA serving as a cosensor of DcuS. Earlier studies suggested that PAS(C) functions as a hinge and transmits the signal to the kinase. Reorganizing the PAS(C) dimer interaction and, independently, removal of DctA, converts DcuS to the constitutive ON state (active without fumarate stimulation). ON mutants were categorized with respect to these two biophysical interactions and the functional state of DcuS: type I-ON mutations grossly reorganize the homodimer, and decrease interaction with Dct…

PAS domainDicarboxylic Acid TransportersModels MolecularfumarateProtein ConformationEscherichia coli ProteinsDNA Mutational AnalysisDctAModels Biological570 Life sciencessignal transduction.Escherichia coliProtein Interaction Domains and MotifsProtein MultimerizationDcuS sensor kinaseProtein KinasesOriginal ResearchSignal Transduction570 Biowissenschaften
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The stability and functional properties of proteoliposomes mixed with dextran derivatives bearing hydrophobic anchor groups

1992

Liposomes composed of Escherichia coli phospholipid were coated with polysaccharides bearing hydrophobic palmitoyl anchors. The effect on the stability of liposomes without or with integral membrane proteins was investigated. A high concentration of hydrophobized dextrans protected the liposomes against detergent degradation, decreased the fluidity of the membranes, prevented fusion of the liposomes and enhanced their stability. Proteoliposomes containing beef heart cytochrome-c oxidase and the lactose transport carrier of E. coli were similarly affected by coating with the dextrans. Under these conditions both membrane proteins were still active. Long-term stability of the coated liposomes…

PROTEINMembrane FusionBiochemistryMembrane Potentialschemistry.chemical_compoundFUSIONINTEGRAL MEMBRANE PROTEINBINDINGIntegral membrane proteinLiposomeSymportersEscherichia coli ProteinsVesiclePROTEOLIPOSOMEDextransDEXTRAN DERIVATIVEBIOLOGICAL-MEMBRANESFluoresceinsMembraneCarbohydrate SequenceESCHERICHIA-COLIMonosaccharide Transport ProteinsCations DivalentMembrane FluidityProteolipidsMolecular Sequence DataBiophysicsPhospholipidFluorescence PolarizationLactose transportOXIDASECYTOCHROME-CVESICLESElectron Transport Complex IVHYDROPHOBIC ANCHOR GROUPEscherichia coliAnimalsKINETICSChromatographyMyocardiumMembrane ProteinsMembrane Transport ProteinsBiological membraneCell BiologyPROTON-MOTIVE FORCEMembrane proteinchemistryLiposomesCalciumCattleBiochimica et Biophysica Acta (BBA) - Biomembranes
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Estilos de socialización parental y rendimiento deportivo en adolescentes

2015

Los efectos de la socialización parental en adolescentes fueron analizados en un muestra de 970 participantes de edades comprendidas entre los 13 a 18 años de dos muestras de adolescentes diferentes: no deportistas (786 adolescentes, 52,8% y 47,2% hombres) y deportistas de alto nivel autonómico (184 adolescentes, 48,37% mujeres y 51,63% hombres). El primer paso fue clasificar los según el cuestionario ESPA29 en uno de los cuatro tipos de estilos de socialización parental (autorizativo, autoritario, indulgente y negligente) según la puntuación obtenida en las siguientes dimensiones: Aceptación/Implicación y Severidad/Imposición. Una vez establecido a que grupo pertenecían se analizó si exist…

PSICOLOGIA EVOLUTIVAMETODOLOGIA PSICOLOGICAvaloresautoconceptodeporte de alto nivelsocialización parentalMETODOS EDUCATIVOS
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Multi-Functional Nanogels for Tumor Targeting and Redox-Sensitive Drug and siRNA Delivery

2016

(1) Background: A new family of nanosystems able to discern between normal and tumor cells and to release a therapeutic agent in controlled way were synthetized by e-beam irradiation. This technique permits to obtain biocompatible, sterile, carboxyl-functionalized polyvinylpyrrolidone (PVP-co-acrylic acid) nanogels (NGs); (2) Methods: Here, we performed a targeting strategy based on the recognition of over-expressed proteins on tumor cells, like the folate receptor. The selective targeting was demonstrated by co-culture studies and flow cytometry analysis, using folate conjugated NGs. Moreover, nanoparticles were conjugated to a chemotherapeutic drug or to a pro-apoptotic siRNA through a gl…

PVPPharmaceutical ScienceNanogels02 engineering and technologyPharmacology01 natural sciencesAntioxidantsAnalytical Chemistryfolate-targetingPolyethylene GlycolsNanogelchemistry.chemical_compoundMiceRNA interferenceNeoplasmsDrug DiscoveryFluorescence microscopePolyethyleneimineRNA Small InterferingCytotoxicitymedicine.diagnostic_testPovidone021001 nanoscience & nanotechnologyControlled releaseCell biologyChemistry (miscellaneous)Folate receptorMolecular Medicinee-beamGSH-responsive release0210 nano-technologyOxidation-Reduction010402 general chemistrydoxorubicinArticleFlow cytometryFolic AcidCell Line TumormedicineAnimalsHumansPhysical and Theoretical ChemistryParticle SizeOrganic ChemistryGlutathione0104 chemical scienceschemistryPVP; nanogels; e-beam; folate-targeting; doxorubicin; siRNA; GSH-responsive releasesiRNACancer cellNIH 3T3 CellsNanoparticlesSettore CHIM/07 - Fondamenti Chimici Delle TecnologieFolic Acid TransportersHeLa CellsMolecules
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Growth of Palladium Clusters on a Boron Nitride Nanotube Support

2015

We demonstrated that the migration process of a single palladium atom on the BNNT is not highly energy demanding and can be represented as a hopping mechanism between boron and nitrogen. A model was finally found for the interpretation of the growth energetics, showing that the process is generally favoured increasing the cluster size.

Palladium Boron Nitride Supported Catalyst DFT
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Determinants of elimination decisions in the activity scheduling process

2016

[EN] This paper presents an analysis on the determinants related to a particular rescheduling decision in the activity-travel scheduling process: elimination decisions, which consist in the non-execution of pre-planned activity-travel episodes. Data used come from an in-depth computer-assisted telephone interview (CATI) follow up survey carried out during the implementation of the first wave of an activity scheduling process panel survey. Open-ended answers related to the reasons associated to changes between pre-planned and executed agenda are studied. First, an interpretative qualitative method based on analytic induction (AI) is used to cope with the complex nature of the rescheduling de…

Panel surveyEngineeringOperations research0211 other engineering and technologiesScheduling (production processes)Transportation02 engineering and technologyINGENIERIA E INFRAESTRUCTURA DE LOS TRANSPORTESQualitative analysis0502 economics and businessActivity-based analysisFollow up survey050210 logistics & transportationbusiness.industryQualitative and quantitative study05 social sciencesActivity rescheduling decisions021107 urban & regional planningActivity schedulingQualitative analytic inductionEconometric modelTelephone interviewAnalytic inductionActivity scheduling processbusiness
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Changes in the Scheduling Process According to Observed Activity-travel Flexibility

2014

Abstract In this work we analyze the reasons for changing pre-planned activities and travels episodes considering the type of modification observed during the scheduling process. Specifically we selected a small sample from those pre-planned episodes that are no executed at all as a pilot study. The data analyzed was collected in the first wave of a weekly activity-travel panel survey carried out in Valencia (Spain) in 2010. Each survey wave consisted on a face-to-face interview to generate a pre-planned activity agenda for the following week, an activity-travel diary implemented on mobile phones to collect activities and travels as they are executed, and in-depth telephone interviews to in…

Panel surveyEngineeringbusiness.industryResource constraintsActivity Scheduling ProcessScheduling (production processes)Small sampleRescheduling analysisINGENIERIA E INFRAESTRUCTURA DE LOS TRANSPORTESQualitative analysisCategorizationGeneral Materials ScienceOperations managementQualitative AnalysisbusinessProcedia - Social and Behavioral Sciences
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Maternal and paternal feeding practices : links with young children’s eating behaviours and influencing factors : a systemic approach.

2021

Parents play a key role in the development of children’s eating preferences and behaviours. This doctoral project aimed to gain more insight into the feeding practices mothers and fathers use for pre-schoolers in France and Denmark. Four studies, combining quantitative and qualitative methods, were conducted to study the links between maternal and paternal feeding practices/styles and child eating behaviours, possible predictors of parental feeding and portioning practices, and gender differences in feeding practices and parental involvement in child feeding. Special attention was also paid to cultural influences and how changes in the context (due to the COVID-19 pandemic) can influence ea…

ParentsEnfants[SHS.PSY] Humanities and Social Sciences/PsychologyComportement alimentairePsychologiePratiques éducativesEating behaviour[SHS.PSY]Humanities and Social Sciences/PsychologyPsychologyChildrenFeeding practices
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Psychosocial factors related to the competitive anxiety of sports in training stages

2017

El objetivo de este trabajo es indagar la relación existente entre la ansiedad competitiva de futbolistas y tenistas en etapas de formación y la práctica de deporte por parte de los progenitores. Participaron en este estudio 246 niños deportistas de tenis y fútbol con una media de edad de 10,43 años (DT= 2,42), que han sido evaluados con un cuestionario de datos sociodemográficos y el cuestionario de Ansiedad Competitiva SAS-2 (Ramis, Torregrosa, Viladrich, & Cruz, 2010). Utilizando pruebas t de diferencias de medias independientes y pruebas no paramétricas, los resultados demuestran que los tenistas experimentan más ansiedad somática, mientras que los deportistas de menor edad presentan ma…

ParentsHealth (social science)05 social sciencesCompetitive anxietySports with/without cooperationPhysical Therapy Sports Therapy and RehabilitationIniciación deportiva050105 experimental psychology03 medical and health sciences0302 clinical medicinePadres y madresSport initiation0501 psychology and cognitive sciencesAnsiedad competitiva030217 neurology & neurosurgeryDeportes con/sin colaboración
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El transporte urbano colectivo en Valencia

1979

Parque de vehículosTráficoCongestión del tráficoUNESCO::HISTORIA::Historia por épocas::Historia antiguaTransporte urbanoTransporte colectivoDatos númericos:HISTORIA::Historia por épocas::Historia antigua [UNESCO]Accesibilidad
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